Yaws

Common Name(s)

Yaws

Yaws is a tropical disease caused by a form of bacteria known as treponemes that affects the skin, bone, and cartilage. This disease mainly affects children under the age of 15, and is found primarily in poor communities in warm, humid, and tropical forest areas of Africa, Asia, Latin America, and the Pacific. Yaws is transmitted from person to person through direct non-sexual contact with the fluids from the lesion of an infected person. Signs and symptoms include an early infectious stage and a late non-infectious stage. During the early infectious stage, an initial clear, circular swelling of the skin will develop at the site of entry. Other signs in the early stage are thinkening and darkening of the palms of the hands and soles of the feet. Bone pain and bone lesions may also appear in the early stage. Late Yaws symptoms appear five years after the initial infection and include disfigurement of the nose and bones and thickening of the palms of the hand and the soles of the feet. Humans are the only reservoir of Yaws.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Yaws" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Yaws" returned 95 free, full-text research articles on human participants. First 3 results:

Eradication of yaws in India.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Apr;90(15):161-8.

 

Last Updated: 22 Apr 2015

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Mass treatment with single-dose azithromycin for yaws.
 

Author(s): Oriol Mitjà, Wendy Houinei, Penias Moses, August Kapa, Raymond Paru, Russell Hays, Sheila Lukehart, Charmie Godornes, Sibauk Vivaldo Bieb, Tim Grice, Peter Siba, David Mabey, Sergi Sanz, Pedro L Alonso, Kingsley Asiedu, Quique Bassat

Journal: N. Engl. J. Med.. 2015 Feb;372(8):703-10.

 

Mass treatment with azithromycin is a central component of the new World Health Organization (WHO) strategy to eradicate yaws. Empirical data on the effectiveness of the strategy are required as a prerequisite for worldwide implementation of the plan.

Last Updated: 19 Feb 2015

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Yaws eradication--a goal finally within reach.
 

Author(s): James W Kazura

Journal: N. Engl. J. Med.. 2015 Feb;372(8):693-5.

 

Last Updated: 19 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Yaws" returned 7 free, full-text review articles on human participants. First 3 results:

Challenges and key research questions for yaws eradication.
 

Author(s): Michael Marks, Oriol Mitjà, Lasse S Vestergaard, Allan Pillay, Sascha Knauf, Cheng-Yen Chen, Quique Bassat, Diana L Martin, David Fegan, Fasihah Taleo, Jacob Kool, Sheila Lukehart, Paul M Emerson, Anthony W Solomon, Tun Ye, Ronald C Ballard, David C W Mabey, Kingsley B Asiedu

Journal: Lancet Infect Dis. 2015 Oct;15(10):1220-5.

 

Yaws is endemic in west Africa, southeast Asia, and the Pacific region. To eradicate yaws by 2020, WHO has launched a campaign of mass treatment with azithromycin. Progress has been made towards achievement of this ambitious goal, including the validation of point-of-care and molecular ...

Last Updated: 14 Oct 2015

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Eradication of yaws: historical efforts and achieving WHO's 2020 target.
 

Author(s): Kingsley Asiedu, Christopher Fitzpatrick, Jean Jannin

Journal:

 

Yaws, one of the 17 neglected tropical diseases (NTDs), is targeted for eradication by 2020 in resolution WHA66.12 of the World Health Assembly (2013) and the WHO roadmap on NTDs (2012). The disease frequently affects children who live in poor socioeconomic conditions. Between 1952 ...

Last Updated: 26 Sep 2014

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Yaws.
 

Author(s): Michael Marks, Dornubari Lebari, Anthony W Solomon, Stephen P Higgins

Journal: Int J STD AIDS. 2015 Sep;26(10):696-703.

 

Yaws is a non-venereal endemic treponemal infection caused by Treponema pallidum sub-species pertenue, a spirochaete bacterium closely related to Treponema pallidum ssp. pallidum, the agent of venereal syphilis. Yaws is a chronic, relapsing disease predominantly affecting children ...

Last Updated: 3 Aug 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of Two Different Doses of Azithromycin for Treatment of Yaws
 

Status: Recruiting

Condition Summary: Yaws

 

Last Updated: 16 Aug 2015

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Functioning Disturbance in Chronic Back Pain: Altered Muscle Metabolism
 

Status: Recruiting

Condition Summary: Chronic Non-specific Low Back Pian

 

Last Updated: 7 May 2012

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Transcutaneous Electrical Acupoint Stimulation for Non-small Cell Lung Cancer Patients
 

Status: Recruiting

Condition Summary: Non-Small Cell Lung Cancer; Lung Cancer

 

Last Updated: 21 Jan 2016

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