Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1513 free, full-text research articles on human participants. First 3 results:

Persistence of T-cell immune response induced by two acellular pertussis vaccines in children five years after primary vaccination.
 

Author(s): Raffaella Palazzo, Maria Carollo, Manuela Bianco, Giorgio Fedele, Ilaria Schiavoni, Elisabetta Pandolfi, Alberto Villani, Alberto E Tozzi, Françoise Mascart, Clara M Ausiello

Journal: New Microbiol.. 2016 Jan;39(1):35-47.

 

The resurgence of pertussis suggests the need for greater efforts to understand the long-lasting protective responses induced by vaccination. In this paper we dissect the persistence of T memory responses induced by primary vaccination with two different acellular pertussis (aP) vaccines, ...

Last Updated: 29 Feb 2016

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Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis.
 

Author(s): Wanda G H Han, Hennie M Hodemaekers, Bhawani Nagarajah, Martien M C Poelen, Kina Helm, Riny Janssen, Cécile A C M van Els

Journal:

 

Pertussis, caused by infection with the gram negative B. pertussis bacterium, is a serious respiratory illness that can last for months. While B. pertussis infection rates are estimated between 1-10% in the general population, notifications of symptomatic pertussis only comprise 0.01-0.1% ...

Last Updated: 20 Feb 2016

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The Use of Innovative Two-Component Cluster Analysis and Serodiagnostic Cut-Off Methods to Estimate Prevalence of Pertussis Reinfections.
 

Author(s): Inonge van Twillert, Axel A Bonačić Marinović, Jacqueline A M van Gaans-van den Brink, Betsy Kuipers, Guy A M Berbers, Nicoline A T van der Maas, Theo J M Verheij, Florens G A Versteegh, Peter F M Teunis, Cécile A C M van Els

Journal:

 

Bordetella pertussis circulates even in highly vaccinated countries affecting all age groups. Insight into the scale of concealed reinfections is important as they may contribute to transmission. We therefore investigated whether current single-point serodiagnostic methods are suitable ...

Last Updated: 6 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 87 free, full-text review articles on human participants. First 3 results:

[Is it time to vaccine pregnant woman against pertussis?].
 

Author(s): José Cofré

Journal: Rev Chilena Infectol. 2016 Feb;33(1):55-8.

 

Pertussis may cause death in neonates and very young infants. In these ages pertussis vaccine has not been administered yet or infants haven't received enough doses of vaccine to protect them. Cocoon strategy have been implemented in several countries and has limited efficacy because ...

Last Updated: 11 Mar 2016

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Pertussis immunisation in pregnancy: a summary of funded Australian state and territory programs.
 

Author(s): Frank H Beard

Journal:

 

The Australian Immunisation Handbook, 10th edition now recommends pertussis vaccination during pregnancy as the preferred option for protecting vulnerable young infants. Jurisdictionally funded pertussis immunisation programs for pregnant women have been progressively introduced in ...

Last Updated: 1 Dec 2015

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Roads to the development of improved pertussis vaccines paved by immunology.
 

Author(s): Jolanda Brummelman, Mieszko M Wilk, Wanda G H Han, Cécile A C M van Els, Kingston H G Mills

Journal: Pathog Dis. 2015 Nov;73(8):ftv067.

 

Current acellular pertussis vaccines have various shortcomings, which may contribute to their suboptimal efficacy and waning immunity in vaccinated populations. This calls for the development of new pertussis vaccines capable of inducing long-lived protective immunity. Immunization ...

Last Updated: 19 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine
 

Status: Recruiting

Condition Summary: Pertussis; Whooping Cough

 

Last Updated: 5 Oct 2015

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Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 29 Jul 2015

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Last Updated: 26 May 2015

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