Thrombasthenia

Common Name(s)

Thrombasthenia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thrombasthenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thrombasthenia" returned 108 free, full-text research articles on human participants. First 3 results:

Acquired thrombasthenia due to inhibitory effect of glycoprotein IIbIIIa autoantibodies.
 

Author(s): Dorit Blickstein, Rima Dardik, Esther Rosenthal, Judith Lahav, Yair Molad, Aida Inbal

Journal: Isr. Med. Assoc. J.. 2014 May;16(5):307-10.

 

A 75 year old patient presenting with mucocutaneous bleeding was diagnosed with acquired thrombasthenia. The diagnosis was based on lack of platelet aggregation with adenosine diphosphate (ADP), arachidonic acid and collagen, and normal aggregation induced by ristocetin.

Last Updated: 1 Jul 2014

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Clinical utility gene card for: Glanzmann thrombasthenia.
 

Author(s): Mathieu Fiore, Alan T Nurden, Paquita Nurden, Uri Seligsohn

Journal: Eur. J. Hum. Genet.. 2012 Oct;20(10):.

 

Last Updated: 20 Sep 2012

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[Pregnancy and delivery in a patient with Glanzmann's thrombasthenia].
 

Author(s): Anis Fadhlaoui, Naouel Ben Salah, Mohamed Khrouf, Moncef Boubaker, Emna Gouider, Fethi Zhioua, Anis Chaker

Journal: Tunis Med. 2011 Dec;89(12):951-2.

 

Last Updated: 26 Dec 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thrombasthenia" returned 9 free, full-text review articles on human participants. First 3 results:

Glanzmann thrombasthenia: state of the art and future directions.
 

Author(s): Alan T Nurden, Xavier Pillois, David A Wilcox

Journal: Semin. Thromb. Hemost.. 2013 Sep;39(6):642-55.

 

Glanzmann thrombasthenia (GT) is the principal inherited disease of platelets and the most commonly encountered disorder of an integrin. GT is characterized by spontaneous mucocutaneous bleeding and an exaggerated response to trauma caused by platelets that fail to aggregate when ...

Last Updated: 28 Aug 2013

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Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models.
 

Author(s): Alan T Nurden, Mathieu Fiore, Paquita Nurden, Xavier Pillois

Journal: Blood. 2011 Dec;118(23):5996-6005.

 

Characterized by mucocutaneous bleeding arising from a lack of platelet aggregation to physiologic stimuli, Glanzmann thrombasthenia (GT) is the archetype-inherited disorder of platelets. Transmitted by autosomal recessive inheritance, platelets in GT have quantitative or qualitative ...

Last Updated: 2 Dec 2011

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[Glanzmann's thrombasthenia and pregnancy: report of a case and literature review].
 

Author(s): Myriam Rachad, Hikmat Chaara, Fatim zahra Fdili, Sofia Jayi, Hakimat Bouguern, Moulay Abdelilah Melhouf

Journal: Pan Afr Med J. 2011 ;10():61.

 

Last Updated: 2 Mar 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Abatacept Reduced Intensity for Non-Malignant Diseases
 

Status: Recruiting

Condition Summary: Hurler Syndrome; Fanconi Anemia; Glanzmann Thrombasthenia; Wiskott-Aldrich Syndrome; Chronic Granulomatous Disease; Severe Congenital Neutropenia; Leukocyte Adhesion Deficiency; Shwachman Diamond Syndrome; Diamond Blackfan Anemia; Dyskeratosis Congenita; Chediak Higashi Syndrome; Severe Aplastic Anemia; Thalassemia; Hemophagocytic Lymphohistiocytosis

 

Last Updated: 13 Mar 2014

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Last Updated: 5 May 2014

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