Transverse myelitis

Common Name(s)

Transverse myelitis

Transverse myelitis is a neurological disorder caused by inflammation across both sides of one level, or segment, of the spinal cord. The term myelitis refers to inflammation of the spinal cord; transverse describes the position of the inflammation, that is, across the width of the spinal cord. Attacks of inflammation can damage or destroy myelin, the fatty insulating substance that covers nerve cell fibers. This damage causes nervous system scars that interrupt communications between the nerves in the spinal cord and the rest of the body. Transverse myelitis is part of a spectrum of neuroimmunologic diseases of the central nervous system. Other disorders in this spectrum include, Acute Disseminated Encephalomyelitis (ADEM), Optic Neuritis, and Neuromyelitis Optica (Devic's disease).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transverse myelitis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transverse myelitis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transverse myelitis" returned 111 free, full-text research articles on human participants. First 3 results:

Transverse myelitis and acute HIV infection: a case report.
 

Author(s): Paulo Andrade, Cristóvão Figueiredo, Cláudia Carvalho, Lurdes Santos, António Sarmento

Journal:

 

Most HIV infected patients will develop some sort of neurologic involvement of the disease throughout their lives, usually in advanced stages. Neurologic symptoms may occur in acute HIV infection but myelopathy in this setting is rare. Up until this date, only two cases of transverse ...

Last Updated: 24 Mar 2014

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Acute transverse myelitis: a rare neurological complication following wasp sting.
 

Author(s): Kolar Vishwanath Vinod, Madasamy Ponraj, Khened Swetharani, Tarun Kumar Dutta

Journal: Neurol India. ;62(1):88-9.

 

Last Updated: 10 Mar 2014

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Acute transverse myelitis during treatment with etanercept for severe plaque psoriasis.
 

Author(s): Juan Escalas, Nicole Knöpfel, Ana Martin-Santiago, Carmen Calles

Journal: J. Am. Acad. Dermatol.. 2014 Jan;70(1):e17-8.

 

Last Updated: 20 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transverse myelitis" returned 6 free, full-text review articles on human participants. First 3 results:

Transverse myelitis--a review of the presentation, diagnosis, and initial management.
 

Author(s): Timothy W West

Journal: Discov Med. 2013 Oct;16(88):167-77.

 

Myelitis is a rare neurological disorder of the spinal cord that is caused by inflammation and can have devastating neurologic effects with up to two-thirds of patients having a moderate to severe degree of residual disability. Symptoms typically develop over hours or days and then ...

Last Updated: 8 Oct 2013

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[Acute transverse myelitis: a clinical review and algorithm for diagnostic intervention].
 

Author(s): J M Gómez-Argüelles, A Sánchez-Solla, E López-Dolado, E Díez-De la Lastra, J Florensa

Journal: Rev Neurol. ;49(10):533-40.

 

Under the term of acute transverse myelitis (ATM), there are included a heterogeneous group of diseases, with the nexus common to produce an inflammatory focal injury of the spinal cord, of acute form. In order to try to group all the etiologies that can provoke this affectation, ...

Last Updated: 27 Oct 2009

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Transverse myelitis spectrum disorders.
 

Author(s): Lekha Pandit

Journal: Neurol India. ;57(2):126-33.

 

Acute transverse myelitis (ATM) is an inflammatory demyelinating disorder that affects the spinal cord focally resulting in motor sensory and autonomic dysfunction. Establishing the diagnosis of ATM is not as difficult as determining the possible etiology. There is a difference in ...

Last Updated: 14 May 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch)
 

Status: Recruiting

Condition Summary: Transverse Myelitis; Neuromyelitis Optica; Idiopathic Transverse Myelitis; Myelitis NOS

 

Last Updated: 16 Jun 2014

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PCORI Transverse Myelitis CAPTURE
 

Status: Recruiting

Condition Summary: Pediatric Transverse Myelitis; Onset of Symptoms Within 3 Months of Enrollment

 

Last Updated: 13 Jun 2014

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A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorder; Transverse Myelitis; Optic Neuritis

 

Last Updated: 5 Sep 2013

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