Vogt-Koyanagi-Harada syndrome

Common Name(s)

Vogt-Koyanagi-Harada syndrome

Vogt-Koyanagi-Harada syndrome (VKH disease) is a condition that involves chronic inflammation of melanocytes, which are specialized cells that produce a pigment called melanin. Melanin is the substance that gives skin, hair, and eyes their color. Melanin is also found in the retina, where it plays a role in normal vision. People with VKH disease usually develop vision and hearing disturbances first, followed by signs of skin problems. The most common symptoms include headaches, panuveitis, vitiligo, hair loss (alopecia), and inner ear disturbances. Neurological symptoms may also occur. The exact cause of VKH disease is not well understood, but research suggests it is an autoimmune disease. It is more common in people with darker skin pigmentation including Asian, Middle Eastern, Hispanic, and Native American populations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vogt-Koyanagi-Harada syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vogt-Koyanagi-Harada syndrome" returned 63 free, full-text research articles on human participants. First 3 results:

Unusual case of vitiligo reversal in Vogt-Koyanagi-Harada syndrome.
 

Author(s): Praveen Subudhi, Zahiruddin Khan, B Nageswar Rao Subudhi, Silla Sitaram

Journal: Indian J Ophthalmol. 2017 09;65(9):867-868.

 

Last Updated: 31 Dec 1969

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Management of a rare presentation of Vogt-Koyanagi-Harada disease in human immunodeficiency virus/acquired immunodeficiency disease syndrome patient.
 

Author(s): D Priya, S Sudharshan, Jyotirmay Biswas

Journal: Indian J Ophthalmol. 2017 May;65(5):413-416.

 

Vogt-Koyanagi-Harada (VKH), a multisystem autoimmune bilateral panuveitis with systemic manifestations, is uncommon in immunocompromised patients such as human immunodeficiency virus (HIV)/acquired immunodeficiency disease syndrome (AIDS). We report a rare presentation of VKH in a ...

Last Updated: 31 Dec 1969

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[Pseudodiscs in chronic recurrent Vogt-Koyanagi-Harada syndrome].
 

Author(s): A Ghanem, E Seyed, A Rhafour, Z Hajji, A Berraho

Journal: J Fr Ophtalmol. 2016 Oct;39(8):731-732.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vogt-Koyanagi-Harada syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Positron emission tomography/computed tomography scan of Vogt-Koyanagi-Harada syndrome with associated autoimmune thyroid disease: A case report and literature review.
 

Author(s): Ke-Hao Huang, Ming-Cheng Tai, Lung-Chi Lee, Tzu-Heng Weng, Yi-Hao Chen, Li-Fan Lin, Jiann-Torng Chen, Da-Wen Lu, Ching-Long Chen

Journal: Medicine (Baltimore). 2018 Mar;97(9):e0047.

 

Vogt-Koyanagi-Harada (VKH) syndrome is a rare disease and could be associated with autoimmune thyroid disease (AITD). This report was aimed to investigate the utility of F-fludeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of VKH syndrome ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease
 

Status: Recruiting

Condition Summary: Vogt Koyanagi Harada Disease

 

Last Updated: 12 Jan 2018

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