Transplantation

Common Name(s)

Transplantation

Transplantation is the process of moving an object from one place to another. Organ transplantation refers to the surgical transferring of a donor organ into a person in need, the recipient. Organ transplantation is often used to replace a damaged, dysfunctional, or missing organ usually due to illness or injury. End-stage organ failure is the most common reason for organ transplantation and some conditions that may lead to such a procedure include: cardiomyopathy (heart), cirrhosis of the liver, chronic obstructive pulmonary disease (lungs), diabetes, and cystic fibrosis among many others.

Donor transplant organs may come from living or deceased individuals and must be carefully matched to their recipient to reduce the chance of rejection. Transplant rejection occurs when a person's body reacts to the new organ tissue as if it were a foreign invader such as an infectious bacteria or virus. Using tissue from a close relative or someone closely matching the individual in need may lessen the chance of transplant rejection. Certain medications may also help repress the immune system while the body adjusts to the new organ or tissue.

Organs that have been successfully transplanted many times include the kidneys, liver, heart, lungs, pancreas, intestine, and thymus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves, and veins have also been successfully transplanted. Other organs and tissues have been transplanted, but are less common and often less successful. Your doctor or specialist can help guide you through the process should you or a loved one be in need of an organ transplant. Support groups are also a great resource for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transplantation" returned 22885 free, full-text research articles on human participants. First 3 results:

Everolimus for pediatric patients with acute graft-versus-host disease after hematopoietic stem cell transplantation: A pilot study.
 

Author(s): Yu-Hua Chao, Yin-Chen Chang, Han-Ping Wu, Ching-Tien Peng, Te-Fu Weng, Kang-Hsi Wu

Journal: Medicine (Baltimore). 2017 Nov;96(44):e8464.

 

Acute graft-versus-host disease (aGVHD) is a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Due to the poor prognosis for patients not responding to first-line steroids treatment, improvements in aGVHD therapy are needed. ...

Last Updated: 2 Nov 2017

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Duplicate publication bias weakens the validity of meta-analysis of immunosuppression after transplantation.
 

Author(s): Cameron J Fairfield, Ewen M Harrison, Stephen J Wigmore

Journal: World J. Gastroenterol.. 2017 Oct;23(39):7198-7200.

 

Duplicate publication can introduce significant bias into a meta-analysis if studies are inadvertently included more than once. Many studies are published in more than one journal to maximize readership and impact of the study findings. Inclusion of multiple publications of the same ...

Last Updated: 2 Nov 2017

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Thrombosis after liver transplantation for hepatocellular carcinoma.
 

Author(s): Ida Martinelli, Francesca R Ponziani, Alberto Maino, Sherrie Bhoori, Maria Abbattista, Umberto Maggi, Tullia M De Feo, Paolo Bucciarelli, Andrea Artoni, Elena Longhi, Marta Serafini, Giorgio Rossi, Vincenzo Mazzaferro

Journal:

 

The influence of thrombosis on the prognosis of patients with hepatocellular carcinoma (HCC) after liver transplantation (LT) and the role of the commonest inherited thrombophilia abnormalities factor V Leiden and prothrombin G20210A in the development of thrombosis are unknown. We ...

Last Updated: 26 Oct 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transplantation" returned 3358 free, full-text review articles on human participants. First 3 results:

Alemtuzumab versus antithymocyte globulin induction therapies in kidney transplantation patients: A systematic review and meta-analysis of randomized controlled trials.
 

Author(s): Jianming Zheng, Wenli Song

Journal: Medicine (Baltimore). 2017 Jul;96(28):e7151.

 

Alemtuzumab (ALEM) is widely used as an induction therapy for organ transplantation, and numerous randomized controlled trials (RCTs) have been published to evaluate its efficacy and safety in kidney transplantation as compared with antithymocyte globulin (ATG). The purpose of this ...

Last Updated: 12 Jul 2017

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Living Donor Liver Transplantation.
 

Author(s): Birkan Bozkurt, Murat Dayangac, Yaman Tokat

Journal: Chirurgia (Bucur). ;112(3):217-228.

 

In 50 years after the first liver transplantation, the medical world has witnessed the liver transplantation to become one of the widely recognized and leading branches of surgery. In this period, liver transplantation combined with surgical technique, patient selection, advancements ...

Last Updated: 4 Jul 2017

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Graft-versus-host-disease after kidney transplantation: A case report and literature review.
 

Author(s): Yanhua Guo, Shouyang Ding, Hui Guo, Shenqiu Li, Xia Lu, Zhishui Chen, Zhonghua Klaus Chen, Changsheng Ming, Nianqiao Gong

Journal: Medicine (Baltimore). 2017 Jun;96(26):e7333.

 

Acute graft-versus-host-disease (GVHD) in kidney recipients is extremely rare. Knowledge about its clinical manifestations, diagnosis, treatment, and prognosis is limited and needs to be increased.

Last Updated: 28 Jun 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study
 

Status: Recruiting

Condition Summary: Transplantation

 

Last Updated: 8 Aug 2017

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Postconditioning by Cyclosporin A in Pulmonary Transplantation
 

Status: Not yet recruiting

Condition Summary: Lung Transplantation

 

Last Updated: 29 Aug 2016

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Last Updated: 8 Mar 2016

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