Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1291 free, full-text research articles on human participants. First 3 results:

Tetanus, diphtheria, pertussis vaccination coverage before, during, and after pregnancy - 16 States and New York City, 2011.
 

Author(s): Indu B Ahluwalia, Helen Ding, Denise D'Angelo, Kristen H Shealy, James A Singleton, Jennifer Liang, Kenneth D Rosenberg,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 May;64(19):522-6.

 

In June 2011, the Advisory Committee on Immunizations Practices (ACIP) recommended 1 dose of a tetanus, diphtheria, and acellular pertussis (Tdap) vaccine during pregnancy for women who had not received Tdap previously. Before 2011, Tdap was recommended for unvaccinated women either ...

Last Updated: 22 May 2015

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Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals.
 

Author(s): Carolyn M Nielsen, Matthew J White, Christian Bottomley, Chiara Lusa, Ana Rodríguez-Galán, Scarlett E G Turner, Martin R Goodier, Eleanor M Riley

Journal: J. Immunol.. 2015 May;194(10):4657-67.

 

NK cells contribute to postvaccination immune responses after activation by IL-2 from Ag-specific memory T cells or by cross-linking of the low-affinity IgG receptor, CD16, by Ag-Ab immune complexes. Sensitivity of NK cells to these signals from the adaptive immune system is heterogeneous ...

Last Updated: 2 May 2015

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Testing implications of varying targets for Bordetella pertussis: comparison of the FilmArray Respiratory Panel and the Focus B. pertussis PCR assay.
 

Author(s): Robert C Jerris, Sally R Williams, Heather J MacDonald, Danielle R Ingebrigtsen, Lars F Westblade, Beverly B Rogers

Journal: J. Clin. Pathol.. 2015 May;68(5):394-6.

 

The FilmArray Respiratory Panel (RP) detects multiple pathogens, including Bordetella pertussis. The multiplex PCR system is appropriate for a core laboratory or point of care due to ease of use. The purpose of this study is to compare the analytical sensitivity of the FilmArray RP, ...

Last Updated: 17 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 72 free, full-text review articles on human participants. First 3 results:

Epidemiology of pertussis in Italy: disease trends over the last century.
 

Author(s): M V Gonfiantini, E Carloni, F Gesualdo, E Pandolfi, E Agricola, E Rizzuto, S Iannazzo, M L Ciofi Degli Atti, A Villani, A E Tozzi

Journal:

 

We reviewed the epidemiology of pertussis in Italy over the last 125 years to identify disease trends and factors that could have influenced these trends. We described mortality rates (1888-2012), case fatality rates (1925-2012), cumulative incidence rates (1925-2013) and age-specific ...

Last Updated: 17 Oct 2014

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Revised guidance on the choice of pertussis vaccines: July 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 Jul;89(30):337-40.

 

Last Updated: 28 Jul 2014

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Pertussis vaccine trials in the 1990s.
 

Author(s): Linda C Lambert

Journal: J. Infect. Dis.. 2014 Apr;209 Suppl 1():S4-9.

 

The significant burden of disease due to pertussis, which predominantly affects newborns during their first few months of life, was substantially decreased following the introduction of inactivated whole-bacterial-cell vaccines in the middle of the 20th century. Although these vaccines ...

Last Updated: 14 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine
 

Status: Not yet recruiting

Condition Summary: Pertussis; Whooping Cough

 

Last Updated: 20 May 2015

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Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 29 Jul 2015

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Last Updated: 26 May 2015

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