Age-related macular degeneration 8

Common Name(s)

Age-related macular degeneration 8

Age-related macular degeneration (ARMD) is a common complex disorder that affects the central region of the retina (macula) and is the leading cause of legal blindness in white Americans over age 65. Contributions of environmental factors and genetic susceptibility have been identified. The strongest nongenetic risk factor for ARMD is cigarette smoking. For a general phenotypic description and a discussion of genetic heterogeneity of ARMD, see {603075}.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Age-related macular degeneration 8" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Age-related macular degeneration 8" returned 2 free, full-text research articles on human participants. First 3 results:

Increase of 8-hydroxy-2'-deoxyguanosine in aqueous humor of patients with exudative age-related macular degeneration.
 

Author(s): Ling-Ing Lau, Catherine Jui-ling Liu, Yau-Huei Wei

Journal: Invest. Ophthalmol. Vis. Sci.. 2010 Nov;51(11):5486-90.

 

Oxidative stress has been implicated as a major contributor to age-related macular degeneration (AMD). 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is one of the most abundant oxidative products of DNA damage and represents a noninvasive and sensitive biomarker of oxidative stress. The authors ...

Last Updated: 28 Oct 2010

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A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
 

Author(s):

Journal: Arch. Ophthalmol.. 2001 Oct;119(10):1417-36.

 

Observational and experimental data suggest that antioxidant and/or zinc supplements may delay progression of age-related macular degeneration (AMD) and vision loss.

Last Updated: 11 Oct 2001

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Reviews from the PubMed Database

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The terms "Age-related macular degeneration 8" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular Age-related Macular Degeneration
 

Status: Recruiting

Condition Summary: Exudative Macular Degeneration; Retinal Hemorrhage

 

Last Updated: 24 Jun 2014

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