Trigeminal neuralgia

Common Name(s)

Trigeminal neuralgia

Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of the face), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor.  In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.   

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

View Details
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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trigeminal neuralgia" returned 241 free, full-text research articles on human participants. First 3 results:

Trigeminal somatosensory-evoked potential: A neurophysiological tool to monitor the extent of lesion of ganglion radiofrequency thermocoagulation in idiopathic trigeminal neuralgia: A case-control study.
 

Author(s): Yan-Xing Zhao, Su-Hua Miao, Yuan-Zhang Tang, Liang-Liang He, Li-Qiang Yang, Yu Ma, Jia-Xiang Ni

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5872.

 

To reflect the extent of thermolesion of ganglion by testing the change of trigeminal somatosensory-evoked potential (TSEP) before and after ganglion radiofrequency thermocoagulation surgery (GRT), and evaluate long-term clinic effect by follow-up visiting of 1 year.Patients with ...

Last Updated: 18 Jan 2017

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Atypical Trigeminal Neuralgia: A Rare Neurological Manifestation of Systemic Lupus Erythematosus.
 

Author(s): Viki Kumar, Jaspinder Kaur, Pallavi Pothuri, Sahiba Bandagi

Journal:

 

BACKGROUND Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder of unknown etiology which can present at any age with symptoms of mucocutaneous, musculoskeletal, renal, central nervous system, and nonspecific clinical pictures making the disease a "master of mimicry". ...

Last Updated: 12 Jan 2017

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Percutaneous trigeminal ganglion radiofrequency thermocoagulation alleviates anxiety and depression disorders in patients with classic trigeminal neuralgia: A cohort study.
 

Author(s): YuanZhang Tang, Ling Ma, Na Li, Yuna Guo, Liqiang Yang, Baishan Wu, Jianning Yue, Qi Wang, Jingjie Liu, Jia-Xiang Ni

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5379.

 

Trigeminal neuralgia (TN) is a neurological condition that presents as excruciating facial pain. Depression and anxiety are commonly associated with TN; however, anxiety and depression disorders in patients with TN and the effects of the various therapeutic strategies for TN on these ...

Last Updated: 8 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trigeminal neuralgia" returned 32 free, full-text review articles on human participants. First 3 results:

Therapeutic efficacy and safety of Botulinum Toxin A Therapy in Trigeminal Neuralgia: a systematic review and meta-analysis of randomized controlled trials.
 

Author(s): Mostafa Ebraheem Morra, Ahmed Elgebaly, Ahmed Elmaraezy, Adham M Khalil, Ahmed M A Altibi, Tran Le-Huy Vu, Mostafa Reda Mostafa, Nguyen Tien Huy, Kenji Hirayama

Journal: J Headache Pain. 2016 Dec;17(1):63.

 

Several different interventions have been examined to alleviate pain and reduce frequency of trigeminal neuralgia (TN) paroxysms. However, some patients continue to have persistent or recurrent painful attacks. Using a systematic review and meta-analysis approach, we aimed to synthesize ...

Last Updated: 8 Jul 2016

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Trigeminal Neuralgia as an Unusual Isolated Symptom of Pituitary Adenoma: Case Report and Review of the Literature.
 

Author(s): Oktay Gurcan, Ahmet Gurhan Gurcay, Atilla Kazanci, Ali Erdem Yildirim, Omer Faruk Turkoglu, Hatice Ferhan Komurcu, Ethem Beskonakli

Journal: Turk Neurosurg. 2016 ;26(1):180-3.

 

Pituitary adenomas account for approximately 10% of intracranial tumors and 5% are locally invasive. Cavernous sinus invasion by pituitary tumors presents mostly with cranial nerve palsies, especially involving the third, fourth and sixth cranial nerves, which is well documented in ...

Last Updated: 15 Jan 2016

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Pharmaceutical Management of Trigeminal Neuralgia in the Elderly.
 

Author(s): M A E-M Oomens, T Forouzanfar

Journal: Drugs Aging. 2015 Sep;32(9):717-26.

 

Classical trigeminal neuralgia (CTN) is a severe neuropathic pain in the distribution of one or more branches of the trigeminal nerve, which occurs in recurrent episodes, causing deterioration in quality of life, affecting everyday habits and inducing severe disability. The aim of ...

Last Updated: 23 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 5 Dec 2016

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RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 12 Sep 2016

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Botulinum Toxin for the Treatment of Trigeminal Neuralgia
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 13 Jun 2016

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