Adult hypophosphatasia

Common Name(s)

Adult hypophosphatasia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adult hypophosphatasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Adult hypophosphatasia" returned 5 free, full-text research articles on human participants. First 3 results:

"Atypical femoral fractures" during bisphosphonate exposure in adult hypophosphatasia.
 

Author(s): Roger A L Sutton, Steven Mumm, Stephen P Coburn, Karen L Ericson, Michael P Whyte

Journal: J. Bone Miner. Res.. 2012 May;27(5):987-94.

 

We report a 55-year-old woman who suffered atypical subtrochanteric femoral fractures (ASFFs) after 4 years of exposure to alendronate and then zolendronate given for "osteoporosis." Before alendronate treatment, she had low bone mineral density. After several months of therapy, metatarsal ...

Last Updated: 19 Apr 2012

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Intramedullary nailing for adult hypophosphatasia: a case report.
 

Author(s): H W Leung, C W Wong, W Y Shen

Journal: J Orthop Surg (Hong Kong). 2008 Dec;16(3):385-8.

 

Hypophosphatasia is a rare genetic metabolic disorder characterised by defective bone mineralisation secondary to serum and bone alkaline phosphatase deficiency. We report a 46-year-old woman who underwent multiple intramedullary nailings for fractures and deformities of 6 long bones over 13 years.

Last Updated: 7 Jan 2009

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Atypical femoral fractures, bisphosphonates, and adult hypophosphatasia.
 

Author(s): Michael P Whyte

Journal: J. Bone Miner. Res.. 2009 Jun;24(6):1132-4.

 

Lateral subtrochanteric femoral pseudofractures occurring in adults with osteomalacia from hypophosphatasia and X-linked hypophosphatemia support the hypothesis that atypical femoral fractures in osteoporosis treated with bisphosphonates also result from low bone turnover.

Last Updated: 25 May 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Adult hypophosphatasia" returned 1 free, full-text review articles on human participants. First 3 results:

Hypophosphatasia in an adult: a case report.
 

Author(s): M Nangaku, N Sato, K Sugano, F Takaku

Journal: Jpn. J. Med.. ;30(1):47-52.

 

In this rare case of adult hypophosphatasia, no radiological abnormalities of the skeletal system could be detected even by dual energy X-ray absorptiometry. Severe dental caries was the sole clinical manifestation, indicating this case as an "odontohypophosphatasia". The levels of ...

Last Updated: 11 Sep 1991

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Characterisation of Adult-Onset Hypophosphatasia
 

Status: Not yet recruiting

Condition Summary: Hypophosphatasia

 

Last Updated: 7 Jun 2016

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Last Updated: 8 Jun 2016

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Natural History Study of Patients With Hypophosphatasia (HPP)
 

Status: Recruiting

Condition Summary: Hypophosphatasia

 

Last Updated: 20 Jan 2016

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