Whooping cough

Common Name(s)

Whooping cough, Pertussis

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Whooping cough" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Whooping cough" returned 177 free, full-text research articles on human participants. First 3 results:

Whooping cough in school age children presenting with persistent cough in UK primary care after introduction of the preschool pertussis booster vaccination: prospective cohort study.
 

Author(s): Kay Wang, Norman K Fry, Helen Campbell, Gayatri Amirthalingam, Timothy G Harrison, David Mant, Anthony Harnden

Journal:

 

To estimate the prevalence and clinical severity of whooping cough (pertussis) in school age children presenting with persistent cough in primary care since the introduction and implementation of the preschool pertussis booster vaccination.

Last Updated: 25 Jun 2014

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Prevalence and genotype distribution of Pneumocystis jirovecii in Cuban infants and toddlers with whooping cough.
 

Author(s): Ernesto X Monroy-Vaca, Yaxsier de Armas, María T Illnait-Zaragozí, Gilda Toraño, Raúl Diaz, Dania Vega, Ileana Alvarez-Lam, Enrique J Calderón, Christen R Stensvold

Journal: J. Clin. Microbiol.. 2014 Jan;52(1):45-51.

 

This study describes the prevalence and genotype distribution of Pneumocystis jirovecii obtained from nasopharyngeal (NP) swabs from immunocompetent Cuban infants and toddlers with whooping cough (WC). A total of 163 NP swabs from 163 young Cuban children with WC who were admitted ...

Last Updated: 23 Dec 2013

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Persistence in epidemic metapopulations: quantifying the rescue effects for measles, mumps, rubella and whooping cough.
 

Author(s): C Jessica E Metcalf, Katie Hampson, Andrew J Tatem, Bryan T Grenfell, Ottar N Bjørnstad

Journal:

 

Metapopulation rescue effects are thought to be key to the persistence of many acute immunizing infections. Yet the enhancement of persistence through spatial coupling has not been previously quantified. Here we estimate the metapopulation rescue effects for four childhood infections ...

Last Updated: 16 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Whooping cough" returned 3 free, full-text review articles on human participants. First 3 results:

Development of improved vaccines against whooping cough: current status.
 

Author(s): Ibrahim Marzouqi, Peter Richmond, Scott Fry, John Wetherall, Trilochan Mukkur

Journal: Hum Vaccin. 2010 Jul;6(7):543-53.

 

Prior to the introduction of killed whole cell pertussis vaccine [wP] in the 1940s, whooping cough was a major cause of infant death worldwide. Widespread vaccination of children with this vaccine caused a significant reduction in mortality. However in the 1990s and now more recently, ...

Last Updated: 13 Jan 2011

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[Whooping cough--an increasing problem in Norway].
 

Author(s): Susanne Gjeruldsen Dudman, Marius Trøseid, Tom Øystein Jonassen, Martin Steinbakk

Journal: Tidsskr. Nor. Laegeforen.. 2006 Jan;126(3):305-8.

 

The incidence of whooping cough has increased in recent years in Norway, especially amongst older children and adults; in 2004 it was 168/100,000.

Last Updated: 27 Jan 2006

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Progress with a recombinant whooping cough vaccine: a review.
 

Author(s): W N Burnette, V L Mar, D W Whiteley, T D Bartley

Journal: J R Soc Med. 1992 May;85(5):285-7.

 

Last Updated: 3 Dec 1992

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 May 2014

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A Study to Determine the Seroprevalence of Bordetella Pertussis in Adults in Hungary
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 24 Jul 2014

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Pertussis (Tdap) Vaccination in Pregnancy
 

Status: Recruiting

Condition Summary: Pertussis; Pregnancy

 

Last Updated: 28 Sep 2012

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