Typhus

Common Name(s)

Typhus

Typhus is a general term for a group of diseases passed on by lice, flea, tick, and other insect bites. Types of typhus include epidemic typhus, scrub typhus, murine typhus. Common symptoms of most typhus cases include fever, headache, muscle aches, rapid breathing, and rash. Typhus is uncommon in the United States and can be prevented by avoiding contact with rats and keeping pets treated for ticks and fleas. Usually typhus can be cured with antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Typhus" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Typhus" returned 385 free, full-text research articles on human participants. First 3 results:

Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus.
 

Author(s): In O Sun, Sung Hye Shin, A Young Cho, Hyun Ju Yoon, Mi Yok Chang, Kwang Young Lee

Journal:

 

The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) for acute kidney injury (AKI) in patients with scrub typhus.

Last Updated: 18 Apr 2017

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Significance of major international seaports in the distribution of murine typhus in Taiwan.
 

Author(s): Chi-Chien Kuo, Nicola Wardrop, Chung-Te Chang, Hsi-Chieh Wang, Peter M Atkinson

Journal:

 

International seaports are hotspots for disease invasion and pathogens can persist in seaports even after ports are abandoned. Transmitted by fleas infected by Rickettsia typhi, murine typhus, a largely neglected and easily misdiagnosed disease, is known to occur primarily in large ...

Last Updated: 6 Mar 2017

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Molecular and serological evidence of flea-associated typhus group and spotted fever group rickettsial infections in Madagascar.
 

Author(s): Rado J L Rakotonanahary, Alan Harrison, Alice N Maina, Ju Jiang, Allen L Richards, Minoarisoa Rajerison, Sandra Telfer

Journal:

 

Rickettsiae are obligate intracellular bacteria responsible for many febrile syndromes around the world, including in sub-Saharan Africa. Vectors of these pathogens include ticks, lice, mites and fleas. In order to assess exposure to flea-associated Rickettsia species in Madagascar, ...

Last Updated: 5 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Typhus" returned 18 free, full-text review articles on human participants. First 3 results:

Successful Treatment of Scrub Typhus-Associated Hemophagocytic Lymphohistiocytosis With Chloramphenicol: Report of 3 Pediatric Cases and Literature Review.
 

Author(s): Yong-Hai Zhou, Fang-Qing Xia, Sven Van Poucke, Ming-Hua Zheng

Journal: Medicine (Baltimore). 2016 Feb;95(8):e2928.

 

Scrub typhus is caused by Orientia tsutsugamushi. Any delay in diagnosis can result in delayed treatment and severe complications, including secondary hemophagocytic lymphohistiocytosis, which is rare but potentially fatal.In this paper, the authors present 3 cases of secondary hemophagocytic ...

Last Updated: 4 Mar 2016

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A Spatiotemporal Database to Track Human Scrub Typhus Using the VectorMap Application.
 

Author(s): Daryl J Kelly, Desmond H Foley, Allen L Richards

Journal:

 

Scrub typhus is a potentially fatal mite-borne febrile illness, primarily of the Asia-Pacific Rim. With an endemic area greater than 13 million km2 and millions of people at risk, scrub typhus remains an underreported, often misdiagnosed febrile illness. A comprehensive, updatable ...

Last Updated: 18 Dec 2015

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A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi).
 

Author(s): Andrew J Taylor, Daniel H Paris, Paul N Newton

Journal:

 

Scrub typhus, a bacterial infection caused by Orientia tsutsugamushi, is increasingly recognized as an important cause of fever in Asia, with an estimated one million infections occurring each year. Limited access to health care and the disease's non-specific symptoms mean that many ...

Last Updated: 15 Aug 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Scrub Typhus Antibiotic Resistance Trial
 

Status: Not yet recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 8 May 2017

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Scrub Typhus Pediatric Immunology Study
 

Status: Recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 31 Aug 2016

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Eschar Investigations in Scrub Typhus
 

Status: Not yet recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 22 Sep 2016

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