Tetanus

Common Name(s)

Tetanus

Tetanus, also called "lockjaw", is a disease caused by a bacterial infection from Clostridium tetani which can be found in dirt, dust, or animal feces. Infection occurs from contact with the bacteria through open skin wounds. The bacteria affects muscular activity, and can cause spasms, stiffness, and other discomfort. There is a tetanus vaccine available and a booster shot that you can receive if you have a deep or dirty wound. Treatment given usually includes wound care, antibiotics, and bedrest.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tetanus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tetanus" returned 745 free, full-text research articles on human participants. First 3 results:

Maternal and neonatal tetanus elimination: validation survey in 4 States in India, April 2013.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2014 May;89(18):177-88.

 

Last Updated: 23 May 2014

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Validation of maternal and neonatal tetanus elimination in Cameroon, 2012.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2013 Nov;88(46):489-99.

 

Last Updated: 15 Nov 2013

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Subnormal and waning immunity to tetanus toxoid in previously vaccinated HIV-infected children and response to booster doses of the vaccine.
 

Author(s): Shahana A Choudhury, Fazle Matin

Journal: Int. J. Infect. Dis.. 2013 Dec;17(12):e1249-51.

 

Little is known regarding waning immunity to tetanus toxoid (TT) in HIV-infected children and the need for booster doses before the recommended interval of 5-10 years. Anti-tetanus antibodies were assessed by ELISA in 24 HIV-infected and 24 control children. A protective level (>0.1 ...

Last Updated: 2 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tetanus" returned 28 free, full-text review articles on human participants. First 3 results:

Prognostic factors for mortality in neonatal tetanus: a systematic review and meta-analysis.
 

Author(s): Jonathan A Lambo, Emmanuel A Anokye

Journal: Int. J. Infect. Dis.. 2013 Dec;17(12):e1100-10.

 

To determine prognostic factors for mortality in neonates with tetanus and to assess the associations between prognostic factors and neonatal tetanus (NT) mortality.

Last Updated: 2 Dec 2013

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Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries--a systematic review.
 

Author(s): Adeel Ahmed Khan, Aysha Zahidie, Fauziah Rabbani

Journal:

 

In 1988, WHO estimated around 787,000 newborns deaths due to neonatal tetanus. Despite few success stories majority of the Low and Middle Income Countries (LMICs) are still struggling to reduce neonatal mortality due to neonatal tetanus. We conducted a systematic review to understand ...

Last Updated: 29 Apr 2013

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Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms.
 

Author(s): Bjørnar Hassel

Journal:

 

Tetanus toxin, the product of Clostridium tetani, is the cause of tetanus symptoms. Tetanus toxin is taken up into terminals of lower motor neurons and transported axonally to the spinal cord and/or brainstem. Here the toxin moves trans-synaptically into inhibitory nerve terminals, ...

Last Updated: 9 Jan 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Post Marketing Surveillance for ADACEL™ in South Korea
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis

 

Last Updated: 23 Jul 2014

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Regulatory Post-Marketing Surveillance Study for TETRAXIM™
 

Status: Recruiting

Condition Summary: Diphtheria; Tetanus; Pertussis; Poliomyelitis

 

Last Updated: 20 Aug 2014

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Post-marketing Surveillance to Assess the Safety of Infanrix-IPV Vaccine Among Infants and Children in Korea
 

Status: Recruiting

Condition Summary: Acellular Pertussis; Diphtheria; Tetanus; Poliomyelitis

 

Last Updated: 17 Apr 2014

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