Trachoma

Common Name(s)

Trachoma

Trachoma is one of the oldest infectious diseases known and is the world’s leading cause of preventable blindness of infectious origin. Trachoma is caused by the bacterium Chlamydia trachomatis and is spread through direct personal contact, shared towels or clothes, flies, and other things that have come in contact with an infected person. Risk factors include water shortage, flies, poor hygiene conditions, and crowded households. When left untreated after years of repeated infections, the inside of the eyelid may be scarred so severely that the eyelid turns inward and the lashes rub on the eyeball, scarring the cornea. This can cause pain, permanent damage to the cornea, and irreversible blindness. Trachoma is prevalent in a majority of the poorest and most remote rural areas of Africa, Asia, Central and South America, Australia, and the Middle East, often affecting women and children.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trachoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trachoma" returned 335 free, full-text research articles on human participants. First 3 results:

Last Updated: 26 Sep 2014

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The effect of multiple rounds of mass drug administration on the association between ocular Chlamydia trachomatis infection and follicular trachoma in preschool-aged children.
 

Author(s): Jennifer S Lee, Beatriz E Muñoz, Harran Mkocha, Charlotte A Gaydos, Thomas C Quinn, Sheila K West

Journal:

 

To examine the relationship between ocular Chlamydia trachomatis infection and follicular trachoma (TF) in children prior to and following multiple rounds of annual mass drug administration (MDA) with azithromycin.

Last Updated: 11 Apr 2014

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Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.
 

Author(s): Chrissy H Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M Harding-Esch, Sarah E Burr, David C W Mabey, Robin L Bailey, Matthew J Burton, Martin J Holland

Journal:

 

Chlamydia trachomatis is globally the predominant infectious cause of blindness and one of the most common bacterial causes of sexually transmitted infection. Infections of the conjunctiva cause the blinding disease trachoma, an immuno-pathological disease that is characterised by ...

Last Updated: 21 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trachoma" returned 23 free, full-text review articles on human participants. First 3 results:

Effect of water, sanitation, and hygiene on the prevention of trachoma: a systematic review and meta-analysis.
 

Author(s): Meredith E Stocks, Stephanie Ogden, Danny Haddad, David G Addiss, Courtney McGuire, Matthew C Freeman

Journal:

 

Trachoma is the world's leading cause of infectious blindness. The World Health Organization (WHO) has endorsed the SAFE strategy in order to eliminate blindness due to trachoma by 2020 through "surgery," "antibiotics," "facial cleanliness," and "environmental improvement." While ...

Last Updated: 3 Mar 2014

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The added value of water, sanitation, and hygiene interventions to mass drug administration for reducing the prevalence of trachoma: a systematic review examining.
 

Author(s): Anyess Travers, Sheryl Strasser, Stephanie L Palmer, Christine Stauber

Journal: J Environ Public Health. 2013 ;2013():682093.

 

Trachoma is the leading cause of infectious blindness worldwide. The SAFE strategy, the World Health Organization-recommended method to eliminate blinding trachoma, combines developments in water, sanitation, surgery, and antibiotic treatment. Current literature does not focus on ...

Last Updated: 30 Aug 2013

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Will the SAFE strategy be sufficient to eliminate trachoma by 2020? Puzzlements and possible solutions.
 

Author(s): Diane K Lavett, Van C Lansingh, Marissa J Carter, Kristen A Eckert, Juan C Silva

Journal:

 

Since the inception of (the Global Elimination of Blinding Trachoma) GET 2020 in 1997 and the implementation of the SAFE strategy a year later, much progress has been made toward lowering the prevalence of trachoma worldwide with elimination of the disease in some countries. However, ...

Last Updated: 14 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nepal Elimination of Trachoma Study
 

Status: Not yet recruiting

Condition Summary: Trachoma

 

Last Updated: 25 Jun 2014

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Last Updated: 25 Feb 2014

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Fluorometholone as Ancillary Therapy for TT Surgery
 

Status: Recruiting

Condition Summary: Trichiasis; Trachoma; Bilamellar Tarsal Rotation

 

Last Updated: 8 Nov 2013

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