Vulvar cancer

Common Name(s)

Vulvar cancer

Vulvar cancer is the abnormal growth of cells of the vulva, which is part of the female reproductive system and includes the vaginal lips, clitoris, and part of the vagina.  Symptoms of vulvar cancer may consist of a lump (mass), itching, or unusual bleeding.  Though the exact cause of this cancer is unknown, older women and those who have human papillomavirus have a higher chance of developing vulvar cancer.  Treatment may include laser therapy, surgery, chemotherapy, or radiation therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vulvar cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vulvar cancer" returned 45 free, full-text research articles on human participants. First 3 results:

Subtypes of cytotoxic lymphocytes and natural killer cells infiltrating cancer nests correlate with prognosis in patients with vulvar squamous cell carcinoma.
 

Author(s): Jacek Jan Sznurkowski, Anton Zawrocki, Wojciech Biernat

Journal: Cancer Immunol. Immunother.. 2014 Mar;63(3):297-303.

 

Adaptive immune effectors do not influence prognosis in vulvar squamous cell carcinoma (vSCC). Therefore, we tried to clarify the prognostic role of innate immunity and granzyme B-dependent cytotoxicity as defined by intratumoral infiltrates of natural killer cells (CD56+) and lymphocytes ...

Last Updated: 19 Feb 2014

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Groin recurrence in patients with early vulvar cancer following superficial inguinal node dissection.
 

Author(s): Ahmad El Afandy, Hussein Soliman, Magdy El Sherbiny, Hatem Abo Elkasem

Journal: J Egypt Natl Canc Inst. 2013 Sep;25(3):121-4.

 

To investigate the causes of groin recurrence in patients with vulval cancer who previously had negative nodes following superficial inguinal node dissection (SIND).

Last Updated: 12 Aug 2013

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Electrochemotherapy can be used as palliative treatment in patients with repeated loco-regional recurrence of squamous vulvar cancer: a preliminary study.
 

Author(s): Anna Myriam Perrone, Andrea Galuppi, Simona Cima, Federica Pozzati, Alessandra Arcelli, Annalisa Cortesi, Martina Procaccini, Alice Pellegrini, Claudio Zamagni, Pierandrea De Iaco

Journal: Gynecol. Oncol.. 2013 Sep;130(3):550-3.

 

Electrochemotherapy (ECT) is an attractive treatment for solid cutaneous tumours with a good response rate (55-92%). No studies have evaluated ECT performed in vulvar cancer. The aim of our study was to evaluate the safety, local tumour efficacy and relief of symptoms of ECT treatment ...

Last Updated: 19 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vulvar cancer" returned 5 free, full-text review articles on human participants. First 3 results:

Late recurrence of sigmoid carcinoma mimicking primary vulvar cancer: case report and review of the literature.
 

Author(s): Emre Pabuccu, Harun Egemen Tolunay, Evren Kocbulut, Salih Taskın, Fırat Ortac, Ayse Sertcelik, Aysegul Sasmaz, Berna Savas

Journal: Int J Clin Exp Pathol. 2012 ;5(6):609-13.

 

To demonstrate a unique case report about late and isolated vulvar metastasis of sigmoid adeno-carcinoma with review of the literature.

Last Updated: 5 Sep 2012

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[Current treatments of vulvar cancer].
 

Author(s): P Mathevet

Journal: J Gynecol Obstet Biol Reprod (Paris). 2012 Oct;41(6):519-25.

 

Vulvar cancers are rare genital tumors. Their etiology is better understood. The management of these tumors has benefitted from recent therapeutic advances that decrease the morbidity of the treatments. Surgery is still the major curative option. But the limitation of the vulvar resections ...

Last Updated: 26 Sep 2012

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Sentinel lymph node biopsy in the management of vulvar carcinoma, cervical cancer, and endometrial cancer.
 

Author(s): Oliver Zivanovic, Fady Khoury-Collado, Nadeem R Abu-Rustum, Mary L Gemignani

Journal: Oncologist. 2009 Jul;14(7):695-705.

 

The treatment of gynecologic malignancies can include surgery, systemic therapy, and radiation. Depending on the primary site of disease and the extent of the disease, these treatment strategies are applied alone or in combination. Trends over the past few decades have concentrated ...

Last Updated: 31 Jul 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Bioimpedance Spectroscopy in Detecting Lower-Extremity Lymphedema in Patients With Stage I, Stage II, Stage III, or Stage IV Vulvar Cancer Undergoing Surgery and Lymphadenectomy
 

Status: Recruiting

Condition Summary: Lymphedema; Perioperative/Postoperative Complications; Stage IA Vulvar Cancer; Stage IB Vulvar Cancer; Stage II Vulvar Cancer; Stage IIIA Vulvar Cancer; Stage IIIB Vulvar Cancer; Stage IIIC Vulvar Cancer; Stage IVA Vulvar Cancer; Stage IVB Vulvar Cancer

 

Last Updated: 15 Apr 2014

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Observation in Patients With Early-Stage Vulvar Cancer Following Surgery and/or Radiation Therapy
 

Status: Recruiting

Condition Summary: Long-term Effects Secondary to Cancer Therapy in Adults; Squamous Cell Carcinoma of the Vulva; Stage I Vulvar Cancer; Stage II Vulvar Cancer; Stage III Vulvar Cancer

 

Last Updated: 25 Mar 2014

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Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Carcinoma of the Vulva
 

Status: Recruiting

Condition Summary: Squamous Cell Carcinoma of the Vulva; Stage IIIA Vulvar Cancer; Stage IIIB Vulvar Cancer; Stage IIIC Vulvar Cancer; Stage IVA Vulvar Cancer

 

Last Updated: 25 Mar 2014

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