Tourette syndrome

Common Name(s)

Tourette syndrome

Tourette syndrome (TS) is a disorder that causes uncontrollable body movements and sounds, called tics. Tics can vary from simple to complex. Simple tics tend to be sudden, short, less noticeable, and less frequent. Complex tics are frequent, obvious, and get in the way of communication and daily tasks. Tic types affect both movement (motor tics) and sound (vocal tics). Motor tics can cause an affected person to have repetitive eye blinking, eye twitching, shoulder shrugging, head jerking, jumping, hopping, or touching. More severe motor tics can include self-harm movements, like punching or hitting. Vocal tics can include repetitive throat clearing, sniffing, snorting, barking, grunting, and yelling, as well as repetitive words or phrases. Severe vocal tics include yelling inappropriate words, such as swearing (coprolalia), and repeating words or phrases of other people (echolalia). Some people with TS can have uncontrollable movements (spasms) of the vocal cords while speaking (spasmodic dysphonia). People with TS can also have other behavioral issues, including attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD).

The typical age of onset for TS is between 2 and 12 years. All ethnic groups can be affected, but males are affected more often than females. A family history of TS is also a risk factor. The exact cause of TS is unknown, but it is believed to be due to a combination of genetic and environmental factors. TS is usually diagnosed by a health professional who is trained in diagnosing mental health conditions, such as a psychologist or psychiatrist. Criteria in the Diagnostic and Statistical Manual of Mental Disorders (DSM) are used to diagnose TS. Currently there is no cure for TS, but treatments to help address symptoms include both medications and therapies. If your child has been diagnosed with TS, talk to their doctor about the most current treatment options and support groups.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette syndrome" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

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Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

Last Updated: 5 May 2014

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette syndrome" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

http://www.movementdisorders.org/MDS.htm

Last Updated: 5 May 2014

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

http://tsa-usa.org

Last Updated: 29 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tourette syndrome" returned 260 free, full-text research articles on human participants. First 3 results:

Difficulties experienced by young people with Tourette syndrome in secondary school: a mixed methods description of self, parent and staff perspectives.
 

Author(s): Ruth Wadman, Cris Glazebrook, Charlotte Beer, Georgina M Jackson

Journal:

 

Tourette syndrome (TS) is a neurodevelopmental disorder characterised by motor and vocal tics. These involuntary movements and vocalizations can have a negative impact in the school environment. The paper presents a mixed methods description of the difficulties experienced by UK students ...

Last Updated: 21 Jan 2016

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Gilles de la Tourette syndrome is not linked to contactin-associated protein receptor 2 antibodies.
 

Author(s): Kurt-Wolfram Sühs, Thomas Skripuletz, Refik Pul, Sascha Alvermann, Philipp Schwenkenbecher, Martin Stangel, Kirsten Müller-Vahl

Journal:

 

In Gilles de la Tourette syndrome (GTS) an immunopathogenic influence of autoantibodies is suspected. In familial GTS a disruption of the contactin-associated protein 2 gene (CNTNAP2), coding for the contactin-associated protein 2 (CASPR2), has been reported. Autoantibodies against ...

Last Updated: 14 Oct 2015

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Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population.
 

Author(s): Piotr Janik, Mariusz Berdyński, Krzysztof Safranow, Cezary Żekanowski

Journal:

 

Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder characterized by motor and vocal tics. Hyperactivity of dopaminergic transmission is considered a prime abnormality in the pathophysiology of tics. There are reciprocal antagonistic interactions between adenosine ...

Last Updated: 31 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tourette syndrome" returned 46 free, full-text review articles on human participants. First 3 results:

Abnormal neuronal activity in Tourette syndrome and its modulation using deep brain stimulation.
 

Author(s): Michal Israelashvili, Yocheved Loewenstern, Izhar Bar-Gad

Journal: J. Neurophysiol.. 2015 Jul;114(1):6-20.

 

Tourette syndrome (TS) is a common childhood-onset disorder characterized by motor and vocal tics that are typically accompanied by a multitude of comorbid symptoms. Pharmacological treatment options are limited, which has led to the exploration of deep brain stimulation (DBS) as ...

Last Updated: 3 Jul 2015

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Tourette Syndrome: Update.
 

Author(s): Mark Hallett

Journal: Brain Dev.. 2015 Aug;37(7):651-5.

 

Tourette Syndrome is a disorder characterized by tics. It typically begins in childhood and often improves in adult life. Tics are best described as voluntary movements made automatically so that volition is not ordinarily appreciated. There is frequently an urge, sometimes in the ...

Last Updated: 20 Jun 2015

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Prenatal risk factors for Tourette Syndrome: a systematic review.
 

Author(s): Ting-Kuang Chao, Jing Hu, Tamara Pringsheim

Journal:

 

Tourette Syndrome (TS) appears to be an inherited disorder, although genetic abnormalities have been identified in less than 1% of patients, and the mode of inheritance is uncertain. Many studies have investigated environmental factors that might contribute to the onset and severity ...

Last Updated: 11 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tourette Syndrome Deep Brain Stimulation
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 9 Jun 2016

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Sensory Processing in Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 9 Jun 2016

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Pilot Study for Use of Dysport in Treatment of Vocal Tics in Patients With Tourette's Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome; Chronic Vocal Tic

 

Last Updated: 9 Feb 2015

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