Uveal melanoma

Common Name(s)

Uveal melanoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveal melanoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveal melanoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveal melanoma" returned 410 free, full-text research articles on human participants. First 3 results:

Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma.
 

Author(s): Pierre L Triozzi, Susan Achberger, Wayne Aldrich, John W Crabb, Yogen Saunthararajah, Arun D Singh

Journal:

 

Epigenetic events mediated by methylation and histone modifications have been associated with the development of metastasis in patients with uveal melanoma. The role of epigenetic events mediated by microRNA (miR) is less clear. Tumor and plasma miR expression was examined in patients ...

Last Updated: 25 Jul 2016

Go To URL
Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma.
 

Author(s): Wei Dai, Jingfeng Zhou, Bei Jin, Jingxuan Pan

Journal:

 

Uveal melanoma (UM) is the most common intraocular malignancy in adults. Despite improvements in surgical, radiation and chemotherapy treatments, the overall survival of UM and prognosis remain poor. In the present study, we hypothesized that Sirtuin 1 and 2 (SIRT1/2), class III histone ...

Last Updated: 4 Mar 2016

Go To URL
Phase II Trial of Bevacizumab in Combination With Temozolomide as First-Line Treatment in Patients With Metastatic Uveal Melanoma.
 

Author(s): Sophie Piperno-Neumann, Alhassane Diallo, Marie-Christine Etienne-Grimaldi, François-Clément Bidard, Manuel Rodrigues, Corine Plancher, Pascale Mariani, Nathalie Cassoux, Didier Decaudin, Bernard Asselain, Vincent Servois

Journal: Oncologist. 2016 Mar;21(3):281-2.

 

In experimental models, bevacizumab suppressed in vitro growth and in vivo hepatic metastasis of ocular melanoma cells. Additional preclinical data suggested a potential benefit when combining bevacizumab with dacarbazine.

Last Updated: 11 Mar 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveal melanoma" returned 30 free, full-text review articles on human participants. First 3 results:

Clinical Management of Uveal and Conjunctival Melanoma.
 

Author(s): Elyse S Blum, Jessica Yang, Kimberly M Komatsubara, Richard D Carvajal

Journal: Oncology (Williston Park, N.Y.). 2016 Jan;30(1):29-32, 34-43, 48.

 

Ocular melanoma is a rare but potentially devastating malignancy arising from the melanocytes of the uveal tract, conjunctiva, or orbit; it represents less than 5% of all melanoma cases in the United States. The management of ocular melanoma varies depending on its anatomic origin, ...

Last Updated: 21 Jan 2016

Go To URL
Upcoming translational challenges for uveal melanoma.
 

Author(s): Nabil Amirouchene-Angelozzi, Marie Schoumacher, Marc-Henri Stern, Nathalie Cassoux, Laurence Desjardins, Sophie Piperno-Neumann, Olivier Lantz, Sergio Roman-Roman

Journal: Br. J. Cancer. 2015 Nov;113(9):1249-53.

 

The past few years have witnessed major advances in the understanding of the molecular landscape of uveal melanoma (UM). The discovery of a mutational background that is completely different from the one of skin melanoma has granted to UM a stand-alone status. The absence of effective ...

Last Updated: 4 Nov 2015

Go To URL
Uveal Melanoma UK National Guidelines.
 

Author(s): P Nathan, V Cohen, S Coupland, K Curtis, B Damato, J Evans, S Fenwick, L Kirkpatrick, O Li, E Marshall, K McGuirk, C Ottensmeier, N Pearce, S Salvi, B Stedman, P Szlosarek, N Turnbull,

Journal: Eur. J. Cancer. 2015 Nov;51(16):2404-12.

 

The United Kingdom (UK) uveal melanoma guideline development group used an evidence based systematic approach (Scottish Intercollegiate Guidelines Network (SIGN)) to make recommendations in key areas of uncertainty in the field including: the use and effectiveness of new technologies ...

Last Updated: 14 Oct 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 11 Jan 2017

Go to URL

Last Updated: 27 Sep 2011

Go to URL
Intermittent Selumetinib for Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 15 Dec 2016

Go to URL