Vulvar cancer

Common Name(s)

Vulvar cancer

Vulvar cancer is the abnormal growth of cells of the vulva, which is part of the female reproductive system and includes the vaginal lips, clitoris, and part of the vagina.  Symptoms of vulvar cancer may consist of a lump (mass), itching, or unusual bleeding.  Though the exact cause of this cancer is unknown, older women and those who have human papillomavirus have a higher chance of developing vulvar cancer.  Treatment may include laser therapy, surgery, chemotherapy, or radiation therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vulvar cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vulvar cancer" returned 49 free, full-text research articles on human participants. First 3 results:

Targeting human papillomavirus to reduce the burden of cervical, vulvar and vaginal cancer and pre-invasive neoplasia: establishing the baseline for surveillance.
 

Author(s): Mari Nygård, Bo Terning Hansen, Joakim Dillner, Christian Munk, Kristján Oddsson, Laufey Tryggvadottir, Maria Hortlund, Kai-Li Liaw, Erik J Dasbach, Susanne Krüger Kjær

Journal:

 

Infection with high-risk human papillomavirus (HPV) is causally related to cervical, vulvar and vaginal pre-invasive neoplasias and cancers. Highly effective vaccines against HPV types 16/18 have been available since 2006, and are currently used in many countries in combination with ...

Last Updated: 7 Feb 2014

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Subtypes of cytotoxic lymphocytes and natural killer cells infiltrating cancer nests correlate with prognosis in patients with vulvar squamous cell carcinoma.
 

Author(s): Jacek Jan Sznurkowski, Anton Zawrocki, Wojciech Biernat

Journal: Cancer Immunol. Immunother.. 2014 Mar;63(3):297-303.

 

Adaptive immune effectors do not influence prognosis in vulvar squamous cell carcinoma (vSCC). Therefore, we tried to clarify the prognostic role of innate immunity and granzyme B-dependent cytotoxicity as defined by intratumoral infiltrates of natural killer cells (CD56+) and lymphocytes ...

Last Updated: 19 Feb 2014

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Groin recurrence in patients with early vulvar cancer following superficial inguinal node dissection.
 

Author(s): Ahmad El Afandy, Hussein Soliman, Magdy El Sherbiny, Hatem Abo Elkasem

Journal: J Egypt Natl Canc Inst. 2013 Sep;25(3):121-4.

 

To investigate the causes of groin recurrence in patients with vulval cancer who previously had negative nodes following superficial inguinal node dissection (SIND).

Last Updated: 12 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vulvar cancer" returned 5 free, full-text review articles on human participants. First 3 results:

Late recurrence of sigmoid carcinoma mimicking primary vulvar cancer: case report and review of the literature.
 

Author(s): Emre Pabuccu, Harun Egemen Tolunay, Evren Kocbulut, Salih Taskın, Fırat Ortac, Ayse Sertcelik, Aysegul Sasmaz, Berna Savas

Journal: Int J Clin Exp Pathol. 2012 ;5(6):609-13.

 

To demonstrate a unique case report about late and isolated vulvar metastasis of sigmoid adeno-carcinoma with review of the literature.

Last Updated: 5 Sep 2012

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[Current treatments of vulvar cancer].
 

Author(s): P Mathevet

Journal: J Gynecol Obstet Biol Reprod (Paris). 2012 Oct;41(6):519-25.

 

Vulvar cancers are rare genital tumors. Their etiology is better understood. The management of these tumors has benefitted from recent therapeutic advances that decrease the morbidity of the treatments. Surgery is still the major curative option. But the limitation of the vulvar resections ...

Last Updated: 26 Sep 2012

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Sentinel lymph node biopsy in the management of vulvar carcinoma, cervical cancer, and endometrial cancer.
 

Author(s): Oliver Zivanovic, Fady Khoury-Collado, Nadeem R Abu-Rustum, Mary L Gemignani

Journal: Oncologist. 2009 Jul;14(7):695-705.

 

The treatment of gynecologic malignancies can include surgery, systemic therapy, and radiation. Depending on the primary site of disease and the extent of the disease, these treatment strategies are applied alone or in combination. Trends over the past few decades have concentrated ...

Last Updated: 31 Jul 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Observation in Patients With Early-Stage Vulvar Cancer Following Surgery and/or Radiation Therapy
 

Status: Recruiting

Condition Summary: Long-term Effects Secondary to Cancer Therapy in Adults; Squamous Cell Carcinoma of the Vulva; Stage I Vulvar Cancer; Stage II Vulvar Cancer; Stage III Vulvar Cancer

 

Last Updated: 8 Aug 2014

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Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Carcinoma of the Vulva
 

Status: Recruiting

Condition Summary: Squamous Cell Carcinoma of the Vulva; Stage IIIA Vulvar Cancer; Stage IIIB Vulvar Cancer; Stage IIIC Vulvar Cancer; Stage IVA Vulvar Cancer

 

Last Updated: 25 Mar 2014

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Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer
 

Status: Recruiting

Condition Summary: Lymphedema; Stage IA Cervical Cancer; Stage IA Endometrial Carcinoma; Stage IA Vulvar Cancer; Stage IB Cervical Cancer; Stage IB Endometrial Carcinoma; Stage IB Vulvar Cancer; Stage II Endometrial Carcinoma; Stage II Vulvar Cancer; Stage IIA Cervical Cancer; Stage IIIA Vulvar Cancer; Stage IIIB Vulvar Cancer; Stage IIIC Vulvar Cancer; Stage IVB Vulvar Cancer

 

Last Updated: 7 Mar 2014

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