Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1490 free, full-text research articles on human participants. First 3 results:

Persistence of T-cell immune response induced by two acellular pertussis vaccines in children five years after primary vaccination.
 

Author(s): Raffaella Palazzo, Maria Carollo, Manuela Bianco, Giorgio Fedele, Ilaria Schiavoni, Elisabetta Pandolfi, Alberto Villani, Alberto E Tozzi, Françoise Mascart, Clara M Ausiello

Journal: New Microbiol.. 2016 Jan;39(1):35-47.

 

The resurgence of pertussis suggests the need for greater efforts to understand the long-lasting protective responses induced by vaccination. In this paper we dissect the persistence of T memory responses induced by primary vaccination with two different acellular pertussis (aP) vaccines, ...

Last Updated: 29 Feb 2016

Go To URL
Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis.
 

Author(s): Wanda G H Han, Hennie M Hodemaekers, Bhawani Nagarajah, Martien M C Poelen, Kina Helm, Riny Janssen, Cécile A C M van Els

Journal:

 

Pertussis, caused by infection with the gram negative B. pertussis bacterium, is a serious respiratory illness that can last for months. While B. pertussis infection rates are estimated between 1-10% in the general population, notifications of symptomatic pertussis only comprise 0.01-0.1% ...

Last Updated: 20 Feb 2016

Go To URL
The Use of Innovative Two-Component Cluster Analysis and Serodiagnostic Cut-Off Methods to Estimate Prevalence of Pertussis Reinfections.
 

Author(s): Inonge van Twillert, Axel A Bonačić Marinović, Jacqueline A M van Gaans-van den Brink, Betsy Kuipers, Guy A M Berbers, Nicoline A T van der Maas, Theo J M Verheij, Florens G A Versteegh, Peter F M Teunis, Cécile A C M van Els

Journal:

 

Bordetella pertussis circulates even in highly vaccinated countries affecting all age groups. Insight into the scale of concealed reinfections is important as they may contribute to transmission. We therefore investigated whether current single-point serodiagnostic methods are suitable ...

Last Updated: 6 Feb 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 85 free, full-text review articles on human participants. First 3 results:

Roads to the development of improved pertussis vaccines paved by immunology.
 

Author(s): Jolanda Brummelman, Mieszko M Wilk, Wanda G H Han, Cécile A C M van Els, Kingston H G Mills

Journal: Pathog Dis. 2015 Nov;73(8):ftv067.

 

Current acellular pertussis vaccines have various shortcomings, which may contribute to their suboptimal efficacy and waning immunity in vaccinated populations. This calls for the development of new pertussis vaccines capable of inducing long-lived protective immunity. Immunization ...

Last Updated: 19 Sep 2015

Go To URL
Strategies to decrease pertussis transmission to infants.
 

Author(s): Kevin Forsyth, Stanley Plotkin, Tina Tan, Carl Heinz Wirsing von König

Journal: Pediatrics. 2015 Jun;135(6):e1475-82.

 

The Global Pertussis Initiative (GPI) is an expert scientific forum addressing the worldwide burden of pertussis, which remains a serious health issue, especially in infants. This age cohort is at risk for developing pertussis by transmission from those in close proximity. Risk is ...

Last Updated: 2 Jun 2015

Go To URL
The burden of pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunization (EPI) in 1974: a systematic review protocol.
 

Author(s): Rudzani Muloiwa, Benjamin M Kagina, Mark E Engel, Gregory D Hussey

Journal:

 

Vaccine against pertussis has been in use for several decades. Despite the widespread use of pertussis vaccine, evidence shows resurgence of pertussis in high-income countries. Pertussis surveillance data is largely missing from low- and middle-income countries (LMICs). Without data ...

Last Updated: 6 May 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine
 

Status: Recruiting

Condition Summary: Pertussis; Whooping Cough

 

Last Updated: 5 Oct 2015

Go to URL
Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects
 

Status: Recruiting

Condition Summary: Tetanus; Diphtheria; Pertussis; Whooping Cough

 

Last Updated: 6 Jun 2016

Go to URL
Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 29 Jul 2015

Go to URL