Wells syndrome

Common Name(s)

Wells syndrome

Wells syndrome is a rare eosinophilic disorder characterized by itchy, burning, red, and inflamed areas on the skin often on the lower arm or leg. The lesions may be single or multiple. They are usually red at first (looking like cellulitis) then change to brown red, to blue gray, then greenish gray. The lesions are usually painful and are sometimes associated with a fever. They typically heal without scarring within weeks to months; however they often recur. The cause of Wells syndrome is unknown; but some researchers think that Wells syndrome is an autoimmune reaction.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wells syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wells syndrome" returned 34 free, full-text research articles on human participants. First 3 results:

Renal failure in Hay-Wells syndrome.
 

Author(s): Dhanya Mohan, Dileep K Sugathan, Mohammed Railey, Mona Alrukhaimi

Journal: Saudi J Kidney Dis Transpl. 2013 Nov;24(6):1214-6.

 

Ectodermal dysplasia (ED) is a group of disorders involving developmental defects of the ectodermal structures, with abnormalities in the skin, hair, nails and sweat glands. Ankyloblepharon - ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is ...

Last Updated: 15 Nov 2013

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Gigantic erythematous plaques with violaceous oedematous borders: a quiz. Wells' syndrome.
 

Author(s): Norma Mechow, Ioana Cosgarea, Edward Ogwang, Ingolf Franke, Harald P Gollnick, Sven R Quist

Journal: Acta Derm. Venereol.. 2013 Nov;93(6):763, 764.

 

Last Updated: 23 Oct 2013

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Renal and thyroid amyloidosis secondary tocryopyrin-associated periodic syndrome(Muckle-Wells syndrome) (NLRP3 mutation).
 

Author(s): Luis Bolaños, Juan M Mosquera-Reboredo, Mercedes Cao, Tamara Ferreiro, Beatriz Veleiro, Francisco Valdés, Eduardo Vázquez-Martul

Journal: Nefrologia. 2013 ;33(2):266-71.

 

Last Updated: 20 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wells syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

[Biological and clinical aspects of Muckle-Wells syndrome].
 

Author(s): Tetsuo Kubota, Ryuji Koike

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2007 Apr;30(2):114-22.

 

Muckle-Wells syndrome (MWS), as well as familial cold autoinflammatory syndrome (FCAS) and chronic infantile neurological cutaneous and articular syndrome (CINCA), arises from a missense mutation in the CIAS1 gene. Current progress of biology revealed that NALP3, a protein coded by ...

Last Updated: 2 May 2007

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Eosinophilic cellulitis (Wells' syndrome) as a cutaneous reaction to the administration of adalimumab.
 

Author(s): P Boura, A Sarantopoulos, I Lefaki, P Skendros, P Papadopoulos

Journal: Ann. Rheum. Dis.. 2006 Jun;65(6):839-40.

 

Last Updated: 15 May 2006

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
 

Status: Recruiting

Condition Summary: Cryopyrin-associated Periodic Syndromes; Familial Cold Autoinflammatory Syndrome; Muckle-Wells Syndrome; Neonatal Onset Multisystem Inflammatory Disease

 

Last Updated: 25 Aug 2014

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Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients
 

Status: Recruiting

Condition Summary: Cryopyrin-associated Periodic Syndromes (CAPS); Familial Cold Autoinflam Syn (FCAS); Muckle-wells Syn (MWS); Neonatal Onset Multisystem Inflam Disease (NOMID)

 

Last Updated: 6 Mar 2014

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Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics
 

Status: Recruiting

Condition Summary: Periodic Disease

 

Last Updated: 14 Mar 2014

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