Wolff Parkinson White syndrome

Common Name(s)

Wolff Parkinson White syndrome, Wolff-Parkinson-White pattern, Wolff-Parkinson-White Syndrome, Ventricular familial preexcitation syndrome

Wolff-Parkinson-White syndrome is a condition characterized by a disruption of the heart's normal rhythm (arrhythmia). People with this condition are born with a heart abnormality that can disrupt the coordinated movement of electrical signals through the heart.  This abnormaility leads to an abnormally fast heartbeat (tachycardia) and other arrhythmias. In most cases, the cause of Wolff-Parkinson-White syndrome is unknown. A small percentage of cases are caused by mutations in the PRKAG2 gene. These cases appear to be inherited in an autosomal dominant manner.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wolff Parkinson White syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 30 Oct 2012

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SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wolff Parkinson White syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 29 Apr 2014

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General Support Organizations

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General Resources

SADS Foundation Website

Information on living with SADS, diagnosis, treatment, prevention, and advocacy/education.

Updated 29 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wolff Parkinson White syndrome" returned 195 free, full-text research articles on human participants. First 3 results:

LEOPARD syndrome with Wolff-Parkinson-White syndrome on electrocardiography.
 

Author(s): Sangita Ghosh, Soumik Chaudhuri, Vijay Kumar Jain

Journal: Indian J Dermatol Venereol Leprol. ;79(6):821-4.

 

Last Updated: 1 Nov 2013

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Wolff-Parkinson-White syndrome "cured" by myocardial infarction?
 

Author(s): Renguang Liu, Qinghua Chang

Journal: CMAJ. 2014 May;186(8):E297.

 

Last Updated: 13 May 2014

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Mitral valve injury after radiofrequency ablation for Wolff-Parkinson-White syndrome.
 

Author(s): Juan G Penaranda Canal, Maurice Enriquez-Sarano, Samuel J Asirvatham, Thomas M Munger, Paul A Friedman, Rakesh M Suri

Journal: Circulation. 2013 Jun;127(25):2551-2.

 

Last Updated: 26 Jun 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wolff Parkinson White syndrome" returned 9 free, full-text review articles on human participants. First 3 results:

Asymptomatic Wolff-Parkinson-White syndrome: incidental ECG diagnosis and a review of literature regarding current treatment.
 

Author(s): Alexander Liu, Pawan Pusalkar

Journal:

 

A 19-year-old male presented with periorbital cellulitis responsive to intravenous antibiotics. A routine ECG on admission showed slurred upstroke of the QRS complexes consistent with Wolff-Parkinson-White syndrome (WPW). He has never experienced any cardiac-related symptoms. Once ...

Last Updated: 13 Jun 2012

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Mechanisms for the genesis of paroxysmal atrial fibrillation in the Wolff Parkinson-White syndrome: intrinsic atrial muscle vulnerability vs. electrophysiological properties of the accessory pathway.
 

Author(s): Osmar Antonio CenturiĆ³n, Akihiko Shimizu, Shojiro Isomoto, Atsushi Konoe

Journal: Europace. 2008 Mar;10(3):294-302.

 

Paroxysmal atrial fibrillation (PAF) develops in up to one-third of patients with the Wolff Parkinson-White syndrome (WPW). The reason for this high incidence of PAF in the WPW syndrome is not yet clearly understood. When PAF appears in patients with WPW syndrome who have anterograde ...

Last Updated: 29 Feb 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.