Tetanus

Common Name(s)

Tetanus, Lockjaw

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 973 free, full-text research articles on human participants. First 3 results:

Maternal and neonatal tetanus validation assessment in Region 4, Indonesia, May 2016.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2016 Jun;91(25):317-28.

 

Last Updated: 27 Jun 2016

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Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen.
 

Author(s): Diana Klose, Ute Saunders, Stefan Barth, Rainer Fischer, Annett Marita Jacobi, Thomas Nachreiner

Journal:

 

In an earlier study we developed a unique strategy allowing us to specifically eliminate antigen-specific murine B cells via their distinct B cell receptors using a new class of fusion proteins. In the present work we elaborated our idea to demonstrate the feasibility of specifically ...

Last Updated: 17 Feb 2016

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The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.
 

Author(s): Daphné Laubreton, Sylvie Bay, Christine Sedlik, Cécile Artaud, Christelle Ganneau, Edith Dériaud, Sophie Viel, Anne-Laure Puaux, Sebastian Amigorena, Catherine Gérard, Richard Lo-Man, Claude Leclerc

Journal: Cancer Immunol. Immunother.. 2016 Mar;65(3):315-25.

 

Malignant transformations are often associated with aberrant glycosylation processes that lead to the expression of new carbohydrate antigens at the surface of tumor cells. Of these carbohydrate antigens, the Tn antigen is particularly highly expressed in many carcinomas, especially ...

Last Updated: 5 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 34 free, full-text review articles on human participants. First 3 results:

Eradication of tetanus.
 

Author(s): C L Thwaites, H T Loan

Journal: Br. Med. Bull.. 2015 ;116():69-77.

 

The causative agent of tetanus, Clostridium tetani is widespread in the environment throughout the world and cannot be eradicated. To reduce the number of cases of tetanus efforts are focussed on prevention using vaccination and post-exposure wound care.

Last Updated: 15 Dec 2015

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Pharmacological management of tetanus: an evidence-based review.
 

Author(s): Chaturaka Rodrigo, Deepika Fernando, Senaka Rajapakse

Journal:

 

Tetanus is becoming rarer in both industrialized and developing nations due to an effective vaccination program. In 2010, the World Health Organization estimated there was a 93% reduction in newborns dying from tetanus worldwide, compared to the situation in the late 1980s. Due to ...

Last Updated: 21 Jul 2014

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Prognostic factors for mortality in neonatal tetanus: a systematic review and meta-analysis.
 

Author(s): Jonathan A Lambo, Emmanuel A Anokye

Journal: Int. J. Infect. Dis.. 2013 Dec;17(12):e1100-10.

 

To determine prognostic factors for mortality in neonates with tetanus and to assess the associations between prognostic factors and neonatal tetanus (NT) mortality.

Last Updated: 2 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vaccine -diphthEria -tetaNus -Acellular pertUssis-inactivated polioviruS
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 14 Jun 2016

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Safety and Efficacy of Two Tetanus-Diphtheria Vaccines for a Donor Hyper Immunization Program
 

Status: Not yet recruiting

Condition Summary: Healthy

 

Last Updated: 22 Jul 2016

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