Thyroid cancer, follicular

Common Name(s)

Thyroid cancer, follicular

Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin and accounts for more than 95% of all thyroid cancer cases (summary by {15:Vriens et al., 2009}). The remaining cancers originate from parafollicular cells (medullary thyroid cancer, MTC; {155240}). NMTC is classified into 4 groups: papillary ({188550}), follicular, Hurthle cell ({607464}), and anaplastic. Approximately 5% of NMTC is hereditary, occurring as a minor component of a familial cancer syndrome (e.g., familial adenomatous polyposis {175100}, Carney complex {160980}) or as a primary feature (familial NMTC or FNMTC). Papillary thyroid cancer (PTC) is the most common histologic subtype of FNMTC, accounting for approximately 85% of cases. Follicular thyroid cancer (FTC) accounts for approximately 15% of NMTC and is defined by invasive features that result in infiltration of blood vessels and/or full penetration of the tumor capsule, in the absence of the nuclear alterations that characterize papillary carcinoma (summary by {3:Bonora et al., 2010}). FTC is rarely multifocal and usually does not metastasize to the regional lymph nodes but tends to spread via the bloodstream to the lung and bones. An important histologic variant of FTC is the oncocytic (Hurthle cell, oxyphilic) follicular carcinoma composed of eosinophilic cells replete with mitochondria.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid cancer, follicular" for support, advocacy or research.

ThyCa: Thyroid Cancer Survivors' Association, Inc.

* To Educate, so we and our families better understand our disease. * To Participate, so others learn from our experience. * To Communicate, so we and our health care professionals better understand each others' needs. * To Support Research, for a future free of thyroid cancer.

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid cancer, follicular" for support, advocacy or research.

ThyCa: Thyroid Cancer Survivors' Association, Inc.

* To Educate, so we and our families better understand our disease. * To Participate, so others learn from our experience. * To Communicate, so we and our health care professionals better understand each others' needs. * To Support Research, for a future free of thyroid cancer.

http://www.thyca.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid cancer, follicular" returned 0 free, full-text research articles on human participants.

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid cancer, follicular" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Cediranib Maleate With or Without Lenalidomide in Treating Patients With Thyroid Cancer
 

Status: Recruiting

Condition Summary: Recurrent Thyroid Cancer; Stage I Follicular Thyroid Cancer; Stage I Papillary Thyroid Cancer; Stage II Follicular Thyroid Cancer; Stage II Papillary Thyroid Cancer; Stage III Follicular Thyroid Cancer; Stage III Papillary Thyroid Cancer; Stage IVA Follicular Thyroid Cancer; Stage IVA Papillary Thyroid Cancer; Stage IVB Follicular Thyroid Cancer; Stage IVB Papillary Thyroid Cancer; Stage IVC Follicular Thyroid Cancer; Stage IVC Papillary Thyroid Cancer

 

Last Updated: 28 Jul 2014

Go to URL
Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer
 

Status: Recruiting

Condition Summary: Insular Thyroid Cancer; Recurrent Thyroid Cancer; Stage I Follicular Thyroid Cancer; Stage I Papillary Thyroid Cancer; Stage II Follicular Thyroid Cancer; Stage II Papillary Thyroid Cancer; Stage III Follicular Thyroid Cancer; Stage III Papillary Thyroid Cancer; Stage IVA Follicular Thyroid Cancer; Stage IVA Papillary Thyroid Cancer; Stage IVB Follicular Thyroid Cancer; Stage IVB Papillary Thyroid Cancer; Stage IVC Follicular Thyroid Cancer; Stage IVC Papillary Thyroid Cancer

 

Last Updated: 4 Aug 2014

Go to URL
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Thyroid Cancer
 

Status: Not yet recruiting

Condition Summary: Recurrent Thyroid Cancer; Stage III Follicular Thyroid Cancer; Stage IVA Follicular Thyroid Cancer; Stage IVB Follicular Thyroid Cancer; Stage IVC Follicular Thyroid Cancer

 

Last Updated: 22 May 2014

Go to URL