Waterhouse–Friderichsen syndrome

Common Name(s)

Waterhouse–Friderichsen syndrome

WaterhouseÐFriderichsen syndrome is adrenal gland failure due to bleeding into the adrenal gland. It is caused by severe meningococcal infection or other severe, bacterial infection. Symptoms include acute adrenal gland insufficiency, and profound shock.  Most patients with this condition are children, although adults may rarely be affected.  It is deadly if not treated immediately.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Waterhouse–Friderichsen syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Waterhouse–Friderichsen syndrome" returned 14 free, full-text research articles on human participants. First 3 results:

[Puerperal septic shock due to beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome].
 

Author(s): Stanley de Almeida Araújo, Ana Maria Arruda Lana, Paula Piedade Garcia, Pérsio Godoy

Journal: Rev. Soc. Bras. Med. Trop.. ;42(1):73-6.

 

An exceptional case of a 15-year-old puerpera with septic shock caused by Group A beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome is reported. The findings were observed at the necropsy. The characteristics of the diagnosis, pathogenesis and evolution of this puerperal ...

Last Updated: 16 Mar 2009

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Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children.
 

Author(s): Patricia V Adem, Christopher P Montgomery, Aliya N Husain, Tracy K Koogler, Valerie Arangelovich, Michel Humilier, Susan Boyle-Vavra, Robert S Daum

Journal: N. Engl. J. Med.. 2005 Sep;353(12):1245-51.

 

Staphylococcus aureus has increasingly been recognized as a cause of severe invasive illness. We describe three children who died at our institution after rapidly progressive clinical deterioration from this infection, with necrotizing pneumonia and multiple-organ-system involvement. ...

Last Updated: 22 Sep 2005

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Waterhouse-Friderichsen syndrome as a result of non-meningococcal infection.
 

Author(s): D Hamilton, M D Harris, J Foweraker, G A Gresham

Journal: J. Clin. Pathol.. 2004 Feb;57(2):208-9.

 

Waterhouse-Friderichsen syndrome--massive adrenal haemorrhage in the setting of overwhelming clinical sepsis--is usually taken at necropsy to indicate meningococcal infection, and may be the only evidence of this pathogen. This report describes three fatal cases of the syndrome in ...

Last Updated: 28 Jan 2004

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Reviews from the PubMed Database

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The terms "Waterhouse–Friderichsen syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.