Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1347 free, full-text research articles on human participants. First 3 results:

Surveillance of infant pertussis in Sweden 1998-2012; severity of disease in relation to the national vaccination programme.
 

Author(s): R M Carlsson, K von Segebaden, J Bergstrom, A M Kling, L Nilsson

Journal:

 

In Sweden, pertussis was excluded from the national vaccination programme in 1979 until acellular vaccination was introduced in a highly endemic setting in 1996. The general incidence dropped 10-fold within a decade, less in infants. Infant pertussis reached 40-45 cases per 100,000 ...

Last Updated: 20 Feb 2015

Go To URL
Notes from the field: investigation of contacts of a health care worker who worked while ill with pertussis--Maryland, August-September 2014.
 

Author(s): Kasi M Chu, Lucas A Johnson,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Jan;64(2):45.

 

On September 5, 2014, the public health department of a Maryland hospital was notified of a case of Bordetella pertussis infection confirmed by polymerase chain reaction (PCR) in a staff health care worker (HCW). The HCW experienced onset of diarrhea and malaise (nonrespiratory symptoms ...

Last Updated: 23 Jan 2015

Go To URL
Pertussis epidemic--California, 2014.
 

Author(s): Kathleen Winter, Carol Glaser, James Watt, Kathleen Harriman,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Dec;63(48):1129-32.

 

On June 13, 2014, the California Department of Public Health (CDPH) declared that a pertussis epidemic was occurring in the state when reported incidence was more than five times greater than baseline levels. The incidence of pertussis in the United States is cyclical, with peaks ...

Last Updated: 5 Dec 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 76 free, full-text review articles on human participants. First 3 results:

Epidemiology of pertussis in Italy: disease trends over the last century.
 

Author(s): M V Gonfiantini, E Carloni, F Gesualdo, E Pandolfi, E Agricola, E Rizzuto, S Iannazzo, M L Ciofi Degli Atti, A Villani, A E Tozzi

Journal:

 

We reviewed the epidemiology of pertussis in Italy over the last 125 years to identify disease trends and factors that could have influenced these trends. We described mortality rates (1888-2012), case fatality rates (1925-2012), cumulative incidence rates (1925-2013) and age-specific ...

Last Updated: 17 Oct 2014

Go To URL
Revised guidance on the choice of pertussis vaccines: July 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 Jul;89(30):337-40.

 

Last Updated: 28 Jul 2014

Go To URL
Pertussis vaccine trials in the 1990s.
 

Author(s): Linda C Lambert

Journal: J. Infect. Dis.. 2014 Apr;209 Suppl 1():S4-9.

 

The significant burden of disease due to pertussis, which predominantly affects newborns during their first few months of life, was substantially decreased following the introduction of inactivated whole-bacterial-cell vaccines in the middle of the 20th century. Although these vaccines ...

Last Updated: 14 Mar 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine
 

Status: Not yet recruiting

Condition Summary: Pertussis; Whooping Cough

 

Last Updated: 20 May 2015

Go to URL

Last Updated: 26 May 2015

Go to URL
Seroepidemiological Study of Pertussis and Other Infectious Diseases
 

Status: Recruiting

Condition Summary: Pertussis Infection

 

Last Updated: 30 Sep 2013

Go to URL