Zygomycosis

Common Name(s)

Zygomycosis

Zygomycosis, also called mucormycosis, is a rare infection caused by a group of fungi called Mucoromycotina. These fungi are typically present in the soil and decaying organic matter such as leaves, compost piles, or rotten wood. Infection is more common among people who have weakened immune systems. People become infected by inhaling fungal spores, which can cause an infection to develop in the lungs, sinuses, eyes, and face. The fungus can also enter the skin through cuts, scrapes, or abrasions. Zygomycosis is not contagious and cannot be spread from person to person. Symptoms of Zygomycosis depend on where in the body the fungus is growing, but most commonly affects the sinuses or lungs. These symptoms can include fever, headache, and sinus pain. Lung infections from the fungus can cause fever and cough. When infected through the skin, symptoms can look like blisters or ulcers, and the infected tissue can turn black. Other symptoms include fever and tenderness, pain, heat, excessive redness, and swelling. If the infection is left untreated or not treated quickly, the fungus can spread to the rest of the body, and the infection is often fatal.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Zygomycosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Zygomycosis" returned 106 free, full-text research articles on human participants. First 3 results:

Rhino facial zygomycosis: case report.
 

Author(s): Juliana Miguita e Souza, Antonio José Sproesser Junior, Alexandre Felippu Neto, Florencia Barbero Fuks, Carlos Augusto Cardim de Oliveira

Journal: Einstein (Sao Paulo). 2014 Sep;12(3):347-50.

 

Zygomycosis is an invasive disease that affects both immunocompetent and immunocompromised, depending on the type of strain. This disease diagnosis is clinical and histopathological, and its treatment is based on antifungal therapy and surgical cleaning. This paper reports a case ...

Last Updated: 9 Oct 2014

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Primary cutaneous zygomycosis secondary to minor trauma in an immunocompromised pediatric patient: a case report.
 

Author(s): Samantha Sirignano, Patrick Blake, Jake E Turrentine, Arturo R Dominguez

Journal:

 

Zygomycosis is an opportunistic infection generally found in immunocompromised individuals. Herein we present a pediatric patient with primary cutaneous mucormycosis that developed at a site of trauma. Diagnosis and treatment are discussed.

Last Updated: 20 Jun 2014

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Isolated renal zygomycosis in an immunocompetent patient.
 

Author(s): Ajay Kr Singh, Madhu Mati Goel, Chani Gupta, Suresh Kumar

Journal:

 

Zygomycosis is a rare opportunistic fungal infection in immunocompetent patients. Isolated renal involvement by zygomycosis is extremely rare and diagnosed mainly during postmortem study. We report a case of a 22-year-old man with right upper quadrant pain and fever. The CT of the ...

Last Updated: 6 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Zygomycosis" returned 35 free, full-text review articles on human participants. First 3 results:

Rhinocerebral zygomycosis with pansinusitis in a 14-year-old girl with type 1 diabetes: a case report and review of the literature.
 

Author(s): Annalisa di Coste, Francesco Costantino, Luigi Tarani, Vincenzo Savastano, Claudio Di Biasi, Laura Schiavi, Ilaria Ernesti, Taulant Melengu, Marzia Duse

Journal:

 

Zygomycosis is a rare life-threatening fungal infection affecting mostly patients with predisposing conditions such as diabetes mellitus, immunodeficiency, haemochromatosis or major trauma.

Last Updated: 18 Dec 2013

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Zygomycosis in children: disseminated infection caused by Cunninghamella bertholletiae.
 

Author(s): M José González-Abad, Mercedes Alonso Sanz

Journal: Arch. Bronconeumol.. 2013 Jan;49(1):35.

 

Last Updated: 2 Jan 2013

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Taxonomy of fungi causing mucormycosis and entomophthoramycosis (zygomycosis) and nomenclature of the disease: molecular mycologic perspectives.
 

Author(s): Kyung J Kwon-Chung

Journal: Clin. Infect. Dis.. 2012 Feb;54 Suppl 1():S8-S15.

 

Molecular phylogenetic analysis confirmed the phylum Zygomycota to be polyphyletic, and the taxa conventionally classified in Zygomycota are now distributed among the new phylum Glomeromycota and 4 subphyla incertae sedis (uncertain placement). Because the nomenclature of the disease ...

Last Updated: 16 Jan 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Endoscopic Surgical Treatment of Rhino-Sinusal Mucormycosis
 

Status: Recruiting

Condition Summary: Rhinocerebral Mucormycosis

 

Last Updated: 12 Aug 2016

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Prospective Evaluation of a New Molecular Tool for Early Diagnosis of Mucormycosis
 

Status: Recruiting

Condition Summary: Mucormycosis

 

Last Updated: 22 Jul 2016

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