Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1468 free, full-text research articles on human participants. First 3 results:

Persistence of T-cell immune response induced by two acellular pertussis vaccines in children five years after primary vaccination.
 

Author(s): Raffaella Palazzo, Maria Carollo, Manuela Bianco, Giorgio Fedele, Ilaria Schiavoni, Elisabetta Pandolfi, Alberto Villani, Alberto E Tozzi, Françoise Mascart, Clara M Ausiello

Journal: New Microbiol.. 2016 Jan;39(1):35-47.

 

The resurgence of pertussis suggests the need for greater efforts to understand the long-lasting protective responses induced by vaccination. In this paper we dissect the persistence of T memory responses induced by primary vaccination with two different acellular pertussis (aP) vaccines, ...

Last Updated: 29 Feb 2016

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Increasing incidence of pertussis in Brazil: a retrospective study using surveillance data.
 

Author(s): Lucas Melo Guimarães, Eduilson Lívio Neves da Costa Carneiro, Filipe Anibal Carvalho-Costa

Journal:

 

Many countries have reported an increase in the incidence of pertussis, which has become a global public health concern.

Last Updated: 27 Oct 2015

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Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014).
 

Author(s): Ying Yang, Kaihu Yao, Xiang Ma, Wei Shi, Lin Yuan, Yonghong Yang

Journal:

 

To investigate changes in virulence-related genotypes and in the antimicrobial susceptibility of Bordetella pertussis isolates collected from the 1970s to 2014 in the northern part of China.

Last Updated: 26 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 82 free, full-text review articles on human participants. First 3 results:

Roads to the development of improved pertussis vaccines paved by immunology.
 

Author(s): Jolanda Brummelman, Mieszko M Wilk, Wanda G H Han, Cécile A C M van Els, Kingston H G Mills

Journal: Pathog Dis. 2015 Nov;73(8):ftv067.

 

Current acellular pertussis vaccines have various shortcomings, which may contribute to their suboptimal efficacy and waning immunity in vaccinated populations. This calls for the development of new pertussis vaccines capable of inducing long-lived protective immunity. Immunization ...

Last Updated: 19 Sep 2015

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The burden of pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunization (EPI) in 1974: a systematic review protocol.
 

Author(s): Rudzani Muloiwa, Benjamin M Kagina, Mark E Engel, Gregory D Hussey

Journal:

 

Vaccine against pertussis has been in use for several decades. Despite the widespread use of pertussis vaccine, evidence shows resurgence of pertussis in high-income countries. Pertussis surveillance data is largely missing from low- and middle-income countries (LMICs). Without data ...

Last Updated: 6 May 2015

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Prevention of pertussis through adult vaccination.
 

Author(s): Manika Suryadevara, Joseph B Domachowske

Journal: Hum Vaccin Immunother. 2015 ;11(7):1744-7.

 

Pertussis is a vaccine preventable respiratory infection. Young infants are at high risk of developing severe complications from infection. Despite high rates of pediatric vaccine uptake, there continues to be increases in pertussis cases, likely due to waning immunity from childhood ...

Last Updated: 7 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine
 

Status: Recruiting

Condition Summary: Pertussis; Whooping Cough

 

Last Updated: 5 Oct 2015

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Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects
 

Status: Recruiting

Condition Summary: Tetanus; Diphtheria; Pertussis; Whooping Cough

 

Last Updated: 22 Apr 2016

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Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 29 Jul 2015

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