Thrombocytopenia, x-linked

Common Name(s)

Thrombocytopenia, x-linked

Hereditary nonsyndromic thrombocytopenia is characterized by decreased numbers of platelets and bleeding tendency (summary by {12:Villa et al., 1995}). Genetic Heterogeneity of Hereditary Thrombocytopenia Autosomal dominant forms of thrombocytopenia include THC2 ({188000}), caused by mutation in the ANKRD26 ({610855}) gene on chromosome 10; THC4 ({612004}), caused by mutation in the CYCS gene ({123970}) on chromosome 7; and THC5 ({616216}), caused by mutation in the ETV6 gene ({600618}) on chromosome 12p13. A possible autosomal recessive form also exists (THC3; {273900}). Also see {188000} for discussion of a possible form of THC caused by mutation in the MASTL gene ({608221}) on chromosome 10. {2:Balduini and Savoia (2012)} reviewed the familial forms of thrombocytopenia and their molecular bases.
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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thrombocytopenia, x-linked" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Recommended Apps

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Thrombocytopenia, x-linked can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thrombocytopenia, x-linked" returned 0 free, full-text research articles on human participants.

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Review articles summarize what is currently known about a disease. They discuss research previously published by others.
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
http://ghr.nlm.nih.gov/condition/x-linked-thrombocytopenia
Full Results at Genetics Home Reference: 7 matches
This information is provided by GeneReviews.
http://www.ncbi.nlm.nih.gov/books/NBK1178
This information is provided by Genetic Testing Registry.
http://www.ncbi.nlm.nih.gov/gtr/conditions/C1839163
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Interleukin-2 Treatment for Wiskott-Aldrich Syndrome
 

Status: Recruiting

Condition Summary: Wiskott-Aldrich Syndrome (WAS); X-linked Thrombocytopenia

 

Last Updated: 11 Jan 2015

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Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
 

Status: Recruiting

Condition Summary: Sickle Cell Disease; Thalassemia; Anemia; Granuloma; Wiskott-Aldrich Syndrome; Chediak Higashi Syndrome; Osteopetrosis; Neutropenia; Thrombocytopenia; Hurler Disease; Niemann-Pick Disease; Fucosidosis

 

Last Updated: 22 Jun 2011

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Thrombocytopenia and Bleeding in Wiskott-Aldrich Syndrome (WAS) Patients
 

Status: Recruiting

Condition Summary: Wiskott-Aldrich Syndrome; Thrombocytopenia; Bleeding

 

Last Updated: 20 Nov 2012

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According to ClinicalTrials.gov there are currently 3 additional "open" studies for "Thrombocytopenia, x-linked" (open studies are recruiting volunteers) and 7 "Thrombocytopenia, x-linked" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
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Relief is when you and the right researcher find each other
Finding the right clinical trial for Thrombocytopenia, x-linked can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More