Tetanus

Common Name(s)

Tetanus, Lockjaw

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 932 free, full-text research articles on human participants. First 3 results:

Last Updated: 30 Oct 2015

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Licensure of a Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine and Guidance for Use as a Booster Dose.
 

Author(s): Jennifer Liang, Greg Wallace, Gina Mootrey

Journal:

 

On March 24, 2015, the Food and Drug Administration licensed an additional combined diphtheria and tetanus toxoids and acellular pertussis adsorbed (DTaP) and inactivated poliovirus (IPV) vaccine (DTaP-IPV) (Quadracel, Sanofi Pasteur Inc.). Quadracel is the second DTaP-IPV vaccine ...

Last Updated: 4 Sep 2015

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Tetanus in Poland in 2013.
 

Author(s): Andrzej Zieliński, Jolanta Rudowska

Journal: Przegl Epidemiol. 2015 ;69(2):263-5, 379-80.

 

Tetanus is an infectious disease which, despite the small number of cases is a permanent risk to unvaccinated people. The severity of disease is associated with high mortality especially in older age groups.

Last Updated: 3 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 31 free, full-text review articles on human participants. First 3 results:

Pharmacological management of tetanus: an evidence-based review.
 

Author(s): Chaturaka Rodrigo, Deepika Fernando, Senaka Rajapakse

Journal:

 

Tetanus is becoming rarer in both industrialized and developing nations due to an effective vaccination program. In 2010, the World Health Organization estimated there was a 93% reduction in newborns dying from tetanus worldwide, compared to the situation in the late 1980s. Due to ...

Last Updated: 21 Jul 2014

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Prognostic factors for mortality in neonatal tetanus: a systematic review and meta-analysis.
 

Author(s): Jonathan A Lambo, Emmanuel A Anokye

Journal: Int. J. Infect. Dis.. 2013 Dec;17(12):e1100-10.

 

To determine prognostic factors for mortality in neonates with tetanus and to assess the associations between prognostic factors and neonatal tetanus (NT) mortality.

Last Updated: 2 Dec 2013

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Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type B vaccine; Infanrix™ hexa: twelve years of experience in Italy.
 

Author(s): Vincenzo Baldo, Paolo Bonanni, Marcela Castro, Giovanni Gabutti, Elisabetta Franco, Federico Marchetti, Rosa Prato, Francesco Vitale

Journal: Hum Vaccin Immunother. 2014 ;10(1):129-37.

 

Infant vaccination using 2-dose priming at 3 and 5 mo of age with a booster at 11-12 mo of age was pioneered in Italy. The 3-5-11 schedule is now used in a growing number of European countries. Infanrix™ hexa (DTPa-HBV-IPV/Hib, GlaxoSmithKline Vaccines) was first licensed for use ...

Last Updated: 16 May 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vaccine -diphthEria -tetaNus -Acellular pertUssis-inactivated polioviruS
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 28 May 2015

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Post Marketing Surveillance for ADACEL™ in South Korea
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis

 

Last Updated: 17 Aug 2015

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Post-marketing Surveillance to Assess the Safety of Infanrix-IPV Vaccine Among Infants and Children in Korea
 

Status: Recruiting

Condition Summary: Acellular Pertussis; Diphtheria; Tetanus; Poliomyelitis

 

Last Updated: 20 Jul 2015

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