Vitiligo

Common Name(s)

Vitiligo

Vitiligo is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. As a result, white patches appear on the skin in different parts of the body, and sometimes also on both the mucous membranes and the retina. The average age of onset is in the mid-20s.  It is generally considered to be an autoimmune disorder, and about 20-25 percent of people with vitiligo also have at least one other autoimmune disorder. In the absence of other conditions, vitiligo does not affect general health; however, concerns about appearance and ethnic identity are significant issues for many affected individuals. The exact cause of vitiligo is not known, but there are several different theories. There is strong evidence that people with vitiligo inherit a group of genes that make them susceptible to depigmentation. The main goal of treating vitiligo is to improve appearance; current treatment options include medication, surgery, and adjunctive therapies (used along with surgical or medical treatments).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vitiligo" for support, advocacy or research.

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American Vitiligo Research Foundation

American Vitiligo Research Foundation Inc. (AVRF) provides public awareness about vitiligo through dedicated work, education and counseling. We seek to make a difference worldwide to those afflicted by the disease, focusing on children and their families. We embrace diversity and encourage acceptance. The AVRF encourages higher ethical standards in research, and therefore supports finding a cure through alternatives to animal testing.

Last Updated: 14 Jan 2013

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Vitiligo Research Foundation (VR Foundation)

Firmly committed to curing Vitiligo, the VR Foundation is a disease-specific non-profit organization funding and fast-tracking medical research globally. Our mission is to accelerate the end of suffering for millions of people who suffer from vitiligo through research, support and education.

Last Updated: 21 Aug 2014

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Vitiligo Support International Inc.

Vitiligo Support International Inc. (VSI) is a patient driven 501 (c) (3) nonprofit organization, committed to supporting those affected by vitiligo, raising awareness, promoting research, and discussing effective treatments until a cure is found.

Last Updated: 30 Nov 2012

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vitiligo" for support, advocacy or research.

Logo
American Vitiligo Research Foundation

American Vitiligo Research Foundation Inc. (AVRF) provides public awareness about vitiligo through dedicated work, education and counseling. We seek to make a difference worldwide to those afflicted by the disease, focusing on children and their families. We embrace diversity and encourage acceptance. The AVRF encourages higher ethical standards in research, and therefore supports finding a cure through alternatives to animal testing.

http://www.avrf.org/

Last Updated: 14 Jan 2013

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Vitiligo Research Foundation (VR Foundation)

Firmly committed to curing Vitiligo, the VR Foundation is a disease-specific non-profit organization funding and fast-tracking medical research globally. Our mission is to accelerate the end of suffering for millions of people who suffer from vitiligo through research, support and education.

http://vrfoundation.org

Last Updated: 21 Aug 2014

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Vitiligo Support International Inc.

Vitiligo Support International Inc. (VSI) is a patient driven 501 (c) (3) nonprofit organization, committed to supporting those affected by vitiligo, raising awareness, promoting research, and discussing effective treatments until a cure is found.

https://www.vitiligosupport.org/front_page.cfm

Last Updated: 30 Nov 2012

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General Resources

Vitiligo Biobank

The Vitiligo BioBank is a non-profit, independent collection of biological samples and detailed associated data, designed to facilitate medical research into vitiligo, a devastating skin disease that is much neglected. Here at the Vitiligo Biob

Updated 18 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vitiligo" returned 426 free, full-text research articles on human participants. First 3 results:

Vitiligo or Vitiligo-like Hypopigmentation Associated with Imiquimod Treatment of Condyloma Acuminatum: Not a Casual Event.
 

Author(s): Fu-Quan Long, Li-Shi Zhao, Yi-Hong Qian

Journal: Chin. Med. J.. 2017 02;130(4):503-504.

 

Last Updated: 20 Feb 2017

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Vitiligo-specific instrument on quality of life - Brazilian Portuguese version.
 

Author(s): Juliana Catucci Boza, Natália Piccinini Giongo, Tania Ferreira Cestari

Journal: An Bras Dermatol. ;91(6):865-866.

 

Last Updated: 18 Jan 2017

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Knowledge, beliefs, and perceptions of Turkish vitiligo patients regarding their condition.
 

Author(s): Ilteris Oguz Topal, Hatice Duman, Ozgur Emek Kocaturk Goncu, Mustafa Durmuscan, Sule Gungor, Pelin Kuteyla Ulkumen

Journal: An Bras Dermatol. ;91(6):770-775.

 

Vitiligo is an acquired pigmentary skin disorder that affects 0.5% to 2.0% of the population.

Last Updated: 18 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vitiligo" returned 43 free, full-text review articles on human participants. First 3 results:

Association of protein tyrosine phosphatase, non-receptor type 22 +1858C→T polymorphism and susceptibility to vitiligo: Systematic review and meta-analysis.
 

Author(s): Silky Agarwal, Harish Changotra

Journal: Indian J Dermatol Venereol Leprol. ;83(2):183-189.

 

Protein tyrosine phosphatase, non-receptor type 22 gene, which translates to lymphoid tyrosine phosphatase, is considered to be a susceptibility gene marker associated with several autoimmune diseases. Several studies have demonstrated the association of protein tyrosine phosphatase, ...

Last Updated: 6 Feb 2017

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Dysfunction of Autophagy: A Possible Mechanism Involved in the Pathogenesis of Vitiligo by Breaking the Redox Balance of Melanocytes.
 

Author(s): Zhuhui Qiao, Xiuxiu Wang, Leihong Xiang, Chengfeng Zhang

Journal: Oxid Med Cell Longev. 2016 ;2016():3401570.

 

Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of functional melanocytes from the epidermis and follicular reservoir. Among multiple hypotheses which have been proposed in the pathogenesis of vitiligo, autoimmunity and oxidative stress-mediated toxicity ...

Last Updated: 26 Dec 2016

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Coexistence of erythema dyschromicum perstans and vitiligo: a case report and review of the literature.
 

Author(s): Funda Tamer

Journal: Acta Dermatovenerol Alp Pannonica Adriat. 2016 Dec;25(4):77-78.

 

Erythema dyschromicum perstans is a rare, chronic, pigmentary disorder with unknown etiology. It clinically presents with oval to round, gray, blue, or brown macules of various sizes. The etiology remains unknown; however, cobalt allergy, radio contrast media, intestinal parasites, ...

Last Updated: 23 Dec 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 8 Jun 2017

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Last Updated: 10 Nov 2016

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A Study of INCB018424 Phosphate Cream in Subjects With Vitiligo
 

Status: Recruiting

Condition Summary: Vitiligo

 

Last Updated: 2 Aug 2017

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