Uveal melanoma

Common Name(s)

Uveal melanoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveal melanoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveal melanoma" returned 427 free, full-text research articles on human participants. First 3 results:

PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma.
 

Author(s): Gülçin Gezgin, Sietse J Luk, Jinfeng Cao, Mehmet Dogrusöz, Dirk M van der Steen, Renate S Hagedoorn, Daniëlle Krijgsman, Pieter A van der Velden, Matthew G Field, Gregorius P M Luyten, Karoly Szuhai, J William Harbour, Ekaterina S Jordanova, Mirjam H M Heemskerk, Martine J Jager

Journal: JAMA Ophthalmol. 2017 Jun;135(6):541-549.

 

Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentially expressed antigen in melanoma), which can ...

Last Updated: 27 Apr 2017

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Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma.
 

Author(s): Eva Sipos, Kata Hegyi, Andrea Treszl, Zita Steiber, Gabor Mehes, Nikoletta Dobos, Klara Fodor, Gabor Olah, Lorant Szekvolgyi, Andrew V Schally, Gabor Halmos

Journal: Oncol. Rep.. 2017 Apr;37(4):1927-1934.

 

Uveal melanoma (UM) is the most common primary intraocular malignancy with a very poor prognosis. The most frequent chromosome aberration in UM is the monosomy of chromosome 3. Previously, we demonstrated that ~50% of UMs express type-I receptor for luteinizing hormone‑releasing ...

Last Updated: 28 Mar 2017

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The Long Non-Coding RNA RHPN1-AS1 Promotes Uveal Melanoma Progression.
 

Author(s): Linna Lu, Xiaoyu Yu, Leilei Zhang, Xia Ding, Hui Pan, Xuyang Wen, Shiqiong Xu, Yue Xing, Jiayan Fan, Shengfang Ge, He Zhang, Renbing Jia, Xianqun Fan

Journal:

 

Increasing evidence suggests that aberrant long non-coding RNAs (lncRNAs) are significantly correlated with the pathogenesis, development and metastasis of cancers. RHPN1 antisense RNA 1 (RHPN1-AS1) is a 2030-bp transcript originating from human chromosome 8q24. However, the role ...

Last Updated: 26 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveal melanoma" returned 40 free, full-text review articles on human participants. First 3 results:

Uveal Melanoma Cell Lines: Where do they come from? (An American Ophthalmological Society Thesis).
 

Author(s): Martine J Jager, J Antonio Bermudez Magner, Bruce R Ksander, Sander R Dubovy

Journal: Trans Am Ophthalmol Soc. 2016 Aug;114():T5.

 

To determine whether some of the most often used uveal melanoma cell lines resemble their original tumor.

Last Updated: 26 Dec 2016

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Update on Ophthalmic Oncology 2014: Retinoblastoma and Uveal Melanoma.
 

Author(s): Jasmine H Francis, Ariana M Levin, David H Abramson

Journal: Asia Pac J Ophthalmol (Phila). ;5(5):368-82.

 

The aim of this study was to review peer-reviewed articles on ophthalmic oncology (specifically retinoblastoma and uveal melanoma) published from January to December 2014.

Last Updated: 16 Sep 2016

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Metastatic disease from uveal melanoma: treatment options and future prospects.
 

Author(s): Richard D Carvajal, Gary K Schwartz, Tongalp Tezel, Brian Marr, Jasmine H Francis, Paul D Nathan

Journal: Br J Ophthalmol. 2017 Jan;101(1):38-44.

 

Uveal melanoma represents ∼85% of all ocular melanomas and up to 50% of patients develop metastatic disease. Metastases are most frequently localised to the liver and, as few patients are candidates for potentially curative surgery, this is associated with a poor prognosis. There ...

Last Updated: 30 Aug 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 25 May 2017

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Last Updated: 27 Sep 2011

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Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 4 May 2017

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