Tetanus

Common Name(s)

Tetanus, Lockjaw

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 746 free, full-text research articles on human participants. First 3 results:

Assessment of tetanus immunity status by tetanus quick stick and anamnesis: a prospective double blind study.
 

Author(s): G B Orsi, C Modini, M A Principe, M Di Muzio, A Moriconi, M G Amato, S M Calderale

Journal: Ann Ig. ;27(2):467-74.

 

In patients with wounds admitted to Emergency Departments (ED) acquiring tetanus vaccination history by interview is very unreliable. Protected patients may receive unnecessary prophylaxis and unprotected nothing. Aim of the study was to evaluate tetanus immunity status comparing ...

Last Updated: 8 Jun 2015

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Tetanus, diphtheria, pertussis vaccination coverage before, during, and after pregnancy - 16 States and New York City, 2011.
 

Author(s): Indu B Ahluwalia, Helen Ding, Denise D'Angelo, Kristen H Shealy, James A Singleton, Jennifer Liang, Kenneth D Rosenberg,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 May;64(19):522-6.

 

In June 2011, the Advisory Committee on Immunizations Practices (ACIP) recommended 1 dose of a tetanus, diphtheria, and acellular pertussis (Tdap) vaccine during pregnancy for women who had not received Tdap previously. Before 2011, Tdap was recommended for unvaccinated women either ...

Last Updated: 22 May 2015

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Missed opportunities for tetanus postexposure prophylaxis--California, January 2008-March 2014.
 

Author(s): Cynthia Yen, Erin Murray, Jennifer Zipprich, Kathleen Winter, Kathleen Harriman,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Mar;64(9):243-6.

 

Tetanus is an acute and sometimes fatal disease characterized by sudden muscle contractions. The number of tetanus cases reported annually in the United States has declined significantly since the 1930s and 1940s as a result of the introduction of tetanus vaccines. However, sporadic ...

Last Updated: 13 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 29 free, full-text review articles on human participants. First 3 results:

Prognostic factors for mortality in neonatal tetanus: a systematic review and meta-analysis.
 

Author(s): Jonathan A Lambo, Emmanuel A Anokye

Journal: Int. J. Infect. Dis.. 2013 Dec;17(12):e1100-10.

 

To determine prognostic factors for mortality in neonates with tetanus and to assess the associations between prognostic factors and neonatal tetanus (NT) mortality.

Last Updated: 2 Dec 2013

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Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type B vaccine; Infanrix™ hexa: twelve years of experience in Italy.
 

Author(s): Vincenzo Baldo, Paolo Bonanni, Marcela Castro, Giovanni Gabutti, Elisabetta Franco, Federico Marchetti, Rosa Prato, Francesco Vitale

Journal: Hum Vaccin Immunother. 2014 ;10(1):129-37.

 

Infant vaccination using 2-dose priming at 3 and 5 mo of age with a booster at 11-12 mo of age was pioneered in Italy. The 3-5-11 schedule is now used in a growing number of European countries. Infanrix™ hexa (DTPa-HBV-IPV/Hib, GlaxoSmithKline Vaccines) was first licensed for use ...

Last Updated: 16 May 2014

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Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries--a systematic review.
 

Author(s): Adeel Ahmed Khan, Aysha Zahidie, Fauziah Rabbani

Journal:

 

In 1988, WHO estimated around 787,000 newborns deaths due to neonatal tetanus. Despite few success stories majority of the Low and Middle Income Countries (LMICs) are still struggling to reduce neonatal mortality due to neonatal tetanus. We conducted a systematic review to understand ...

Last Updated: 29 Apr 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vaccine -diphthEria -tetaNus -Acellular pertUssis-inactivated polioviruS
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 28 May 2015

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Post Marketing Surveillance for ADACEL™ in South Korea
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis

 

Last Updated: 11 Feb 2015

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Regulatory Post-Marketing Surveillance Study for TETRAXIM™
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 1 Mar 2015

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