Transplantation

Common Name(s)

Transplantation

Transplantation is the process of moving an object from one place to another. Organ transplantation refers to the surgical transferring of a donor organ into a person in need, the recipient. Organ transplantation is often used to replace a damaged, dysfunctional, or missing organ usually due to illness or injury. End-stage organ failure is the most common reason for organ transplantation and some conditions that may lead to such a procedure include: cardiomyopathy (heart), cirrhosis of the liver, chronic obstructive pulmonary disease (lungs), diabetes, and cystic fibrosis among many others.

Donor transplant organs may come from living or deceased individuals and must be carefully matched to their recipient to reduce the chance of rejection. Transplant rejection occurs when a person's body reacts to the new organ tissue as if it were a foreign invader such as an infectious bacteria or virus. Using tissue from a close relative or someone closely matching the individual in need may lessen the chance of transplant rejection. Certain medications may also help repress the immune system while the body adjusts to the new organ or tissue.

Organs that have been successfully transplanted many times include the kidneys, liver, heart, lungs, pancreas, intestine, and thymus. Tissues such as bones, tendons, cornea, skin, heart valves, nerves, and veins have also been successfully transplanted. Other organs and tissues have been transplanted, but are less common and often less successful. Your doctor or specialist can help guide you through the process should you or a loved one be in need of an organ transplant. Support groups are also a great resource for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transplantation" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transplantation" returned 24215 free, full-text research articles on human participants. First 3 results:

Using an informatics education strategy to resolve the dilemma of teaching transplantation in medical institutions: Multidisciplinary medical team perspectives.
 

Author(s): Ming H Hsieh, Fu-Jong Shih, Shuh-Jen Sheu, Shoei-Shen Wang, Fu-Jin Shih

Journal: Medicine (Baltimore). 2018 Oct;97(43):e12809.

 

In Taiwan, the current survival rate 1 year after transplantation exceeds 80%. However, the number of organ/tissue donors per year in Taiwan is extremely low, resulting in increased mortality. This is also true in Europe and in the United States. Recently, data from the Taiwan Organ ...

Last Updated: 31 Dec 1969

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Successful second allogeneic stem-cell transplantation from the same sibling donor for a patient with recurrent hepatosplenic gamma-delta (γ/δ) T-cell lymphoma: A case report.
 

Author(s): Hui Pan, Jing Huang, Jun-Nan Li, Li Yang, Jian-Yu Wang, Xin Wang, Lin Liu, Ze-Song Yang, Li Wang

Journal: Medicine (Baltimore). 2018 Nov;97(44):e12941.

 

Hepatosplenic T-cell lymphoma (HSTCL) is a rare but aggressive type of peripheral T-cell lymphoma (PTCL). There is an urgent need for effective treatment due to the poor prognosis of HSTCL. Here, for the 1st time we describe the rare successful case of HSTCL who relapsed after a previous ...

Last Updated: 31 Dec 1969

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Transplantation, gene therapy and intestinal pathology in MNGIE patients and mice.
 

Author(s): Rana Yadak, Max V Boot, Niek P van Til, Dominique Cazals-Hatem, Armin Finkenstedt, Elly Bogaerts, Irenaeus F de Coo, Marianna Bugiani

Journal:

 

Gastrointestinal complications are the main cause of death in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Available treatments often restore biochemical homeostasis, but fail to cure gastrointestinal symptoms.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transplantation" returned 3678 free, full-text review articles on human participants. First 3 results:

Immediate versus conventional postoperative tracheal extubation for enhanced recovery after liver transplantation: IPTE versus CTE for enhanced recovery after liver transplantation.
 

Author(s): Jianbo Li, Chengdi Wang, Yuting Jiang, Jiulin Song, Longhao Zhang, Nan Chen, Rui Zhang, Lan Yang, Qin Yao, Li Jiang, Jian Yang, Tao Zhu, Yang Yang, Weimin Li, Lunan Yan, Jiayin Yang

Journal: Medicine (Baltimore). 2018 Nov;97(45):e13082.

 

To systematically compare immediate postoperative tracheal extubation (IPTE) with conventional tracheal extubation (CTE) and to determine whether IPTE can achieve an enhanced recovery for adult patients underwent liver transplantation (LT) without additional risks. We designed a systematic ...

Last Updated: 31 Dec 1969

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Short-term and long-term outcomes of liver transplantation using moderately and severely steatotic donor livers: A systematic review.
 

Author(s): Chenjiao Wu, Chao Lu, Chengfu Xu

Journal: Medicine (Baltimore). 2018 Aug;97(35):e12026.

 

The aim of this study was to perform a systemic review of the studies addressing the use of moderately and severely steatotic donor livers for liver transplantation.

Last Updated: 31 Dec 1969

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Ubiquitin-proteasome system and oxidative stress in liver transplantation.
 

Author(s): Norma Alva, Arnau Panisello-Roselló, Marta Flores, Joan Roselló-Catafau, Teresa Carbonell

Journal: World J. Gastroenterol.. 2018 Aug;24(31):3521-3530.

 

A major issue in organ transplantation is the development of a protocol that can preserve organs under optimal conditions. Damage to organs is commonly a consequence of flow deprivation and oxygen starvation following the restoration of blood flow and reoxygenation. This is known ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Thromboelastometry as a Predictor of Thrombotic Complications During Pediatric Recipient Liver Transplantation
 

Status: Recruiting

Condition Summary: Pediatric Liver Transplantation

 

Last Updated: 4 Apr 2018

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Enteric Microbiome and Liver Transplantation
 

Status: Recruiting

Condition Summary: Orthotopic Liver Transplantation

 

Last Updated: 10 Sep 2018

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Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study
 

Status: Recruiting

Condition Summary: Transplantation

 

Last Updated: 8 Aug 2017

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