Wells syndrome

Common Name(s)

Wells syndrome

Wells syndrome is a rare eosinophilic disorder characterized by itchy, burning, red, and inflamed areas on the skin often on the lower arm or leg. The lesions may be single or multiple. They are usually red at first (looking like cellulitis) then change to brown red, to blue gray, then greenish gray. The lesions are usually painful and are sometimes associated with a fever. They typically heal without scarring within weeks to months; however they often recur. The cause of Wells syndrome is unknown; but some researchers think that Wells syndrome is an autoimmune reaction.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wells syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wells syndrome" returned 37 free, full-text research articles on human participants. First 3 results:

Recurrent paraneoplastic wells syndrome in a patient with metastatic renal cell cancer.
 

Author(s): Anand Rajpara, Ana Liolios, Garth Fraga, Joseph Blackmon

Journal:

 

A 58-year-old man with a history of hyperlipidemia and hypertension presented to the dermatology clinic with a 3-month history of a sudden onset, progressively worsening pruritic eruption involving the torso and extremities. Prior treatment included azithromycin and oral and intramuscular ...

Last Updated: 20 Jun 2014

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Syndrome in question. Hay-Wells syndrome.
 

Author(s): Vanessa Mello Tonolli, Hamilton Ometto Stolf, Cláudio Sampieri Tonello, Rafaelle Batistella Pires, Luciana Patricia Fernandes Abbade

Journal: An Bras Dermatol. ;89(2):363-4.

 

Hay-Wells syndrome or AEC (Ankyloblepharon, Ectodermal dysplasia and Cleft lip and palate syndrome) is a rare ectodermal disorder. The treatment is aimed to prevent clinical complications. We describe the case of a four-month old male patient with erosions on the scalp, trunk and ...

Last Updated: 28 Apr 2014

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Renal failure in Hay-Wells syndrome.
 

Author(s): Dhanya Mohan, Dileep K Sugathan, Mohammed Railey, Mona Alrukhaimi

Journal: Saudi J Kidney Dis Transpl. 2013 Nov;24(6):1214-6.

 

Ectodermal dysplasia (ED) is a group of disorders involving developmental defects of the ectodermal structures, with abnormalities in the skin, hair, nails and sweat glands. Ankyloblepharon - ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is ...

Last Updated: 15 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wells syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

[Biological and clinical aspects of Muckle-Wells syndrome].
 

Author(s): Tetsuo Kubota, Ryuji Koike

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2007 Apr;30(2):114-22.

 

Muckle-Wells syndrome (MWS), as well as familial cold autoinflammatory syndrome (FCAS) and chronic infantile neurological cutaneous and articular syndrome (CINCA), arises from a missense mutation in the CIAS1 gene. Current progress of biology revealed that NALP3, a protein coded by ...

Last Updated: 2 May 2007

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Eosinophilic cellulitis (Wells' syndrome) as a cutaneous reaction to the administration of adalimumab.
 

Author(s): P Boura, A Sarantopoulos, I Lefaki, P Skendros, P Papadopoulos

Journal: Ann. Rheum. Dis.. 2006 Jun;65(6):839-40.

 

Last Updated: 15 May 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
 

Status: Recruiting

Condition Summary: Cryopyrin-associated Periodic Syndromes; Familial Cold Autoinflammatory Syndrome; Muckle-Wells Syndrome; Neonatal Onset Multisystem Inflammatory Disease

 

Last Updated: 25 Aug 2014

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Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients
 

Status: Recruiting

Condition Summary: Cryopyrin-associated Periodic Syndromes (CAPS); Familial Cold Autoinflam Syn (FCAS); Muckle-wells Syn (MWS); Neonatal Onset Multisystem Inflam Disease (NOMID)

 

Last Updated: 6 Mar 2014

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Living Well Project for Persons With AIDS
 

Status: Recruiting

Condition Summary: Acquired Immunodeficiency Syndrome (AIDS)

 

Last Updated: 27 Aug 2014

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