Thyroid Eye Disease

Common Name(s)

Thyroid Eye Disease

Thyroid eye disease can occur in people who already know they have thyroid disease, or it may be the first problem that brings people into the doctor's office. Symptoms of thyroid eye disease may include dry eyes, watery eyes, red eyes, or bulging eyes, as well as double vision or difficulty closing the eyes. Research suggests that the cause of thyroid eye disease is an autoimmune disorder. Treatment for this condition may be anti-inflammatory medications, radiation, or surgery.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Eye Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

Last Updated: 15 Jun 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Eye Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

http://www.gdatf.org

Last Updated: 15 Jun 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Eye Disease" returned 44 free, full-text research articles on human participants. First 3 results:

Correlation between Extraocular Muscle Size Measured by Computed Tomography and the Vertical Angle of Deviation in Thyroid Eye Disease.
 

Author(s): Ju-Yeun Lee, Kunho Bae, Kyung-Ah Park, In Jeong Lyu, Sei Yeul Oh

Journal:

 

The aim of this study was to investigate extraocular muscle (EOM) volume and cross-sectional area using computed tomography (CT), and to determine the relationship between EOM size and the vertical angle of deviation in thyroid eye disease (TED). Twenty-nine TED patients (58 orbits) ...

Last Updated: 29 Jan 2016

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The Role of the Immune Response in the Pathogenesis of Thyroid Eye Disease: A Reassessment.
 

Author(s): James T Rosenbaum, Dongseok Choi, Amanda Wong, David J Wilson, Hans E Grossniklaus, Christina A Harrington, Roger A Dailey, John D Ng, Eric A Steele, Craig N Czyz, Jill A Foster, David Tse, Chris Alabiad, Sander Dubovy, Prashant K Parekh, Gerald J Harris, Michael Kazim, Payal J Patel, Valerie A White, Peter J Dolman, Deepak P Edward, Hind M Alkatan, Hailah Al Hussain, Dinesh Selva, R Patrick Yeatts, Bobby S Korn, Don O Kikkawa, Patrick Stauffer, Stephen R Planck

Journal:

 

Although thyroid eye disease is a common complication of Graves' disease, the pathogenesis of the orbital disease is poorly understood. Most authorities implicate the immune response as an important causal factor. We sought to clarify pathogenesis by using gene expression microarray.

Last Updated: 16 Sep 2015

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Horizontal eye position in thyroid eye disease: a retrospective comparison with normal individuals and changes after orbital decompression surgery.
 

Author(s): Yasuhiro Takahashi, Hirohiko Kakizaki

Journal:

 

To compare horizontal eye positions between proptotic thyroid eye disease patients and normal individuals, and to examine positional changes after orbital decompression surgery in thyroid eye disease patients.

Last Updated: 4 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Eye Disease" returned 16 free, full-text review articles on human participants. First 3 results:

Critical Appraisal on Orbital Decompression for Thyroid Eye Disease: A Systematic Review and Literature Search.
 

Author(s): Konstadinos G Boboridis, Jimmy Uddin, Dimitrios G Mikropoulos, Catey Bunce, George Mangouritsas, Irini C Voudouragkaki, Anastasios G P Konstas

Journal: Adv Ther. 2015 Jul;32(7):595-611.

 

Orbital decompression is the indicated procedure for addressing exophthalmos and compressive optic neuropathy in thyroid eye disease. There are an abundance of techniques for removal of orbital bone, fat, or a combination published in the scientific literature. The relative efficacy ...

Last Updated: 3 Aug 2015

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Management of strabismus in thyroid eye disease.
 

Author(s): R Harrad

Journal: Eye (Lond). 2015 Feb;29(2):234-7.

 

Thyroid eye disease is an auto-immune condition characterised by an acute inflammatory phase followed by a fibrotic phase, which sometimes leads to restricted eye movements and diplopia. Medical treatment with systemic steroids with or without orbital radiotherapy and immunosuppression ...

Last Updated: 12 Feb 2015

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Thyroid eye disease.
 

Author(s): Michel J Belliveau, David R Jordan

Journal: CMAJ. 2013 Jun;185(9):797.

 

Last Updated: 11 Jun 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease
 

Status: Recruiting

Condition Summary: Thyroid Eye Disease

 

Last Updated: 10 May 2016

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The Effect of a New Antioxidant Combination (ASTED) on Mild Thyroid Eye Disease (TED)
 

Status: Not yet recruiting

Condition Summary: Thyroid Eye Disease

 

Last Updated: 9 Mar 2016

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The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.
 

Status: Not yet recruiting

Condition Summary: Thyroid Eye Disease; Ocular Hypertension; Glaucoma

 

Last Updated: 19 Aug 2013

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