Yaws

Common Name(s)

Yaws

Yaws is a tropical disease caused by a form of bacteria known as treponemes that affects the skin, bone, and cartilage. This disease mainly affects children under the age of 15, and is found primarily in poor communities in warm, humid, and tropical forest areas of Africa, Asia, Latin America, and the Pacific. Yaws is transmitted from person to person through direct non-sexual contact with the fluids from the lesion of an infected person. Signs and symptoms include an early infectious stage and a late non-infectious stage. During the early infectious stage, an initial clear, circular swelling of the skin will develop at the site of entry. Other signs in the early stage are thinkening and darkening of the palms of the hands and soles of the feet. Bone pain and bone lesions may also appear in the early stage. Late Yaws symptoms appear five years after the initial infection and include disfigurement of the nose and bones and thickening of the palms of the hand and the soles of the feet. Humans are the only reservoir of Yaws.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Yaws" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Yaws" returned 57 free, full-text research articles on human participants. First 3 results:

Eradication of yaws in India.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Apr;90(15):161-8.

 

Last Updated: 22 Apr 2015

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Mass treatment with single-dose azithromycin for yaws.
 

Author(s): Oriol Mitjà, Wendy Houinei, Penias Moses, August Kapa, Raymond Paru, Russell Hays, Sheila Lukehart, Charmie Godornes, Sibauk Vivaldo Bieb, Tim Grice, Peter Siba, David Mabey, Sergi Sanz, Pedro L Alonso, Kingsley Asiedu, Quique Bassat

Journal: N. Engl. J. Med.. 2015 Feb;372(8):703-10.

 

Mass treatment with azithromycin is a central component of the new World Health Organization (WHO) strategy to eradicate yaws. Empirical data on the effectiveness of the strategy are required as a prerequisite for worldwide implementation of the plan.

Last Updated: 19 Feb 2015

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Yaws eradication--a goal finally within reach.
 

Author(s): James W Kazura

Journal: N. Engl. J. Med.. 2015 Feb;372(8):693-5.

 

Last Updated: 19 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Yaws" returned 4 free, full-text review articles on human participants. First 3 results:

Advances in the diagnosis of endemic treponematoses: yaws, bejel, and pinta.
 

Author(s): Oriol Mitjà, David Šmajs, Quique Bassat

Journal:

 

Improved understanding of the differential diagnosis of endemic treponematoses is needed to inform clinical practice and to ensure the best outcome for a new global initiative for the eradication of yaws, bejel, and pinta. Traditionally, the human treponematoses have been differentiated ...

Last Updated: 8 Nov 2013

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Yaws eradication: facing old problems, raising new hopes.
 

Author(s): Andrea Rinaldi

Journal: PLoS Negl Trop Dis. 2012 ;6(11):e1837.

 

Last Updated: 4 Dec 2012

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New treatment schemes for yaws: the path toward eradication.
 

Author(s): Oriol Mitjà, Russell Hays, Andrea C Rinaldi, Robyn McDermott, Robyn McDermot, Quique Bassat

Journal: Clin. Infect. Dis.. 2012 Aug;55(3):406-12.

 

Last Updated: 12 Jul 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of Two Different Doses of Azithromycin for Treatment of Yaws
 

Status: Recruiting

Condition Summary: Yaws

 

Last Updated: 16 Aug 2015

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Functioning Disturbance in Chronic Back Pain: Altered Muscle Metabolism
 

Status: Recruiting

Condition Summary: Chronic Non-specific Low Back Pian

 

Last Updated: 7 May 2012

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