Testicular Feminization

Common Name(s)

Testicular Feminization

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Testicular Feminization" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Testicular Feminization" returned 27 free, full-text research articles on human participants. First 3 results:

Testicular feminization: complete androgen insensitivity syndrome. Discussions based on a case report.
 

Author(s): Constantin Gîngu, Alexandru Dick, Sorin Pătrăşcoiu, Liliana Domnişor, Mihaela Mihai, Mihai Hârza, Ioanel Sinescu

Journal: Rom J Morphol Embryol. 2014 ;55(1):177-81.

 

Testicular feminization is the syndrome when a male, genetically XY, because of various abnormalities of the X chromosome, is resistant to the actions of the androgen hormones, which in turn stops the forming of the male genitalia and gives a female phenotype. The androgen insensitivity ...

Last Updated: 9 Apr 2014

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[Testicular feminization syndrome associated with acute hydramnios: apropos of 1 case].
 

Author(s): M Jemmali, J C Recktenwald

Journal: J Gynecol Obstet Biol Reprod (Paris). 2000 Dec;29(8):797-800.

 

We describe the first, to our knowledge, case of a feminizing testicle associated with acute polyhydramniosis observed at 21 weeks 3 days gestation. There was no fetal malformation or maternal disease that would explain the polyhydramnios. Prenatal diagnosis of feminizing testicle ...

Last Updated: 26 Jan 2001

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Incomplete testicular feminization syndrome: studies on androgen receptor(AR) function, AR gene analysis, and aromatase activities at puberty and long-term observations of clinical and hormonal features from infancy to puberty.
 

Author(s): K Isurugi, F Hasegawa, N Shibahara, H Mori, H Shima, N Harada, T Hasegawa, S Honma, K Imasaki, H Nawata

Journal: Endocr. J.. 1996 Oct;43(5):557-64.

 

A female infant with partial androgen insensitivity (PAIS) was first seen at 4 months of age with slight virilization of the genitalia and externally palpable testes. Sex chromosome was 46,XY. She received left orchidectomy and exploratory laparotomy at 2 yr of age. At exploratory ...

Last Updated: 1 Apr 1997

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Testicular Feminization" returned 1 free, full-text review articles on human participants. First 3 results:

The role of androgen receptors in the masculinization of brain and behavior: what we've learned from the testicular feminization mutation.
 

Author(s): Damian G Zuloaga, David A Puts, Cynthia L Jordan, S Marc Breedlove

Journal: Horm Behav. 2008 May;53(5):613-26.

 

Many studies demonstrate that exposure to testicular steroids such as testosterone early in life masculinizes the developing brain, leading to permanent changes in behavior. Traditionally, masculinization of the rodent brain is believed to depend on estrogen receptors (ERs) and not ...

Last Updated: 28 Apr 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)
 

Status: Recruiting

Condition Summary: Metastatic Breastcancer; Estrogen Receptor Positive Breast Cancer; Estrogen Receptor Negative Neoplasm; Progesterone Receptor Positive Tumor; Progesterone Receptor Negative Neoplasm; Androgen Receptor Gene Overexpression

 

Last Updated: 18 Jun 2015

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MRI in Patients With Kennedy Disease
 

Status: Not yet recruiting

Condition Summary: Bulbo-Spinal Atrophy, X-Linked; Kennedy Disease

 

Last Updated: 15 Jul 2015

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Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors
 

Status: Recruiting

Condition Summary: Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor

 

Last Updated: 24 Jul 2015

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