Tetraploidy

Common Name(s)

Tetraploidy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetraploidy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetraploidy" returned 25 free, full-text research articles on human participants. First 3 results:

Two cases of near-tetraploidy in acute leukemias of ambiguous lineage.
 

Author(s): Bo Hyun Kim, Hye Ryoun Kim, Mi-Kyung Lee, Hyunyoung Chi

Journal: Ann Lab Med. 2013 Sep;33(5):371-4.

 

Last Updated: 4 Sep 2013

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Tetraploidy in hydatidiform moles.
 

Author(s): Linda Sundvall, Helle Lund, Isa Niemann, Uffe Birk Jensen, Lars Bolund, Lone Sunde

Journal: Hum. Reprod.. 2013 Jul;28(7):2010-20.

 

How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins?

Last Updated: 19 Jun 2013

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Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints.
 

Author(s): Stephan C Jahn, Patrick E Corsino, Bradley J Davis, Mary E Law, Peter Nørgaard, Brian K Law

Journal: J. Cell. Sci.. 2013 Mar;126(Pt 5):1207-17.

 

The cell has many mechanisms for protecting the integrity of its genome. These mechanisms are often weakened or absent in many cancers, leading to high rates of chromosomal instability in tumors. Control of the cell cycle is crucial for the function of these checkpoints, and is frequently ...

Last Updated: 26 Apr 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetraploidy" returned 3 free, full-text review articles on human participants. First 3 results:

A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR).
 

Author(s): José M Frade, Noelia López-Sánchez

Journal: Cell Cycle. 2010 May;9(10):1934-41.

 

Cumulative evidence indicates that neuronal cell cycle re-entry represents an early and critical event in AD, recapitulating known hallmarks of the disease including tau hyperphosphorylation and production of Aβ peptide-containing plaques. Neurons that duplicate their DNA are rarely ...

Last Updated: 11 Jan 2011

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The consequences of tetraploidy and aneuploidy.
 

Author(s): Zuzana Storchova, Christian Kuffer

Journal: J. Cell. Sci.. 2008 Dec;121(Pt 23):3859-66.

 

Polyploidy, an increased number of chromosome sets, is a surprisingly common phenomenon in nature, particularly in plants and fungi. In humans, polyploidy often occurs in specific tissues as part of terminal differentiation. Changes in ploidy can also result from pathophysiological ...

Last Updated: 21 Nov 2008

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Tetraploidy in a liveborn infant.
 

Author(s): I López Pajares, A Delicado, A Diaz de Bustamante, A Pellicer, I Pinel, M Pardo, M Martin

Journal: J. Med. Genet.. 1990 Dec;27(12):782-3.

 

We report a 3 month old boy with tetraploidy, found in peripheral blood and skin fibroblast cultures, with severely delayed growth and neurodevelopment, and with a cleft lip; these findings have not been described before. This report brings to seven the total number of liveborn infants ...

Last Updated: 12 Apr 1991

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.