Tetanus

Common Name(s)

Tetanus

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 741 free, full-text research articles on human participants. First 3 results:

Validation of maternal and neonatal tetanus elimination in Cameroon, 2012.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2013 Nov;88(46):489-99.

 

Last Updated: 15 Nov 2013

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Validation of maternal and neonatal tetanus elimination in United Republic of Tanzania, 2012.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2013 Jul;88(30):313-20.

 

Last Updated: 2 Aug 2013

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Randomized, controlled, multicenter study of the immunogenicity and safety of a fully liquid combination diphtheria-tetanus toxoid-five-component acellular pertussis (DTaP5), inactivated poliovirus (IPV), and haemophilus influenzae type b (Hib) vaccine compared with a DTaP3-IPV/Hib vaccine administered at 3, 5, and 12 months of age.
 

Author(s): Timo Vesikari, Sven Arne Silfverdal, Florence Boisnard, Stéphane Thomas, Grace Mwawasi, Donna Reynolds

Journal: Clin. Vaccine Immunol.. 2013 Oct;20(10):1647-53.

 

This study compared the levels of immunogenicity and safety of diphtheria-tetanus toxoid-five-component acellular pertussis (DTaP(5)), inactivated poliovirus (IPV), and Haemophilus influenzae type b (Hib) (DTaP(5)-IPV-Hib) and DTaP(3)-IPV/Hib vaccines for study participants 3, 5, ...

Last Updated: 27 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 27 free, full-text review articles on human participants. First 3 results:

Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries--a systematic review.
 

Author(s): Adeel Ahmed Khan, Aysha Zahidie, Fauziah Rabbani

Journal:

 

In 1988, WHO estimated around 787,000 newborns deaths due to neonatal tetanus. Despite few success stories majority of the Low and Middle Income Countries (LMICs) are still struggling to reduce neonatal mortality due to neonatal tetanus. We conducted a systematic review to understand ...

Last Updated: 29 Apr 2013

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Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms.
 

Author(s): Bjørnar Hassel

Journal:

 

Tetanus toxin, the product of Clostridium tetani, is the cause of tetanus symptoms. Tetanus toxin is taken up into terminals of lower motor neurons and transported axonally to the spinal cord and/or brainstem. Here the toxin moves trans-synaptically into inhibitory nerve terminals, ...

Last Updated: 9 Jan 2013

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Neonatal tetanus elimination in Pakistan: progress and challenges.
 

Author(s): Jonathan A Lambo, Tharsiya Nagulesapillai

Journal: Int. J. Infect. Dis.. 2012 Dec;16(12):e833-42.

 

Pakistan is one of the 34 countries that have not achieved the neonatal tetanus (NT) global elimination target set by the World Health Organization (WHO). NT, caused by Clostridium tetani, is a highly fatal infection of the neonatal period. It is one of the most underreported diseases ...

Last Updated: 19 Nov 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Post Marketing Surveillance for ADACEL™ in South Korea
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis

 

Last Updated: 16 Jan 2014

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Regulatory Post-Marketing Surveillance Study for TETRAXIM™
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 10 Feb 2014

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Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis

 

Last Updated: 11 Jun 2014

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