Van der Woude syndrome 2

Common Name(s)

Van der Woude syndrome 2

Van der Woude syndrome (VWS) is a dominantly inherited developmental disorder characterized by pits and/or sinuses of the lower lip, and cleft lip and/or cleft palate (CL/P, CP). It is the most common cleft syndrome. For a phenotypic description and a discussion of genetic heterogeneity of van der Woude syndrome, see VWS1 ({119300}). See also orofacial cleft-13 (OFC13; {613857}) for a susceptibility locus mapping to chromosome 1p33.
 

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Condition Specific Organizations

Following organizations serve the condition "Van der Woude syndrome 2" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

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The terms "Van der Woude syndrome 2" returned 2 free, full-text research articles on human participants. First 3 results:

Genetic heterogeneity and exclusion of a modifying locus at 17p11.2-p11.1 in Finnish families with van der Woude syndrome.
 

Author(s): F K Wong, H Koillinen, J Rautio, B T Teh, R Ranta, A Karsten, O Larson, S Linder-Aronson, J Huggare, C Larsson, J Kere

Journal: J. Med. Genet.. 2001 Mar;38(3):198-202.

 

Last Updated: 13 Apr 2001

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Linkage analysis in a large Brazilian family with van der Woude syndrome suggests the existence of a susceptibility locus for cleft palate at 17p11.2-11.1.
 

Author(s): A L SertiƩ, A V Sousa, S Steman, R C Pavanello, M R Passos-Bueno

Journal: Am. J. Hum. Genet.. 1999 Aug;65(2):433-40.

 

van der Woude syndrome (VWS), which has been mapped to 1q32-41, is characterized by pits and/or sinuses of the lower lip, cleft lip/palate (CL/P), cleft palate (CP), bifid uvula, and hypodontia (H). The expression of VWS, which has incomplete penetrance, is highly variable. Both the ...

Last Updated: 20 Aug 1999

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The terms "Van der Woude syndrome 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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