Wernicke-Korsakoff syndrome

Common Name(s)

Wernicke-Korsakoff syndrome

Wernicke-Korsakoff syndrome is a brain disorder due to thiamine deficiency that has been associated with both Wernicke's encephalopathy and Korsakoff syndrome. Wernicke's encephalopathy can result from alcohol abuse, dietary deficiencies, prolonged vomiting, eating disorders, or the effects of chemotherapy. Korsakoff's amnesic syndrome is a memory disorder that is associated with alcoholism and involvement of the heart, vascular, and nervous system. Although these conditions may appear to be two different disorders, they are generally considered to be different stages of Wernicke-Korsakoff syndrome. Wernicke's encephalopathy represents the "acute" phase and Korsakoff's amnesic syndrome represents the "chronic" phase.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wernicke-Korsakoff syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wernicke-Korsakoff syndrome" returned 18 free, full-text research articles on human participants. First 3 results:

Beyond alcoholism: Wernicke-Korsakoff syndrome in patients with psychiatric disorders.
 

Author(s): Laurie M McCormick, Judith R Buchanan, Obiora E Onwuameze, Ronald K Pierson, Sergio Paradiso

Journal: Cogn Behav Neurol. 2011 Dec;24(4):209-16.

 

Wernicke encephalopathy and Korsakoff syndrome (the combined disorder is named Wernicke-Korsakoff syndrome [WKS]) are preventable, life-threatening neuropsychiatric syndromes resulting from thiamine deficiency. WKS has historically been associated with alcoholism; more recently, it ...

Last Updated: 13 Dec 2011

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Wernicke-Korsakoff syndrome in the course of thyrotoxicosis - a case report.
 

Author(s): Joanna Wierzbicka-Chmiel, Krzysztof Wierzbicki, Dariusz Kajdaniuk, Ryszard Sędziak, Bogdan Marek

Journal: Endokrynol Pol. 2011 ;62(2):178-80.

 

Wernicke-Korsakoff syndrome (also called Wernicke's encephalopathy) is a potentially fatal, neuropsychiatric syndrome caused most frequently by thiamine deficiency. The three classic symptoms found together are confusion, ataxia and eyeball manifestations. Memory disturbances can ...

Last Updated: 29 Apr 2011

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[A case of Wernicke-Korsakoff syndrome who succeeded in returning to work despite the sequelae].
 

Author(s): Shuji Soeda

Journal: Sangyo Eiseigaku Zasshi. 2009 Jul;51(4):43-5.

 

Last Updated: 18 Sep 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wernicke-Korsakoff syndrome" returned 4 free, full-text review articles on human participants. First 3 results:

Brain and behavioral pathology in an animal model of Wernicke's encephalopathy and Wernicke-Korsakoff Syndrome.
 

Author(s): Ryan P Vetreno, Raddy L Ramos, Steven Anzalone, Lisa M Savage

Journal: Brain Res.. 2012 Feb;1436():178-92.

 

Animal models provide the opportunity for in-depth and experimental investigation into the anatomical and physiological underpinnings of human neurological disorders. Rodent models of thiamine deficiency have yielded significant insight into the structural, neurochemical and cognitive ...

Last Updated: 23 Jan 2012

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Neuroimaging of the Wernicke-Korsakoff syndrome.
 

Author(s): Edith V Sullivan, Adolf Pfefferbaum

Journal: Alcohol Alcohol.. ;44(2):155-65.

 

Presented is the neuroradiological signature of acute Wernicke's encephalopathy (WE), derived from different types of magnetic resonance imaging (MRI) sequences. WE results from thiamine depletion, and its most typical antecedent is chronic alcohol dependence. Brain regions observed ...

Last Updated: 24 Feb 2009

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Wernicke-Korsakoff syndrome associated with hyperemesis gravidarum.
 

Author(s): Chang-Kyoon Yoon, Moo-Hwan Chang, Dong-Cho Lee

Journal: Korean J Ophthalmol. 2005 Sep;19(3):239-42.

 

The authors hereby describe a case of Wernicke-Korsakoff syndrome with accompanying ocular findings that is caused by hyperernesis gravidarum.

Last Updated: 7 Oct 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

From Uncomplicated Alcoholism to Korsakoff's Syndrome
 

Status: Recruiting

Condition Summary: Alcoholism; Alcohol Amnestic Disorder

 

Last Updated: 8 Apr 2014

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