Trigeminal neuralgia

Common Name(s)

Trigeminal neuralgia

Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of the face), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor.  In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.   

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

View Details
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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trigeminal neuralgia" returned 233 free, full-text research articles on human participants. First 3 results:

Rat Model of Trigeminal Neuralgia Using Cobra Venom Mimics the Electron Microscopy, Behavioral, and Anticonvulsant Drug Responses Seen in Patients.
 

Author(s): Qian-Qian Zhao, Xiao-Yan Qian, Jian-Xiong An, Cai-Cai Liu, Qi-Wu Fang, Yong Wang, Yi-De Jiang, Doris K Cope, John P Williams

Journal: Pain Physician. 2015 Nov;18(6):E1083-90.

 

A new animal model of trigeminal neuralgia produced by injecting cobra venom into the infraorbital nerve (ION) trunk in rats had been developed. We tested and extended the model by observing the ultrastructural alterations of neurons and ameliorative effect of pregabalin in cobra ...

Last Updated: 26 Nov 2015

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Predictive Factors Associated with Success and Failure for Radiofrequency Thermocoagulation in Patients with Trigeminal Neuralgia.
 

Author(s): Hyun Seung Jin, Ji Yeon Shin, Yong-Chul Kim, Sang Chul Lee, Eun Joo Choi, Pyung-Bok Lee, Jee Youn Moon

Journal: Pain Physician. 2015 Nov;18(6):537-45.

 

Radiofrequency thermocoagulation (RFT) has been widely used to manage trigeminal neuralgia (TN) refractory to oral medication. Careful selection of patients for managing TN with RFT can decrease morbidity and improve treatment efficacy.

Last Updated: 26 Nov 2015

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The Long-Term Effective Rate of Different Branches of Idiopathic Trigeminal Neuralgia After Single Radiofrequency Thermocoagulation: A Cohort Study.
 

Author(s): Yuan-Zhang Tang, Bai-Shan Wu, Li-Qiang Yang, Jian-Ning Yue, Liang-Liang He, Na Li, Jia-Xiang Ni

Journal: Medicine (Baltimore). 2015 Nov;94(45):e1994.

 

To evaluate the efficacy of computed tomography (CT) guided single radiofrequency thermocoagualtion (RFT) in 1137 patients with idiopathic trigeminal neuralgia after a follow-up period of 11 years, specially focused on duration of pain relief in different branches of trigeminal nerve, ...

Last Updated: 12 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trigeminal neuralgia" returned 31 free, full-text review articles on human participants. First 3 results:

Pharmaceutical Management of Trigeminal Neuralgia in the Elderly.
 

Author(s): M A E-M Oomens, T Forouzanfar

Journal: Drugs Aging. 2015 Sep;32(9):717-26.

 

Classical trigeminal neuralgia (CTN) is a severe neuropathic pain in the distribution of one or more branches of the trigeminal nerve, which occurs in recurrent episodes, causing deterioration in quality of life, affecting everyday habits and inducing severe disability. The aim of ...

Last Updated: 23 Sep 2015

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OnabotulinumtoxinA for trigeminal neuralgia: a review of the available data.
 

Author(s): Pedro A Kowacs, Marco A T Utiumi, Fábio A Nascimento, Elcio J Piovesan, Helio A G Teive

Journal: Arq Neuropsiquiatr. 2015 Oct;73(10):877-84.

 

Trigeminal neuralgia (TN) patients may develop side effects from centrally acting drugs, have contraindications for neurosurgical procedures, or experience relapse during conventional therapies. OnabotulinumtoxinA (BoNT/A) has been reported to be effective for TN, although this finding ...

Last Updated: 15 Oct 2015

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[Treatment of trigeminal neuralgia: an update and future prospects of percutaneous techniques].
 

Author(s): Agustín Bescós, Vicenç Pascual, Marcos Escosa-Bage, Xavier Malaga

Journal: Rev Neurol. 2015 Aug;61(3):114-24.

 

Trigeminal neuralgia is one of the most severe facial pain syndromes. The annual incidence varies between 4-13% and has a significant effect on patients' quality of life. When the pain cannot be controlled by pharmacological treatment, several different surgical options can be considered. ...

Last Updated: 16 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 8 Aug 2016

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RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 9 Mar 2016

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Last Updated: 1 Jun 2011

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