Trigeminal neuralgia

Common Name(s)

Trigeminal neuralgia

Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of the face), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor.  In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.   

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trigeminal neuralgia" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

View Details
Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trigeminal neuralgia" returned 234 free, full-text research articles on human participants. First 3 results:

Botulinum neurotoxin type A in the treatment of classical Trigeminal Neuralgia (BoTN): study protocol for a randomized controlled trial.
 

Author(s): Jan Burmeister, Dagny Holle, Eva Bock, Claudia Ose, Hans-Christoph Diener, Mark Obermann

Journal:

 

Trigeminal neuralgia is characterized by paroxysmal facial pain attacks. Adequate prophylactic drug therapy is often limited by the lack of efficacy and intolerance due to central nervous system side effects. Subcutaneous injections of botulinum toxin type A are a promising treatment ...

Last Updated: 4 Dec 2015

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Rat Model of Trigeminal Neuralgia Using Cobra Venom Mimics the Electron Microscopy, Behavioral, and Anticonvulsant Drug Responses Seen in Patients.
 

Author(s): Qian-Qian Zhao, Xiao-Yan Qian, Jian-Xiong An, Cai-Cai Liu, Qi-Wu Fang, Yong Wang, Yi-De Jiang, Doris K Cope, John P Williams

Journal: Pain Physician. 2015 Nov;18(6):E1083-90.

 

A new animal model of trigeminal neuralgia produced by injecting cobra venom into the infraorbital nerve (ION) trunk in rats had been developed. We tested and extended the model by observing the ultrastructural alterations of neurons and ameliorative effect of pregabalin in cobra ...

Last Updated: 26 Nov 2015

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Predictive Factors Associated with Success and Failure for Radiofrequency Thermocoagulation in Patients with Trigeminal Neuralgia.
 

Author(s): Hyun Seung Jin, Ji Yeon Shin, Yong-Chul Kim, Sang Chul Lee, Eun Joo Choi, Pyung-Bok Lee, Jee Youn Moon

Journal: Pain Physician. 2015 Nov;18(6):537-45.

 

Radiofrequency thermocoagulation (RFT) has been widely used to manage trigeminal neuralgia (TN) refractory to oral medication. Careful selection of patients for managing TN with RFT can decrease morbidity and improve treatment efficacy.

Last Updated: 26 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trigeminal neuralgia" returned 32 free, full-text review articles on human participants. First 3 results:

Trigeminal Neuralgia as an Unusual Isolated Symptom of Pituitary Adenoma: Case Report and Review of the Literature.
 

Author(s): Oktay Gurcan, Ahmet Gurhan Gurcay, Atilla Kazanci, Ali Erdem Yildirim, Omer Faruk Turkoglu, Hatice Ferhan Komurcu, Ethem Beskonakli

Journal: Turk Neurosurg. 2016 ;26(1):180-3.

 

Pituitary adenomas account for approximately 10% of intracranial tumors and 5% are locally invasive. Cavernous sinus invasion by pituitary tumors presents mostly with cranial nerve palsies, especially involving the third, fourth and sixth cranial nerves, which is well documented in ...

Last Updated: 15 Jan 2016

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Pharmaceutical Management of Trigeminal Neuralgia in the Elderly.
 

Author(s): M A E-M Oomens, T Forouzanfar

Journal: Drugs Aging. 2015 Sep;32(9):717-26.

 

Classical trigeminal neuralgia (CTN) is a severe neuropathic pain in the distribution of one or more branches of the trigeminal nerve, which occurs in recurrent episodes, causing deterioration in quality of life, affecting everyday habits and inducing severe disability. The aim of ...

Last Updated: 23 Sep 2015

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OnabotulinumtoxinA for trigeminal neuralgia: a review of the available data.
 

Author(s): Pedro A Kowacs, Marco A T Utiumi, Fábio A Nascimento, Elcio J Piovesan, Helio A G Teive

Journal: Arq Neuropsiquiatr. 2015 Oct;73(10):877-84.

 

Trigeminal neuralgia (TN) patients may develop side effects from centrally acting drugs, have contraindications for neurosurgical procedures, or experience relapse during conventional therapies. OnabotulinumtoxinA (BoNT/A) has been reported to be effective for TN, although this finding ...

Last Updated: 15 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 2 Sep 2016

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RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery
 

Status: Recruiting

Condition Summary: Trigeminal Neuralgia

 

Last Updated: 12 Sep 2016

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Last Updated: 1 Jun 2011

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