Tularemia

Common Name(s)

Tularemia

Tularemia is an infection common in wild rodents caused by the bacterium Francisella tularensis. It is transmitted to humans by contact with infected animal tissues or by ticks, biting flies, and mosquitoes. The condition is most common in North America and parts of Europe and Asia. It is very rare in the United States. The illness, which is characterized by fever, chills, headache, joint pain and muscle weakness, may continue for several weeks after symptoms begin. Streptomycin and tetracycline are commonly used to treat the infection.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tularemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tularemia" returned 130 free, full-text research articles on human participants. First 3 results:

Evaluation of patients with Tularemia in Bolu province in northwestern Anatolia, Turkey.
 

Author(s): Zafer Mengeloglu, Arif Duran, Ismail Necati Hakyemez, Tarik Ocak, Abdülkadir Kücükbayrak, Mustafa Karadag, Tekin Tas, Hayrettin Akdeniz

Journal:

 

Tularemia is a zoonotic disease caused by Francisella tularensis. Here we present an epidemic occurring in Bolu province, located in northwestern Anatolia in Turkey, and some features of the cases.

Last Updated: 12 Mar 2014

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[Investigation of the presence of Mycobacterium tuberculosis in the lymph node aspirates of the suspected tularemia lymphadenitis cases].
 

Author(s): Nurhan Albayrak, Bekir Celebi, Semra Kavas, Hülya Simşek, Selçuk Kılıç, Figen Sezen, Ahmet Arslantürk

Journal: Mikrobiyol Bul. 2014 Jan;48(1):129-34.

 

Recently reports of cervical tuberculous lymphadenitis and oropharyngeal tularemia which are the most common infectious causes of granulomatous lymphadenitis, have been significantly increased in Turkey. The differentiation of cervical tuberculous lymphadenitis and oropharyngeal tularemia ...

Last Updated: 10 Feb 2014

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Antibodies to both terminal and internal B-cell epitopes of Francisella tularensis O-polysaccharide produced by patients with tularemia.
 

Author(s): Zhaohua Lu, Hillary M Perkins, Jacqueline Sharon

Journal: Clin. Vaccine Immunol.. 2014 Feb;21(2):227-33.

 

Francisella tularensis, the Gram-negative bacterium that causes tularemia, is considered a potential bioterrorism threat due to its low infectivity dose and the high morbidity and mortality from respiratory disease. We previously characterized two mouse monoclonal antibodies (MAbs) ...

Last Updated: 30 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tularemia" returned 12 free, full-text review articles on human participants. First 3 results:

Neutrophils: potential therapeutic targets in tularemia?
 

Author(s): Lee-Ann H Allen

Journal:

 

The central role of neutrophils in innate immunity and host defense has long been recognized, and the ability of these cells to efficiently engulf and kill invading bacteria has been extensively studied, as has the role of neutrophil apoptosis in resolution of the inflammatory response. ...

Last Updated: 10 Jan 2014

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Immunotherapy for tularemia.
 

Author(s): Jerod A Skyberg

Journal: Virulence. 2013 Nov;4(8):859-70.

 

Francisella tularensis is a gram-negative bacterium that causes the zoonotic disease tularemia. Francisella is highly infectious via the respiratory route (~10 CFUs) and pulmonary infections due to type A strains of F. tularensis are highly lethal in untreated patients (> 30%). In ...

Last Updated: 31 Jan 2014

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Live attenuated tularemia vaccines: recent developments and future goals.
 

Author(s): Mark E Marohn, Eileen M Barry

Journal: Vaccine. 2013 Aug;31(35):3485-91.

 

In the aftermath of the 2001 anthrax attacks in the U.S., numerous efforts were made to increase the level of preparedness against a biological attack both in the US and worldwide. As a result, there has been an increase in research interest in the development of vaccines and other ...

Last Updated: 29 Jul 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
 

Status: Recruiting

Condition Summary: Infection; Hypertension; Anesthesia; Pain; Reflux; Nausea; Edema; Hyperlipidemia; Hypotension; Hypercholesterolemia; Sedation; Anxiolysis; Benzodiazepine Withdrawal; Bipolar Disorder; Autistic Disorder; Schizophrenia; Influenza Treatment or Prophylaxis; Acute Decompensated Heart Failure; Stable Angina; Life-threatening Fungal Infections; Nosocomial Pneumonia; Community Acquired Pneumonia; Acute Bacterial Exacerbation of Chronic Bronchitis; Complicated Skin and Skin Structure Infections; Uncomplicated Skin and Skin Structure Infections; Chronic Bacterial Prostatitis; Complicated Urinary Tract Infections; Acute Pyelonephritis; Uncomplicated Urinary Tract Infections; Inhalational Anthrax (Post-Exposure)

 

Last Updated: 30 Jul 2014

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