Trachoma

Common Name(s)

Trachoma

Trachoma is one of the oldest infectious diseases known and is the world’s leading cause of preventable blindness of infectious origin. Trachoma is caused by the bacterium Chlamydia trachomatis and is spread through direct personal contact, shared towels or clothes, flies, and other things that have come in contact with an infected person. Risk factors include water shortage, flies, poor hygiene conditions, and crowded households. When left untreated after years of repeated infections, the inside of the eyelid may be scarred so severely that the eyelid turns inward and the lashes rub on the eyeball, scarring the cornea. This can cause pain, permanent damage to the cornea, and irreversible blindness. Trachoma is prevalent in a majority of the poorest and most remote rural areas of Africa, Asia, Central and South America, Australia, and the Middle East, often affecting women and children.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trachoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trachoma" returned 328 free, full-text research articles on human participants. First 3 results:

[Prevalence of trachoma in Brazilian schoolchildren].
 

Author(s): Maria de Fátima Costa Lopes, Expedito José de Albuquerque Luna, Norma Helen Medina, Maria Regina Alves Cardoso, Helen Selma de Abreu Freitas, Inês Kazue Koizumi, Neusa Aparecida Ferreira Alves Bernardes, José Alfredo Guimarães

Journal: Rev Saude Publica. 2013 Jun;47(3):451-9.

 

To estimate the prevalence and describe the distribution of trachoma among schoolchildren in Brazilian municipalities.

Last Updated: 18 Dec 2013

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Active trachoma two years after three rounds of azithromycin mass treatment in Cheha District Gurage Zone, Southern Ethiopia.
 

Author(s): Fisseha Admassu, Samson Bayu, Abebe Bejiga, Bemnet Amare

Journal:

 

Azithromycin mass distribution was given to residents of Gurage zone Cheha district in 2004, 2005 and 2006 for three consecutive years with more than 90% coverage. The effect of treatment in the study community was not yet determined. The present study was therefore designed to assess ...

Last Updated: 9 Dec 2013

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Zoonotic Chlamydiaceae species associated with trachoma, Nepal.
 

Author(s): Deborah Dean, James Rothschild, Anke Ruettger, Ram Prasad Kandel, Konrad Sachse

Journal: Emerging Infect. Dis.. 2013 Dec;19(12):1948-55.

 

Trachoma is the leading cause of preventable blindness. Commercial assays do not discriminate among all Chlamydiaceae species that might be involved in trachoma. We investigated whether a commercial Micro-ArrayTube could discriminate Chlamydiaceae species in DNA extracted directly ...

Last Updated: 26 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trachoma" returned 22 free, full-text review articles on human participants. First 3 results:

The added value of water, sanitation, and hygiene interventions to mass drug administration for reducing the prevalence of trachoma: a systematic review examining.
 

Author(s): Anyess Travers, Sheryl Strasser, Stephanie L Palmer, Christine Stauber

Journal: J Environ Public Health. 2013 ;2013():682093.

 

Trachoma is the leading cause of infectious blindness worldwide. The SAFE strategy, the World Health Organization-recommended method to eliminate blinding trachoma, combines developments in water, sanitation, surgery, and antibiotic treatment. Current literature does not focus on ...

Last Updated: 30 Aug 2013

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Will the SAFE strategy be sufficient to eliminate trachoma by 2020? Puzzlements and possible solutions.
 

Author(s): Diane K Lavett, Van C Lansingh, Marissa J Carter, Kristen A Eckert, Juan C Silva

Journal:

 

Since the inception of (the Global Elimination of Blinding Trachoma) GET 2020 in 1997 and the implementation of the SAFE strategy a year later, much progress has been made toward lowering the prevalence of trachoma worldwide with elimination of the disease in some countries. However, ...

Last Updated: 14 Jun 2013

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Trachoma: protective and pathogenic ocular immune responses to Chlamydia trachomatis.
 

Author(s): Victor H Hu, Martin J Holland, Matthew J Burton

Journal: PLoS Negl Trop Dis. 2013 ;7(2):e2020.

 

Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious blinding disease worldwide. Chronic conjunctival inflammation develops in childhood and leads to eyelid scarring and blindness in adulthood. The immune response to Ct provides only partial protection against ...

Last Updated: 4 Mar 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nepal Elimination of Trachoma Study
 

Status: Not yet recruiting

Condition Summary: Trachoma

 

Last Updated: 25 Jun 2014

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Fluorometholone as Ancillary Therapy for TT Surgery
 

Status: Recruiting

Condition Summary: Trichiasis; Trachoma; Bilamellar Tarsal Rotation

 

Last Updated: 8 Nov 2013

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Last Updated: 25 Feb 2014

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