Bannayan-Riley-Ruvalcaba Syndrome

Common Name(s)

Bannayan-Riley-Ruvalcaba Syndrome

Bannayan-Riley-Ruvalcaba syndrome (BRRS) is one of the PTEN hamartoma tumor syndromes (PHTS), a spectrum of disorders caused by mutations in a gene called PTEN. BRRS is a disorder present from birth that is characterized by macrocephaly (larger than normal sized head), intestinal polyposis (multiple benign polyps in the intestines), lipomas (tumors below the skin made up of fatty tissue), and pigmented skin lesion (macule) in the area of the penis called the glans penis. The symptoms of BRRS vary from person to person. Treatment is based on the symptoms present; however, because of the increased risk of developing cancer in people with the PHTS, increased cancer surveillance is recommended.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bannayan-Riley-Ruvalcaba Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bannayan-Riley-Ruvalcaba Syndrome" returned 14 free, full-text research articles on human participants. First 3 results:

Bannayan-Riley-Ruvalcaba syndrome with deforming lipomatous hamartomas in infant--case report.
 

Author(s): Gabriela Maria Abreu Gontijo, Clóvis Antonio Lopes Pinto, Silvia Regina Rogatto, Isabela Werneck da Cunha, Samuel Aguiar, Célia Antônia Xavier de Moraes Alves

Journal: An Bras Dermatol. ;88(6):982-5.

 

Bannayan-Riley-Ruvalcaba Syndrome is a rare condition caused by mutations in the PTEN gene. It displays association of multiple lipomas, macrocephaly, hemangiomas, hamartomatous intestinal polyposis, developmental delay and speckled pigmented maculae on the male genitalia. We report ...

Last Updated: 29 Jan 2014

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Thyroid involvement in two patients with Bannayan-Riley-Ruvalcaba syndrome.
 

Author(s): Valentina Peiretti, Alessandro Mussa, Francesca Feyles, Gerdi Tuli, Arianna Santanera, Cristina Molinatto, Giovanni Battista Ferrero, Andrea Corrias

Journal: J Clin Res Pediatr Endocrinol. 2013 ;5(4):261-5.

 

Bannayan-Riley-Ruvalcaba syndrome (BRRs) is an overgrowth disorder characterized by macrocephaly, pigmented maculae of the glans penis, and benign mesodermal hamartomas (primarily subcutaneous and visceral lipomas, multiple hemangiomas, and intestinal polyps). Dysmorphic features ...

Last Updated: 31 Dec 2013

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Bannayan Riley Ruvalcaba syndrome.
 

Author(s): Zarina Abdul Latiff, Raymond Warouw Atmawidjaja, Raja Juanita RajaLope, Sharifah Azween Syed Omar, Syed Zulkifli Syed Zakaria, Rahman A Jamal

Journal: Ann. Acad. Med. Singap.. 2010 Jul;39(7):578-2.

 

Last Updated: 10 Aug 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bannayan-Riley-Ruvalcaba Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.