Transplantation

Common Name(s)

Transplantation

Transplantation is the process of moving an object from one place to another. Organ transplantation refers to the surgical transferring of a donor organ into a person in need, the recipient. Organ transplantation is often used to replace a damaged, dysfunctional, or missing organ usually due to illness or injury. End-stage organ failure is the most common reason for organ transplantation and some conditions that may lead to such a procedure include: cardiomyopathy (heart), cirrhosis of the liver, chronic obstructive pulmonary disease (lungs), diabetes, and cystic fibrosis among many others.

Donor transplant organs may come from living or deceased individuals and must be carefully matched to their recipient to reduce the chance of rejection. Transplant rejection occurs when a person's body reacts to the new organ tissue as if it were a foreign invader such as an infectious bacteria or virus. Using tissue from a close relative or someone closely matching the individual in need may lessen the chance of transplant rejection. Certain medications may also help repress the immune system while the body adjusts to the new organ or tissue.

Organs that have been successfully transplanted many times include the kidneys, liver, heart, lungs, pancreas, intestine, and thymus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves, and veins have also been successfully transplanted. Other organs and tissues have been transplanted, but are less common and often less successful. Your doctor or specialist can help guide you through the process should you or a loved one be in need of an organ transplant. Support groups are also a great resource for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transplantation" returned 19965 free, full-text research articles on human participants. First 3 results:

[Value of C-reactive protein level on transplantation day in predicting early post-transplant infections and outcomes of allogeneic hematopoietic stem cell transplantation].
 

Author(s): Kefeng Shen, Qifa Liu, Jing Sun, Qianli Jiang, Yu Zhang, Hongsheng Zhou, Min Dai, Min Xiao, Jin Wang, Li Luo, Qinlu Li, Haiyun An, Zhen-Ya Hong, Li Meng, Mo Yang, Jianfeng Zhou, Gaoxiang Wang

Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Nov;35(11):1535-9.

 

To investigate the value of C-reactive protein (CRP) on transplantation day in predicting early post-transplant infections and outcomes of allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Last Updated: 26 Nov 2015

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Anaphylaxis on Graft Reperfusion during Orthotopic Liver Transplantation: A Case Study.
 

Author(s): Nada Andjelić, Svetlana Erdeljan, Radmila Popović, Teodora Božić

Journal: Srp Arh Celok Lek. ;143(7-8):467-70.

 

Hemodynamic instability is a common occurrence during liver transplantation (LT). Hypotension and hemodynamic instability during graft reperfusion are most commonly consequences of the postreperfusion syndrome (PRS).

Last Updated: 28 Oct 2015

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Design and Implementation of the International Genetics and Translational Research in Transplantation Network.
 

Author(s):

Journal: Transplantation. 2015 Nov;99(11):2401-12.

 

Genetic association studies of transplantation outcomes have been hampered by small samples and highly complex multifactorial phenotypes, hindering investigations of the genetic architecture of a range of comorbidities which significantly impact graft and recipient life expectancy. ...

Last Updated: 23 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transplantation" returned 2936 free, full-text review articles on human participants. First 3 results:

Fecal Microbiota Transplantation for Clostridium difficile-Associated Diarrhea.
 

Author(s): Nathaniel A Cohen, Ronen Ben Ami, Hanan Guzner-Gur, Moshe E Santo, Zamir Halpern, Nitsan Maharshak

Journal: Isr. Med. Assoc. J.. 2015 Aug;17(8):510-4.

 

Clostridium difficile-associated diarrhea is a problem most hospital-based physicians will face in their career. This review aims to refresh current knowledge with regard to Clostridium difficile infection and bring physicians up to date with the latest developments in the growing ...

Last Updated: 23 Sep 2015

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Novel H1N1 influenza infection among post-renal transplantation subjects: A mini review.
 

Author(s): Beuy Joob, Viroj Wiwanitkit

Journal: Saudi J Kidney Dis Transpl. 2015 Sep;26(5):1006-8.

 

Last Updated: 10 Sep 2015

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Heart transplantation: review.
 

Author(s): Sandrigo Mangini, Bárbara Rubim Alves, Odílson Marcos Silvestre, Philippe Vieira Pires, Lucas José Tachotti Pires, Milena Novaes Cardoso Curiati, Fernando Bacal

Journal: Einstein (Sao Paulo). ;13(2):310-8.

 

Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices ...

Last Updated: 9 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Collection and Storage of Umbilical Cord Blood for Transplantation
 

Status: Recruiting

Condition Summary: Cord Blood Stem Cell Transplantation; Cord Blood Transplantation; Hematopoietic Stem Cell Transplantation

 

Last Updated: 13 Aug 2015

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Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation
 

Status: Recruiting

Condition Summary: Heart Transplantation; Liver Transplantation; Kidney Transplantation

 

Last Updated: 29 Sep 2015

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Hyperbaric Oxygen Therapy for Lung Transplantation
 

Status: Recruiting

Condition Summary: Disorder Related to Lung Transplantation; Central Airway Stenosis; Airway Exudative Plaques; Airway Complications Post-Lung Transplantation

 

Last Updated: 20 Jan 2016

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