Testicular Feminization

Common Name(s)

Testicular Feminization

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Testicular Feminization" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Testicular Feminization" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Testicular Feminization" returned 29 free, full-text research articles on human participants. First 3 results:

Testicular feminization: complete androgen insensitivity syndrome. Discussions based on a case report.
 

Author(s): Constantin Gîngu, Alexandru Dick, Sorin Pătrăşcoiu, Liliana Domnişor, Mihaela Mihai, Mihai Hârza, Ioanel Sinescu

Journal: Rom J Morphol Embryol. 2014 ;55(1):177-81.

 

Testicular feminization is the syndrome when a male, genetically XY, because of various abnormalities of the X chromosome, is resistant to the actions of the androgen hormones, which in turn stops the forming of the male genitalia and gives a female phenotype. The androgen insensitivity ...

Last Updated: 9 Apr 2014

Go To URL
A case of complete testicular feminization: laparoscopic orchiectomy and analysis of androgen receptor gene mutation.
 

Author(s): H Kanayama, T Naroda, Y Inoue, Y Kurokawa, S Kagawa

Journal: Int. J. Urol.. 1999 Jun;6(6):327-30.

 

Analysis of an androgen receptor gene mutation and a bilateral laparoscopic orchiectomy were performed on a 19-year-old patient diagnosed as a case of complete testicular feminization.

Last Updated: 24 Sep 1999

Go To URL
Incomplete testicular feminization syndrome: studies on androgen receptor(AR) function, AR gene analysis, and aromatase activities at puberty and long-term observations of clinical and hormonal features from infancy to puberty.
 

Author(s): K Isurugi, F Hasegawa, N Shibahara, H Mori, H Shima, N Harada, T Hasegawa, S Honma, K Imasaki, H Nawata

Journal: Endocr. J.. 1996 Oct;43(5):557-64.

 

A female infant with partial androgen insensitivity (PAIS) was first seen at 4 months of age with slight virilization of the genitalia and externally palpable testes. Sex chromosome was 46,XY. She received left orchidectomy and exploratory laparotomy at 2 yr of age. At exploratory ...

Last Updated: 1 Apr 1997

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Testicular Feminization" returned 2 free, full-text review articles on human participants. First 3 results:

The role of androgen receptors in the masculinization of brain and behavior: what we've learned from the testicular feminization mutation.
 

Author(s): Damian G Zuloaga, David A Puts, Cynthia L Jordan, S Marc Breedlove

Journal: Horm Behav. 2008 May;53(5):613-26.

 

Many studies demonstrate that exposure to testicular steroids such as testosterone early in life masculinizes the developing brain, leading to permanent changes in behavior. Traditionally, masculinization of the rodent brain is believed to depend on estrogen receptors (ERs) and not ...

Last Updated: 28 Apr 2008

Go To URL
Proceedings: Testicular feminization: studies of the molecular basis of a genetic defect.
 

Author(s): C W Bardin, L P Bullock

Journal: J. Invest. Dermatol.. 1974 Jul;63(1):75-84.

 

Last Updated: 4 Sep 1974

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Pembrolizumab and Enobosarm in Treating Patients With Androgen Receptor Positive Metastatic Triple Negative Breast Cancer
 

Status: Not yet recruiting

Condition Summary: Androgen Receptor Positive; Estrogen Receptor Negative; HER2/Neu Negative; Progesterone Receptor Negative; Recurrent Breast Carcinoma; Stage III Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer; Triple-Negative Breast Carcinoma

 

Last Updated: 21 Nov 2016

Go to URL
Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies
 

Status: Recruiting

Condition Summary: Advanced Epithelial Ovarian; Recurrent Epithelial Ovarian; Fallopian Tube; Primary Peritoneal Carcinoma

 

Last Updated: 24 Oct 2016

Go to URL
A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer
 

Status: Not yet recruiting

Condition Summary: Prostate Cancer

 

Last Updated: 15 Jul 2015

Go to URL