Uveal melanoma

Common Name(s)

Uveal melanoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveal melanoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveal melanoma" returned 442 free, full-text research articles on human participants. First 3 results:

High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma.
 

Author(s): Haiming Xu, Jingwen Gong, Hui Liu

Journal:

 

The plasmacytoma variant translocation 1 gene (PVT1) plays an oncogenic role in the initiation and progression of multiple cancers. In this study, by using deep-sequencing data and follow-up data in the Cancer Genome Atlas-Uveal melanomas (TCGA-UVM), we assessed the association between ...

Last Updated: 31 Dec 1969

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Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p.
 

Author(s): Xiaoli Zheng, Hongwei Tang, Xiaofeng Zhao, Yamei Sun, Yanfang Jiang, Yonghua Liu

Journal:

 

Growing evidences indicated that Long noncoding RNAs (lncRNAs) played important roles in tumor initiation and progression. However, the function and mechnism of lncRNA ferritin heavy chain 1 pseudogene 3 (FTH1P3) remain unknown in uveal melanoma. We showed that the expression level ...

Last Updated: 31 Dec 1969

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Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.
 

Author(s): A Gordon Robertson, Juliann Shih, Christina Yau, Ewan A Gibb, Junna Oba, Karen L Mungall, Julian M Hess, Vladislav Uzunangelov, Vonn Walter, Ludmila Danilova, Tara M Lichtenberg, Melanie Kucherlapati, Patrick K Kimes, Ming Tang, Alexander Penson, Ozgun Babur, Rehan Akbani, Christopher A Bristow, Katherine A Hoadley, Lisa Iype, Matthew T Chang, , Andrew D Cherniack, Christopher Benz, Gordon B Mills, Roel G W Verhaak, Klaus G Griewank, Ina Felau, Jean C Zenklusen, Jeffrey E Gershenwald, Lynn Schoenfield, Alexander J Lazar, Mohamed H Abdel-Rahman, Sergio Roman-Roman, Marc-Henri Stern, Colleen M Cebulla, Michelle D Williams, Martine J Jager, Sarah E Coupland, Bita Esmaeli, Cyriac Kandoth, Scott E Woodman

Journal: Cancer Cell. 2017 Aug;32(2):204-220.e15.

 

Comprehensive multiplatform analysis of 80 uveal melanomas (UM) identifies four molecularly distinct, clinically relevant subtypes: two associated with poor-prognosis monosomy 3 (M3) and two with better-prognosis disomy 3 (D3). We show that BAP1 loss follows M3 occurrence and correlates ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveal melanoma" returned 45 free, full-text review articles on human participants. First 3 results:

Focus on cutaneous and uveal melanoma specificities.
 

Author(s): Charlotte Pandiani, Guillaume E Béranger, Justine Leclerc, Robert Ballotti, Corine Bertolotto

Journal: Genes Dev.. 2017 Apr;31(8):724-743.

 

Cutaneous melanoma (CM) and uveal melanoma (UM) derive from cutaneous and uveal melanocytes that share the same embryonic origin and display the same cellular function. However, the etiopathogenesis and biological behaviors of these melanomas are very different. CM and UM display ...

Last Updated: 31 Dec 1969

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Uveal Melanoma Treatment and Prognostication.
 

Author(s): Mehmet Dogrusöz, Martine J Jager, Bertil Damato

Journal: Asia Pac J Ophthalmol (Phila). ;6(2):186-196.

 

Approximately 90% of uveal melanoma develop in the choroid, with the remainder arising in the ciliary body or the iris. The treatment of uveal melanoma is aimed at conserving the eye and useful vision, and, if possible, preventing metastatic disease. Enucleation is now reserved for ...

Last Updated: 31 Dec 1969

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Uveal Melanoma: Identifying Immunological and Chemotherapeutic Targets to Treat Metastases.
 

Author(s): Martine J Jager, Mehmet Dogrusöz, Scott E Woodman

Journal: Asia Pac J Ophthalmol (Phila). ;6(2):179-185.

 

Uveal melanoma is an intraocular malignancy that, depending on its size and genetic make-up, may lead to metastases in up to 50% of cases. Currently, no therapy has been proven to improve survival. However, new therapies exploiting immune responses against metastases are being developed. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 4 Dec 2017

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Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 4 May 2017

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Last Updated: 27 Sep 2011

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