Zygomycosis

Common Name(s)

Zygomycosis

Zygomycosis, also called mucormycosis, is a rare infection caused by a group of fungi called Mucoromycotina. These fungi are typically present in the soil and decaying organic matter such as leaves, compost piles, or rotten wood. Infection is more common among people who have weakened immune systems. People become infected by inhaling fungal spores, which can cause an infection to develop in the lungs, sinuses, eyes, and face. The fungus can also enter the skin through cuts, scrapes, or abrasions. Zygomycosis is not contagious and cannot be spread from person to person. Symptoms of Zygomycosis depend on where in the body the fungus is growing, but most commonly affects the sinuses or lungs. These symptoms can include fever, headache, and sinus pain. Lung infections from the fungus can cause fever and cough. When infected through the skin, symptoms can look like blisters or ulcers, and the infected tissue can turn black. Other symptoms include fever and tenderness, pain, heat, excessive redness, and swelling. If the infection is left untreated or not treated quickly, the fungus can spread to the rest of the body, and the infection is often fatal.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Zygomycosis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Zygomycosis" returned 80 free, full-text research articles on human participants. First 3 results:

Epidemiological aspects and clinical outcome of patients with Rhinocerebral zygomycosis: a survey in a referral hospital in Iran.
 

Author(s): Vida Bozorgi, Mahshid Talebitaher, Neda Shalbaf, Nima Radmanesh, Fatemeh Nasri, Mohammad Mostafa Ansari-Ramandi

Journal:

 

No comprehensive reports have been published on epidemiological status of Rhinocerebral zygomycosis infections and its outcome in our population, Hence, the current study came to address epidemiological characteristics as well as clinical outcome of patients with Rhinocerebral zygomycosis ...

Last Updated: 1 Nov 2016

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Severe invasive pulmonary zygomycosis by Rhizomucor pusillus and concomitant severe bacterial endocarditis in acute promyelocytic leukaemia.
 

Author(s): Roberta Rocconi, Sandra Mazzucato, Claudio Farina, Stefano Grandesso

Journal: Infez Med. 2015 Sep;23(3):265-9.

 

We describe a severe pulmonary invasive zygomycosis sustained by Rhizomucor pusillus and concomitant bacterial endocarditis in a woman diagnosed with acute promyelocytic leukaemia.

Last Updated: 24 Sep 2015

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Rhino facial zygomycosis: case report.
 

Author(s): Juliana Miguita e Souza, Antonio José Sproesser Junior, Alexandre Felippu Neto, Florencia Barbero Fuks, Carlos Augusto Cardim de Oliveira

Journal: Einstein (Sao Paulo). 2014 Sep;12(3):347-50.

 

Zygomycosis is an invasive disease that affects both immunocompetent and immunocompromised, depending on the type of strain. This disease diagnosis is clinical and histopathological, and its treatment is based on antifungal therapy and surgical cleaning. This paper reports a case ...

Last Updated: 9 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Zygomycosis" returned 31 free, full-text review articles on human participants. First 3 results:

Acute cutaneous zygomycosis of the scalp: A case report and literature review.
 

Author(s): Abdulrahman Alseady, Salim Baharoon

Journal: J Infect Public Health. ;8(4):377-81.

 

Cutaneous zygomycosis is the third most common form of zygomycosis. However, scalp involvement is rare for this disease. In this study, we present a case of acute zygomycosis in a diabetic patient who was effectively treated with local debridement, amphotericin B lipid complex and posaconazole.

Last Updated: 22 Jun 2015

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Rhinocerebral zygomycosis with pansinusitis in a 14-year-old girl with type 1 diabetes: a case report and review of the literature.
 

Author(s): Annalisa di Coste, Francesco Costantino, Luigi Tarani, Vincenzo Savastano, Claudio Di Biasi, Laura Schiavi, Ilaria Ernesti, Taulant Melengu, Marzia Duse

Journal:

 

Zygomycosis is a rare life-threatening fungal infection affecting mostly patients with predisposing conditions such as diabetes mellitus, immunodeficiency, haemochromatosis or major trauma.

Last Updated: 18 Dec 2013

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Zygomycosis in children: disseminated infection caused by Cunninghamella bertholletiae.
 

Author(s): M José González-Abad, Mercedes Alonso Sanz

Journal: Arch. Bronconeumol.. 2013 Jan;49(1):35.

 

Last Updated: 2 Jan 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Endoscopic Surgical Treatment of Rhino-Sinusal Mucormycosis
 

Status: Recruiting

Condition Summary: Rhinocerebral Mucormycosis

 

Last Updated: 12 Aug 2016

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Prospective Evaluation of a New Molecular Tool for Early Diagnosis of Mucormycosis
 

Status: Recruiting

Condition Summary: Mucormycosis

 

Last Updated: 22 Jul 2016

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