West nile virus

Common Name(s)

West nile virus

West Nile Virus is an infectious disease spread by infected mosquitoes. Those infected typically have no symptoms or mild symptoms, whichcan include fever, headache, body aches, skin rash, and swollen lymph glands. These symptoms can last a few days to several weeks. West Nile Virus can be threatening, however, if the virus enters the brain, which can cause encephalitis or meningitis. Encephalitis is inflammation of the brain and meningitis is inflammation of the lining that covers the brain and spinal cord. Severe symptoms of West Nile virus include a severe headache, fever, disorientation, or sudden weakness.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "West nile virus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "West nile virus" returned 769 free, full-text research articles on human participants. First 3 results:

Detection of West Nile Virus RNA in patients with meningitis in Podlaskie Province.
 

Author(s): Piotr Czupryna, Jowita Niczyporuk, Elzbieta Samorek-Salamonowicz, Anna Moniuszko, Justyna Dunaj, Joanna Zajkowska, SÅ‚awomir A Pancewicz

Journal: Przegl Epidemiol. 2014 ;68(1):17-20, 109-11.

 

The aim of the study was the detection of WNV RNA in cerebrospinal fluid of patients with lymphocytic meningitis.

Last Updated: 9 Jul 2014

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West nile virus and other arboviral diseases - United States, 2013.
 

Author(s): Nicole P Lindsey, Jennifer A Lehman, J Erin Staples, Marc Fischer,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Jun;63(24):521-6.

 

Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes and ticks. West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease in the United States. However, several other arboviruses also cause sporadic ...

Last Updated: 19 Jun 2014

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Structural proteins of West Nile virus are a major determinant of infectious particle production and fitness in astrocytes.
 

Author(s): Katherine L Hussmann, Rianna Vandergaast, Kang Zheng, Lisa I Hoover, Brenda L Fredericksen

Journal: J. Gen. Virol.. 2014 Sep;95(Pt 9):1991-2003.

 

The molecular basis for the increased resistance of astrocytes to a non-neuropathogenic strain of West Nile virus (WNV), WNV-MAD78, compared with the neuropathogenic strain WNV-NY remains unclear. Here, we demonstrated that the reduced susceptibility of astrocytes to WNV-MAD78 is ...

Last Updated: 19 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "West nile virus" returned 62 free, full-text review articles on human participants. First 3 results:

Current trends in West Nile virus vaccine development.
 

Author(s): Ian J Amanna, Mark K Slifka

Journal: Expert Rev Vaccines. 2014 May;13(5):589-608.

 

West Nile virus (WNV) is a mosquito-borne flavivirus that has become endemic in the United States. From 1999-2012, there have been 37088 reported cases of WNV and 1549 deaths, resulting in a 4.2% case-fatality rate. Despite development of effective WNV vaccines for horses, there is ...

Last Updated: 11 Apr 2014

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B cell response and mechanisms of antibody protection to West Nile virus.
 

Author(s): S Kyle Austin, Kimberly A Dowd

Journal:

 

West Nile virus (WNV) has become the principal cause of viral encephalitis in North America since its introduction in New York in 1999. This emerging virus is transmitted to humans via the bite of an infected mosquito. While there have been several candidates in clinical trials, there ...

Last Updated: 5 Mar 2014

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Clinical manifestations and outcomes of West Nile virus infection.
 

Author(s): James J Sejvar

Journal:

 

Since the emergence of West Nile virus (WNV) in North America in 1999, understanding of the clinical features, spectrum of illness and eventual functional outcomes of human illness has increased tremendously. Most human infections with WNV remain clinically silent. Among those persons ...

Last Updated: 10 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 1 Trial of Inactivated West Nile Virus Vaccine
 

Status: Not yet recruiting

Condition Summary: West Nile Viral Infection

 

Last Updated: 22 Jan 2015

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