ZAP-70 deficiency

Common Name(s)

ZAP-70 deficiency

ZAP-70 deficiency is an acronym for Zeta-Associated Protein 70 Deficiency. Individuals who have ZAP-70 deficiency present during infancy or early childhood with recurrent infections similar to those in severe combined immunodeficiency (SCID); however, they live longer, and the deficiency may not be diagnosed until they are several years old. The disorder is fatal unless treated by bone marrow transplantation.

Diagnosis is similar to that for severe combined immunodeficiency.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "ZAP-70 deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "ZAP-70 deficiency" returned 1 free, full-text research articles on human participants. First 3 results:

[Primary immunodeficiency secondary to ZAP-70 deficiency].
 

Author(s): L T Barata, R Henriques, C Hivroz, E Jouanguy, A Paiva, A M Freitas, H B Coimbra, A Fischer, H C da Mota

Journal: Acta Med Port. ;14(4):413-7.

 

The authors present the case of a child with recurrent infections since the age of 4 months, including bilateral pneumonia by Pneumocystis carinii and protracted varicella. Serum immunoglobulin values (when 10 months old), and B cell values were normal. There was persistent lymphocytic ...

Last Updated: 12 Dec 2001

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "ZAP-70 deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.