Thyroid Eye Disease

Common Name(s)

Thyroid Eye Disease

Thyroid eye disease can occur in people who already know they have thyroid disease, or it may be the first problem that brings people into the doctor's office. Symptoms of thyroid eye disease may include dry eyes, watery eyes, red eyes, or bulging eyes, as well as double vision or difficulty closing the eyes. Research suggests that the cause of thyroid eye disease is an autoimmune disorder. Treatment for this condition may be anti-inflammatory medications, radiation, or surgery.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Eye Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

Last Updated: 9 Oct 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Eye Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

http://www.gdatf.org

Last Updated: 9 Oct 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Eye Disease" returned 33 free, full-text research articles on human participants. First 3 results:

An abscess causing a delayed optic neuropathy after decompression for thyroid eye disease.
 

Author(s): Rakesh M Patel, Vinay K Aakalu, Stephanie Joe, Pete Setabutr

Journal: Orbit. 2014 Feb;33(1):65-7.

 

A 63-year-old female with Graves' disease and chronic sinusitis presented with acute left orbital pain and proptosis five years after bilateral orbital decompression and sinus surgery. Imaging revealed bilateral frontal sinus opacification, frontoethmoidal mucoceles and left subperiosteal ...

Last Updated: 9 Jan 2014

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Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype.
 

Author(s): Ajay E Kuriyan, Collynn F Woeller, Charles W O'Loughlin, Richard P Phipps, Steven E Feldon

Journal:

 

Thyroid eye disease (TED) patients are classified as type I (predominantly fat compartment enlargement) or type II (predominantly extraocular muscle enlargement) based on orbital imaging. Orbital fibroblasts (OFs) can be driven to proliferate or differentiate into adipocytes in vitro. ...

Last Updated: 11 Nov 2013

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Beyond a typical thyroid eye disease.
 

Author(s): Mohsen Bahmani Kashkouli

Journal: Middle East Afr J Ophthalmol. ;20(3):185-6.

 

Last Updated: 9 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Eye Disease" returned 14 free, full-text review articles on human participants. First 3 results:

Thyroid eye disease.
 

Author(s): Michel J Belliveau, David R Jordan

Journal: CMAJ. 2013 Jun;185(9):797.

 

Last Updated: 11 Jun 2013

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Acute thyroid eye disease (TED): principles of medical and surgical management.
 

Author(s): D H Verity, G E Rose

Journal: Eye (Lond). 2013 Mar;27(3):308-19.

 

The active inflammatory phase of thyroid eye disease (TED) is mediated by the innate immune system, and management is aimed at aborting this self-limited period of autoimmune activity. In most patients with TED, ocular and adnexal changes are mild and management involves controlling ...

Last Updated: 14 Mar 2013

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Thyroid eye disease: towards an evidence base for treatment in the 21st century.
 

Author(s): Erin F Gillespie, Terry J Smith, Raymond S Douglas

Journal: Curr Neurol Neurosci Rep. 2012 Jun;12(3):318-24.

 

Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves' disease. Incomplete understanding of its pathogenesis has hindered development of targeted therapies that might alter the natural course of disease. Smoking cessation and maintenance of euthyroidism ...

Last Updated: 3 May 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tocilizumab Treatment in Graves´ Ophthalmopathy (Graves´ Orbitopathy or Thyroid Eye Disease)
 

Status: Recruiting

Condition Summary: Thyroid Associated Ophthalmopathies; Graves´ Ophthalmopathy; Thyroid Eye Disease

 

Last Updated: 23 Jul 2014

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Teprotumumab Treatment in Patients With Active Thyroid Eye Disease
 

Status: Recruiting

Condition Summary: Thyroid Associated Ophthalmopathies; Thyroid-Associated Ophthalmopathy

 

Last Updated: 13 Nov 2014

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Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease
 

Status: Recruiting

Condition Summary: Thyroid Eye Disease

 

Last Updated: 2 Dec 2014

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