Pertussis

Common Name(s)

Pertussis, Whooping cough

Whooping cough, also called pertussis, is a highly contagious respiratory tract infection. Whooping cough primarily affects young children who have not completed the full course of vaccinations. Symptoms appear mild at first including runny nose, sneezing, mild fever, and dry cough. After one to two weeks, the symptoms worsen. More severe symptoms include prolonged coughing attacks that provoke vomitting, result in red or blue face, and cause extreme fatigue. During coughing attacks the coughs may end with a high-pitched "whoop" sound during an inhale.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pertussis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pertussis" returned 1461 free, full-text research articles on human participants. First 3 results:

Severe pertussis infection: A clinicopathological study.
 

Author(s): Fernando Palvo, Alexandre Todorovic Fabro, Maria Célia Cervi, Davi Casale Aragon, Fernando Silva Ramalho, Ana Paula de Carvalho Panzeri Carlotti

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8823.

 

We aimed to investigate the clinicopathological features of pertussis in children admitted to a tertiary-care university hospital in Brazil.This was a retrospective cohort study of all pediatric hospital admissions with pertussis from January 1, 2008 to December 31, 2014. We also ...

Last Updated: 31 Dec 1969

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When Escherichia coli doesn't fit the mold: A pertussis-like toxin with altered specificity.
 

Author(s): Chen Chen, Joseph T Barbieri

Journal: J. Biol. Chem.. 2017 09;292(36):15159-15160.

 

Bacterial toxins introduce protein modifications such as ADP-ribosylation to manipulate host cell signaling and physiology. Several general mechanisms for toxin function have been established, but the extent to which previously uncharacterized toxins utilize these mechanisms is unknown. ...

Last Updated: 31 Dec 1969

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Epidemiological Characteristics and Risk Factors of the Pertussis in Infants < 12 Months of Age in Tianjin, China.
 

Author(s): Hai Tao Huang, Zhi Gang Gao, Yong Liu, Li Juan Wang, Yan Ping Liu, Ying Zhang

Journal: Biomed. Environ. Sci.. 2017 Jul;30(7):545-548.

 

The epidemiologic characteristics of 631 infant pertussis cases < 12 months, which accounted for 57.42% of the total cases, were analyzed by descriptive epidemiology in Tianjin, between 2010 and 2015. The incidence of infants was 104.66/100,000, which was 118 times higher than in ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pertussis" returned 92 free, full-text review articles on human participants. First 3 results:

The importance of Bordetella pertussis strains which do not produce virulence factors in the epidemiology of pertussis.
 

Author(s): Maciej Polak, Anna Lutyńska

Journal:

 

Bordetella pertussis strains, which have lost the ability to produce antigens, such as pertactin - Prn, pertussis toxin - Ptx, filamentous haemagglutinin - FHA, fimbriae type 2 and 3 - Fim 2 and 3, tracheal colonization factor - TcfA, have recently been isolated in countries with ...

Last Updated: 31 Dec 1969

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Live pertussis vaccines: will they protect against carriage and spread of pertussis?
 

Author(s): C Locht

Journal: Clin. Microbiol. Infect.. 2016 Dec;22 Suppl 5():S96-S102.

 

Pertussis is a severe respiratory disease that can be fatal in young infants. Its main aetiological agent is the Gram-negative micro-organism Bordetella pertussis. Vaccines against the disease have been in use since the 1950s, and global vaccination coverage has now reached more than ...

Last Updated: 31 Dec 1969

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Adverse events following primary and secondary immunisation with whole-cell pertussis: a systematic review protocol.
 

Author(s): Jenna Patterson, Benjamin M Kagina, Michael Gold, Gregory D Hussey, Rudzani Muloiwa

Journal:

 

Pertussis is a contagious respiratory illness caused by the bacterium Bordetella pertussis. Two types of vaccines are currently available against the disease: whole-cell pertussis (wP) and acellular pertussis (aP). With the shift of high-income countries from wP to aP as a result ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Feasibility of Pertussis Immunization in a Canadian Emergency Department
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 17 Oct 2017

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Pertussis Immunization During Pregnancy: Effect in Term and Preterm Infants
 

Status: Recruiting

Condition Summary: Pertussis

 

Last Updated: 29 Jul 2015

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Pertussis Immunization Programs in Low Income Countries
 

Status: Recruiting

Condition Summary: Bordetella Pertussis, Whooping Cough

 

Last Updated: 20 Dec 2017

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