Tropical spastic paraparesis

Common Name(s)

Tropical spastic paraparesis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tropical spastic paraparesis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tropical spastic paraparesis" returned 102 free, full-text research articles on human participants. First 3 results:

Proprioceptive neuromuscular facilitation in HTLV-I-associated myelopathy/tropical spastic paraparesis.
 

Author(s): Vera Lúcia Santos de Britto, Rosalie Correa, Maurice Borges Vincent

Journal: Rev. Soc. Bras. Med. Trop.. ;47(1):24-9.

 

Human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) can impact the independence and motricity of patients. The aims of this study were to estimate the effects of physiotherapy on the functionality of patients with HAM/TSP during the ...

Last Updated: 7 Mar 2014

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CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis.
 

Author(s): Soraya Maria Menezes, Daniele Decanine, David Brassat, Ricardo Khouri, Saul V Schnitman, Ramon Kruschewsky, Giovanni López, Carolina Alvarez, Michael Talledo, Eduardo Gotuzzo, Anne-Mieke Vandamme, Bernardo Galvão-Castro, Roland Liblau, Johan Van Weyenbergh

Journal:

 

Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies with long-term clinical benefits or validated biomarkers ...

Last Updated: 11 Feb 2014

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CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis.
 

Author(s): Tomoo Sato, Ariella Coler-Reilly, Atae Utsunomiya, Natsumi Araya, Naoko Yagishita, Hitoshi Ando, Junji Yamauchi, Eisuke Inoue, Takahiko Ueno, Yasuhiro Hasegawa, Kusuki Nishioka, Toshihiro Nakajima, Steven Jacobson, Shuji Izumo, Yoshihisa Yamano

Journal:

 

Human T-lymphotropic virus type 1 (HTLV-1) -associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. Since the disease course of HAM/TSP varies among patients, there is a dire need for biomarkers capable of predicting the rate of disease ...

Last Updated: 16 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tropical spastic paraparesis" returned 7 free, full-text review articles on human participants. First 3 results:

Treatment of HTLV-I-associated myelopathy/tropical spastic paraparesis: toward rational targeted therapy.
 

Author(s): Unsong Oh, Steven Jacobson

Journal: Neurol Clin. 2008 Aug;26(3):781-97, ix-x.

 

The treatment of HAM/TSP is a challenge. No agent has shown to significantly modify the long-term disability associated with HAM/TSP. Advances in our understanding of the pathogenesis of HAM/TSP have led to the identification of several biomarkers and therapeutic targets. Clinical ...

Last Updated: 28 Jul 2008

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Possible etiologies for tropical spastic paraparesis and human T lymphotropic virus I-associated myelopathy.
 

Author(s): V Zaninovic'

Journal: Braz. J. Med. Biol. Res.. 2004 Jan;37(1):1-12.

 

The epidemiology of tropical spastic paraparesis/human T lymphotropic virus I (HTLV-I)-associated myelopathy (TSP/HAM) is frequently inconsistent and suggests environmental factors in the etiology of these syndromes. The neuropathology corresponds to a toxometabolic or autoimmune ...

Last Updated: 22 Dec 2003

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HTLV-I negative tropical spastic paraparesis: a scientific challenge.
 

Author(s): C M Castro-Costa, H Carton, T J Santos

Journal: Arq Neuropsiquiatr. 2001 Jun;59(2-A):289-94.

 

We reviewed the historical, clinical and etiological aspects of the progressive chronic spastic myelopathies of unknown etiology, disserting on the clinical similarities between HTLV-I seropositive and seronegative tropical spastic paraparesis (TSP), as well as focusing on the PCR ...

Last Updated: 11 Jun 2001

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Patients With HAM/TSP
 

Status: Recruiting

Condition Summary: HTLV-I Infection; Tropical Spastic Paraparesis

 

Last Updated: 19 Aug 2014

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Raltegravir for HAM/TSP
 

Status: Recruiting

Condition Summary: HAM/TSP; HTLV-1

 

Last Updated: 19 Mar 2014

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