Wallerian degeneration

Common Name(s)

Wallerian degeneration

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wallerian degeneration" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wallerian degeneration" returned 33 free, full-text research articles on human participants. First 3 results:

Hyperintense signal in pyramidal tract neurons in postoperative brain tumor: wallerian degeneration or neoplastic dissemination?
 

Author(s): Ricardo Mendes Rogerio, José Luiz Pedroso, Acary Souza Bulle Oliveira, Lázaro Luis Faria do Amaral

Journal: Arq Neuropsiquiatr. 2013 Nov;71(11):907-8.

 

Last Updated: 7 Jan 2014

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MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling.
 

Author(s): Catherine Evans, Simon J Cook, Michael P Coleman, Jonathan Gilley

Journal:

 

Wallerian degeneration is delayed when sufficient levels of proteins with NMNAT activity are maintained within axons after injury. This has been proposed to form the basis of 'slow Wallerian degeneration' (Wld (S)), a neuroprotective phenotype conferred by an aberrant fusion protein, ...

Last Updated: 14 Oct 2013

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Natural history and prognostic value of corticospinal tract Wallerian degeneration in intracerebral hemorrhage.
 

Author(s): Chitra Venkatasubramanian, Jonathan T Kleinman, Nancy J Fischbein, Jean-Marc Olivot, Alisa D Gean, Irina Eyngorn, Ryan W Snider, Michael Mlynash, Christine A C Wijman

Journal:

 

The purpose of this study was to define the incidence, imaging characteristics, natural history, and prognostic implication of corticospinal tract Wallerian degeneration (CST-WD) in spontaneous intracerebral hemorrhage (ICH) using serial MR imaging.

Last Updated: 5 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wallerian degeneration" returned 2 free, full-text review articles on human participants. First 3 results:

Similarities between inherited demyelinating neuropathies and Wallerian degeneration: an old repair program may cause myelin and axon perturbation under nonlesion conditions.
 

Author(s): Rudolf Martini, Dennis Klein, Janos Groh

Journal: Am. J. Pathol.. 2013 Sep;183(3):655-60.

 

Wallerian degeneration (WD) and inherited demyelinating neuropathies of the Charcot-Marie-Tooth type 1 (CMT1) appear to represent completely distinct events. CMT1-like diseases are chronic disorders of peripheral nerves that are genetically caused and lead to secondary neurodegenerative ...

Last Updated: 26 Aug 2013

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Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury.
 

Author(s): Andrew D Gaudet, Phillip G Popovich, Matt S Ramer

Journal:

 

In this review, we first provide a brief historical perspective, discussing how peripheral nerve injury (PNI) may have caused World War I. We then consider the initiation, progression, and resolution of the cellular inflammatory response after PNI, before comparing the PNI inflammatory ...

Last Updated: 29 Sep 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Focal Cortical Atrophy After Myocardial Internal Capsule
 

Status: Recruiting

Condition Summary: Ischemic Stroke Involving Corticospinal Tract.

 

Last Updated: 22 Jul 2014

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