Vogt-Koyanagi-Harada syndrome

Common Name(s)

Vogt-Koyanagi-Harada syndrome

Vogt-Koyanagi-Harada syndrome is a condition that involves chronic inflammation of melanocytes, which are specialized cells that produce a pigment called melanin.  Melanin is the substance that gives skin, hair, and eyes their color.  Melanin is also found in the retina, where it plays a role in normal vision.  Individuals with Vogt-Koyanagi-Harada syndrome usually develop vision and hearing disturbances first, followed by signs of skin problems.  Research suggests this condition is an autoimmune disease.  Vogt-Koyanagi-Harada syndrome is more common in individuals with darker skin pigmentation including Asian, Middle Eastern, Hispanic, and Native American populations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vogt-Koyanagi-Harada syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vogt-Koyanagi-Harada syndrome" returned 47 free, full-text research articles on human participants. First 3 results:

TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
 

Author(s): Qin Xiang, Lu Chen, Shengping Hou, Jing Fang, Yan Zhou, Lin Bai, Yunjia Liu, Aize Kijlstra, Peizeng Yang

Journal:

 

TRAF5 and TRAF3IP2 have been reported to be associated with several autoimmune diseases. Behçet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome are two autoimmune uveitis entities whereby both genetic and environmental factors are thought to be involved.

Last Updated: 13 Jan 2014

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MIF gene polymorphisms confer susceptibility to Vogt-Koyanagi-Harada syndrome in a Han Chinese population.
 

Author(s): Chunxia Zhang, Shouli Liu, Shengping Hou, Bo Lei, Xiuyun Zheng, Xiang Xiao, Aize Kijlstra, Peizeng Yang

Journal:

 

The aim of the study was to determine the association of macrophage migration inhibitory factor (MIF) gene polymorphisms with Vogt-Koyanagi-Harada (VKH) syndrome.

Last Updated: 25 Nov 2013

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FGFR1OP tagSNP but not CCR6 polymorphisms are associated with Vogt-Koyanagi-Harada syndrome in Chinese Han.
 

Author(s): Xianglong Yi, Liping Du, Shengping Hou, Fuzhen Li, Yuanyuan Chen, Aize Kijlstra, Peizeng Yang

Journal:

 

Polymorphisms of the CC chemokine receptor 6 (CCR6) and FGFR10P tagSNP (locus close to CCR6) at 6q27 have recently been reported to be associated with the susceptibility to several immune-related diseases. This study was designed to determine the association of CCR6 and FGFR10P (tag)SNPs ...

Last Updated: 12 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vogt-Koyanagi-Harada syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.