West nile virus

Common Name(s)

West nile virus

West Nile Virus is an infectious disease spread by infected mosquitoes. Those infected typically have no symptoms or mild symptoms, whichcan include fever, headache, body aches, skin rash, and swollen lymph glands. These symptoms can last a few days to several weeks. West Nile Virus can be threatening, however, if the virus enters the brain, which can cause encephalitis or meningitis. Encephalitis is inflammation of the brain and meningitis is inflammation of the lining that covers the brain and spinal cord. Severe symptoms of West Nile virus include a severe headache, fever, disorientation, or sudden weakness.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "West nile virus" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "West nile virus" returned 855 free, full-text research articles on human participants. First 3 results:

A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations.
 

Author(s): Neal Van Hoeven, Sharvari Waghmare Joshi, Ghislain Ismael Nana, Angela Bosco-Lauth, Christopher Fox, Richard A Bowen, David E Clements, Timothy Martyak, D Elliot Parks, Susan Baldwin, Steven G Reed, Rhea N Coler

Journal:

 

West Nile virus (WNV) is a mosquito-transmitted member of the Flaviviridae family that has emerged in recent years to become a serious public health threat. Given the sporadic nature of WNV epidemics both temporally and geographically, there is an urgent need for a vaccine that can ...

Last Updated: 23 Feb 2016

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Human MicroRNA miR-532-5p Exhibits Antiviral Activity against West Nile Virus via Suppression of Host Genes SESTD1 and TAB3 Required for Virus Replication.
 

Author(s): Andrii Slonchak, Rory P Shannon, Gabor Pali, Alexander A Khromykh

Journal:

 

West Nile virus (WNV) is a mosquito-transmitted flavivirus that naturally circulates between mosquitos and birds but can also infect humans, causing severe neurological disease. The early host response to WNV infection in vertebrates primarily relies on the type I interferon pathway; ...

Last Updated: 12 Feb 2016

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Concurrent Outbreaks of St. Louis Encephalitis Virus and West Nile Virus Disease - Arizona, 2015.
 

Author(s): Heather Venkat, Elisabeth Krow-Lucal, Morgan Hennessey, Jefferson Jones, Laura Adams, Marc Fischer, Tammy Sylvester, Craig Levy, Kirk Smith, Lydia Plante, Kenneth Komatsu, J Erin Staples, Susan Hills

Journal:

 

St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) are closely related mosquito-borne flaviviruses that can cause outbreaks of acute febrile illness and neurologic disease. Both viruses are endemic throughout much of the United States and have the same Culex species mosquito ...

Last Updated: 15 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "West nile virus" returned 80 free, full-text review articles on human participants. First 3 results:

The challenge of West Nile virus in Europe: knowledge gaps and research priorities.
 

Author(s): A Rizzoli, M A Jimenez-Clavero, L Barzon, P Cordioli, J Figuerola, P Koraka, B Martina, A Moreno, N Nowotny, N Pardigon, N Sanders, S Ulbert, A Tenorio

Journal:

 

West Nile virus (WNV) is continuously spreading across Europe, and other continents, i.e. North and South America and many other regions of the world. Despite the overall sporadic nature of outbreaks with cases of West Nile neuroinvasive disease (WNND) in Europe, the spillover events ...

Last Updated: 1 Jun 2015

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The global ecology and epidemiology of West Nile virus.
 

Author(s): Caren Chancey, Andriyan Grinev, Evgeniya Volkova, Maria Rios

Journal: Biomed Res Int. 2015 ;2015():376230.

 

Since its initial isolation in Uganda in 1937 through the present, West Nile virus (WNV) has become an important cause of human and animal disease worldwide. WNV, an enveloped virus of the genus Flavivirus, is naturally maintained in an enzootic cycle between birds and mosquitoes, ...

Last Updated: 13 Apr 2015

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Climate change impacts on West Nile virus transmission in a global context.
 

Author(s): Shlomit Paz

Journal: Philos. Trans. R. Soc. Lond., B, Biol. Sci.. 2015 Apr;370(1665):.

 

West Nile virus (WNV), the most widely distributed virus of the encephalitic flaviviruses, is a vector-borne pathogen of global importance. The transmission cycle exists in rural and urban areas where the virus infects birds, humans, horses and other mammals. Multiple factors impact ...

Last Updated: 17 Feb 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.