Trachoma

Common Name(s)

Trachoma

Trachoma is one of the oldest infectious diseases known and is the world’s leading cause of preventable blindness of infectious origin. Trachoma is caused by the bacterium Chlamydia trachomatis and is spread through direct personal contact, shared towels or clothes, flies, and other things that have come in contact with an infected person. Risk factors include water shortage, flies, poor hygiene conditions, and crowded households. When left untreated after years of repeated infections, the inside of the eyelid may be scarred so severely that the eyelid turns inward and the lashes rub on the eyeball, scarring the cornea. This can cause pain, permanent damage to the cornea, and irreversible blindness. Trachoma is prevalent in a majority of the poorest and most remote rural areas of Africa, Asia, Central and South America, Australia, and the Middle East, often affecting women and children.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Trachoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Trachoma" returned 419 free, full-text research articles on human participants. First 3 results:

Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages.
 

Author(s): Patiyan Andersson, Simon R Harris, Helena M B Seth Smith, James Hadfield, Colette O'Neill, Lesley T Cutcliffe, Fiona P Douglas, L Valerie Asche, John D Mathews, Susan I Hutton, Derek S Sarovich, Steven Y C Tong, Ian N Clarke, Nicholas R Thomson, Philip M Giffard

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Chlamydia trachomatis causes sexually transmitted infections and the blinding disease trachoma. Current data on C. trachomatis phylogeny show that there is only a single trachoma-causing clade, which is distinct from the lineages causing urogenital tract (UGT) and lymphogranuloma ...

Last Updated: 25 Feb 2016

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Control of Trachoma from Achham District, Nepal: A Cross-Sectional Study from the Nepal National Trachoma Program.
 

Author(s): Bidya Prasad Pant, Ramesh C Bhatta, J S P Chaudhary, Suresh Awasthi, Sailesh Mishra, Shekhar Sharma, Puja A Cuddapah, Sarah E Gwyn, Nicole E Stoller, Diana L Martin, Jeremy D Keenan, Thomas M Lietman, Bruce D Gaynor

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The WHO seeks to control trachoma as a public health problem in endemic areas. Achham District in western Nepal was found to have TF (trachoma follicular) above 20% in a 2006 government survey, triggering 3 annual mass drug administrations finishing in 2010. Here we assess the level ...

Last Updated: 13 Feb 2016

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Can We Use Antibodies to Chlamydia trachomatis as a Surveillance Tool for National Trachoma Control Programs? Results from a District Survey.
 

Author(s): Sheila K West, Beatriz Munoz, Jerusha Weaver, Zakayo Mrango, Laura Dize, Charlotte Gaydos, Thomas C Quinn, Diana L Martin

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Trachoma is targeted for elimination by 2020. World Health Organization advises districts to undertake surveillance when follicular trachoma (TF) <5% in children 1-9 years and mass antibiotic administration has ceased. There is a question if other tools could be used for surveillance ...

Last Updated: 16 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Trachoma" returned 36 free, full-text review articles on human participants. First 3 results:

Historical Aspects of Endemic Trachoma in Peru: 1895-2000.
 

Author(s): Vicente Maco, Mayling Encalada, Carlos Wong, Luis A Marcos

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Last Updated: 15 Jan 2016

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Trachoma and Yaws: Common Ground?
 

Author(s): Anthony W Solomon, Michael Marks, Diana L Martin, Alexei Mikhailov, Rebecca M Flueckiger, Oriol Mitjà, Kingsley Asiedu, Jean Jannin, Dirk Engels, David C W Mabey

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Last Updated: 4 Dec 2015

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Interventions for trachoma trichiasis.
 

Author(s): Matthew Burton, Esmael Habtamu, Derek Ho, Emily W Gower

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Trachoma is the leading infectious cause of blindness. The World Health Organization (WHO) recommends eliminating trachomatous blindness through the SAFE strategy: Surgery for trichiasis, Antibiotic treatment, Facial cleanliness and Environmental hygiene. This is an update of a Cochrane ...

Last Updated: 15 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sanitation, Water, and Instruction in Face-washing for Trachoma
 

Status: Recruiting

Condition Summary: Trachoma

 

Last Updated: 5 May 2016

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Water Uptake for Health in Amhara Pilot
 

Status: Recruiting

Condition Summary: Trachoma

 

Last Updated: 20 Apr 2016

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Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
 

Status: Recruiting

Condition Summary: Infection; Hypertension; Pain; Reflux; Edema; Hyperlipidemia; Hypotension; Hypercholesterolemia; Sedation; Anxiolysis; Benzodiazepine Withdrawal; Bipolar Disorder; Autistic Disorder; Schizophrenia; Influenza Treatment or Prophylaxis; Acute Decompensated Heart Failure; Stable Angina; Life-threatening Fungal Infections; Nosocomial Pneumonia; Community Acquired Pneumonia; Acute Bacterial Exacerbation of Chronic Bronchitis; Complicated Skin and Skin Structure Infections; Uncomplicated Skin and Skin Structure Infections; Chronic Bacterial Prostatitis; Complicated Urinary Tract Infections; Acute Pyelonephritis; Uncomplicated Urinary Tract Infections; Inhalational Anthrax (Post-Exposure); Infantile Hemangioma; Withdrawal; Inflammation; Bacterial Septicemia; Cytomegalovirus Retinitis; Herpes Simplex Virus; Adenovirus; Brain Swelling; Airway Swelling; Adrenal Insufficiency; Anxiety; Nausea; Vomiting; Convulsions; Muscle Spasms; Seizures; Epilepsy; Bartonellosis; Brucellosis; Cholera; Plague; Psittacosis; Q Fever; Relapsing Fever; Rocky Mountain Spotted Fever; Trachoma; Tularemia; Typhus Fever; Bronchospasm; Cardiac Arrest; Hypersensitivity Reaction; Cyanide Poisoning; Acute Bacterial Sinusitis; Bacterial Meningitis; Sepsis; Gastroparesis; Opioid Addiction; Migraines; Headaches

 

Last Updated: 4 Feb 2016

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