Waterhouse–Friderichsen syndrome

Common Name(s)

Waterhouse–Friderichsen syndrome

WaterhouseÐFriderichsen syndrome is adrenal gland failure due to bleeding into the adrenal gland. It is caused by severe meningococcal infection or other severe, bacterial infection. Symptoms include acute adrenal gland insufficiency, and profound shock.  Most patients with this condition are children, although adults may rarely be affected.  It is deadly if not treated immediately.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Waterhouse–Friderichsen syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Waterhouse–Friderichsen syndrome" returned 19 free, full-text research articles on human participants. First 3 results:

An autopsy case of pneumococcal Waterhouse-Friderichsen syndrome with possible functional asplenia/hyposplenia.
 

Author(s): Yukiko Hata, Takashi Chiba, Maki Ohtani, Shin Ishizawa, Naoki Nishida

Journal:

 

We report an autopsy case of rapid progressive Waterhouse-Friderichsen syndrome (WFS) associated with Streptococcus pneumonia infection in a previously healthy man. Although he once visited a hospital about 6 hours before death, the both physical and serological examination did not ...

Last Updated: 11 Aug 2015

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Waterhouse-friderichsen syndrome caused by invasive haemophilus influenzae type B infection in a previously healthy young man.
 

Author(s): S Shimizu, Y Tahara, T Atsumi, Y Imai, H Ueda, R Seo, N Higashibeppu, H Mima, K Yamazaki

Journal: Anaesth Intensive Care. 2010 Jan;38(1):214-5.

 

Last Updated: 2 Mar 2010

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[Puerperal septic shock due to beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome].
 

Author(s): Stanley de Almeida Araújo, Ana Maria Arruda Lana, Paula Piedade Garcia, Pérsio Godoy

Journal: Rev. Soc. Bras. Med. Trop.. ;42(1):73-6.

 

An exceptional case of a 15-year-old puerpera with septic shock caused by Group A beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome is reported. The findings were observed at the necropsy. The characteristics of the diagnosis, pathogenesis and evolution of this puerperal ...

Last Updated: 16 Mar 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Waterhouse–Friderichsen syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.