Transplantation

Common Name(s)

Transplantation

Transplantation is the process of moving an object from one place to another. Organ transplantation refers to the surgical transferring of a donor organ into a person in need, the recipient. Organ transplantation is often used to replace a damaged, dysfunctional, or missing organ usually due to illness or injury. End-stage organ failure is the most common reason for organ transplantation and some conditions that may lead to such a procedure include: cardiomyopathy (heart), cirrhosis of the liver, chronic obstructive pulmonary disease (lungs), diabetes, and cystic fibrosis among many others.

Donor transplant organs may come from living or deceased individuals and must be carefully matched to their recipient to reduce the chance of rejection. Transplant rejection occurs when a person's body reacts to the new organ tissue as if it were a foreign invader such as an infectious bacteria or virus. Using tissue from a close relative or someone closely matching the individual in need may lessen the chance of transplant rejection. Certain medications may also help repress the immune system while the body adjusts to the new organ or tissue.

Organs that have been successfully transplanted many times include the kidneys, liver, heart, lungs, pancreas, intestine, and thymus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves, and veins have also been successfully transplanted. Other organs and tissues have been transplanted, but are less common and often less successful. Your doctor or specialist can help guide you through the process should you or a loved one be in need of an organ transplant. Support groups are also a great resource for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transplantation" returned 21656 free, full-text research articles on human participants. First 3 results:

Physical Activity and Exercise as a Basic Preventive Measure (Primary Prevention, Prevention after Renal Transplantation).
 

Author(s): Věra Adámková, Jiří Bělohoubek, Václav Adámek, Martina Juhaňáková, Jan Pirk

Journal: Cent. Eur. J. Public Health. 2015 Nov;23 Suppl():S3-8.

 

Movement is an inseparable part of one's life, and has been a basic everyday activity through the history of mankind. However, a lack of physical activity and availability of food have resulted in a variety of serious health impairments. The 20th century has witnessed a steep rise ...

Last Updated: 6 Feb 2016

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Belatacept and Long-Term Outcomes in Kidney Transplantation.
 

Author(s): Flavio Vincenti, Lionel Rostaing, Joseph Grinyo, Kim Rice, Steven Steinberg, Luis Gaite, Marie-Christine Moal, Guillermo A Mondragon-Ramirez, Jatin Kothari, Martin S Polinsky, Herwig-Ulf Meier-Kriesche, Stephane Munier, Christian P Larsen

Journal: N. Engl. J. Med.. 2016 Jan;374(4):333-43.

 

In previous analyses of BENEFIT, a phase 3 study, belatacept-based immunosuppression, as compared with cyclosporine-based immunosuppression, was associated with similar patient and graft survival and significantly improved renal function in kidney-transplant recipients. Here we present ...

Last Updated: 28 Jan 2016

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Renal transplantation erythrocytosis among recipients of kidney transplantation of Afro-Arab origin patients.
 

Author(s): Elsharif Mohamed Elhafiz, Shawgi Abu Obeida Ahmed Abu Alga, Abd Allah Abd Elkareem Gibreel

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):172-3.

 

Last Updated: 20 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transplantation" returned 3142 free, full-text review articles on human participants. First 3 results:

Ethical and legal issues in renal transplantation in Nigeria.
 

Author(s): S O Ajayi, Y Raji, B L Salako

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):125-8.

 

With the increasing number of patients being offered kidney transplantation by many centers in the developing world, it is not unexpected that there would be attendant ethical and legal issues even when the selection process for transplantation seems medically justified. Because of ...

Last Updated: 20 Jan 2016

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Effect of pediatric liver transplantation on renal function.
 

Author(s): Hasan M A Isa, Afaf M Mohamed, Amer E Alderazi

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):1-8.

 

The aim of this review is to define the incidence of renal dysfunction among pediatric liver transplant (LT) survivors, to identify the associated risk factors and to outline the therapeutic options. Renal dysfunction is a common problem after pediatric LT. The measured glomerular ...

Last Updated: 20 Jan 2016

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Peri-operative immunonutrition in patients undergoing liver transplantation: a meta-analysis of randomized controlled trials.
 

Author(s): Qiucheng Lei, Xinying Wang, Huazhen Zheng, Jingcheng Bi, Shanjun Tan, Ning Li

Journal: Asia Pac J Clin Nutr. 2015 ;24(4):583-90.

 

No consensus has been reached concerning the effects of peri-operative immunonutrition in patients undergoing liver transplantation. We conducted a meta-analysis to evaluate the effects of peri-operative immunonutrition on clinical outcomes and liver function in patients undergoing ...

Last Updated: 23 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Collection and Storage of Umbilical Cord Blood for Transplantation
 

Status: Recruiting

Condition Summary: Cord Blood Stem Cell Transplantation; Cord Blood Transplantation; Hematopoietic Stem Cell Transplantation

 

Last Updated: 15 Feb 2016

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Hyperbaric Oxygen Therapy for Lung Transplantation
 

Status: Recruiting

Condition Summary: Disorder Related to Lung Transplantation; Central Airway Stenosis; Airway Exudative Plaques; Airway Complications Post-Lung Transplantation

 

Last Updated: 20 Jan 2016

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CEUS in Kidney and Pancreas Transplantation
 

Status: Recruiting

Condition Summary: Kidney Transplantation; Pancreas Transplantation

 

Last Updated: 3 Apr 2014

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