Temporal arteritis

Common Name(s)

Temporal arteritis, Giant cell arteritis

Giant cell arteritis, also known as temporal arteritis, occurs when one or more arteries become inflamed, swollen and tender. Arteries are the blood vessels that carry oxygen-rich blood from your heart to the rest of your body. Oxygenated blood leaves your heart through your body's main artery, the aorta. The aorta then divides into smaller arteries that deliver blood to all parts of your body, including your brain and internal organs. When these arteries become inflamed or swollen, blood flow decreases and less oxygen can travel to the respective parts of the body.

The exact cause is not known. Researchers believe giant cell arteritis may be an autoimmune disease. Autoimmune diseases occur when our body’s immune or defense system attacks its own healthy cells. Many people with giant cell arteritis often have polymyalgia rheumatica. Older individuals (people older than 50), women, and people of Northern European descent (especially Scandinavian) are more likely to have giant cell arteritis.

Giant cell arteritis can affect any artery, but most commonly affects the arteries that provide blood to the side of the face near the temple. The most common symptoms may include headache, jaw pain, blurred or double vision, fever, weight loss, and pain or stiffness in the neck, shoulder, or hips.

Your doctor can diagnose giant cell arteritis through a combination of a physical exam, blood tests, imaging, and tissue biopsy. Treatment may involve specific medications that help reduce inflammation within the affected arteries. Early diagnosis and treatment are important to avoid complications such as blindness or stroke. If you or a family member has been diagnosed with giant cell arteritis, talk with your doctor or specialist about the most current treatment options. Support groups are also a good resource and can help you connect with others affected by giant cell arteritis.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Temporal arteritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Temporal arteritis" returned 184 free, full-text research articles on human participants. First 3 results:

Temporal arteritis with erythrocyte sedimentation rate <50 mm/h: a clinical reminder.
 

Author(s): Muhammad Raza Cheema, Shakawan M Ismaeel

Journal:

 

Temporal arteritis, also known as giant cell arteritis (GCA), is a systemic vasculitis that predominantly involves the temporal arteries. It is a medical emergency and should be treated promptly as it can lead to permanent loss of vision. It is very commonly associated with a raised ...

Last Updated: 11 Mar 2016

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Hypertrophic Pachymeningitis as a Potential Cause of Headache Associated with Temporal Arteritis.
 

Author(s): Shin-Ichi Tokushige, Hiroyoshi Matsuura, Takuto Hideyama, Koichi Tamura, Risa Maekawa, Yasushi Shiio

Journal: Intern. Med.. 2016 ;55(5):523-6.

 

We herein describe a rare case of temporal arteritis associated with hypertrophic pachymeningitis. An 81-year-old man presented with a right temporal headache that had persisted for one month. A right superficial temporal artery biopsy revealed intimal hypertrophy with increased elastic ...

Last Updated: 3 Mar 2016

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Analysis of Varicella-Zoster Virus in Temporal Arteries Biopsy Positive and Negative for Giant Cell Arteritis.
 

Author(s): Maria A Nagel, Teresa White, Nelly Khmeleva, April Rempel, Philip J Boyer, Jeffrey L Bennett, Andrea Haller, Kelly Lear-Kaul, Balasurbramaniyam Kandasmy, Malena Amato, Edward Wood, Vikram Durairaj, Franz Fogt, Madhura A Tamhankar, Hans E Grossniklaus, Robert J Poppiti, Brian Bockelman, Kathy Keyvani, Lea Pollak, Sonia Mendlovic, Mary Fowkes, Charles G Eberhart, Mathias Buttmann, Klaus V Toyka, Tobias Meyer-ter-Vehn, Vigdis Petursdottir, Don Gilden

Journal: JAMA Neurol. 2015 Nov;72(11):1281-7.

 

Giant cell arteritis (GCA) is the most common systemic vasculitis in elderly individuals. Diagnosis is confirmed by temporal artery (TA) biopsy, although biopsy results are often negative. Despite the use of corticosteroids, disease may progress. Identification of causal agents will ...

Last Updated: 10 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Temporal arteritis" returned 6 free, full-text review articles on human participants. First 3 results:

[Temporal arteritis: treatment controversies].
 

Author(s): J Balsalobre Aznar, J Porta-Etessam

Journal: Neurologia. 2010 Sep;25(7):453-8.

 

Although giant cell or temporal arteritis represents 5-10% of ischaemic optic neuropathies and is the most common arteritis in people over 60 years old. Currently there is no established treatment with oral glucocorticoids available.

Last Updated: 22 Oct 2010

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[Temporal arteritis and cerebrovascular complications].
 

Author(s): Hildegunn Øverlie, Emilia Kerty

Journal: Tidsskr. Nor. Laegeforen.. 2005 Nov;125(21):2936-8.

 

Giant cell (temporal) arteritis is a systemic vasculitis of large and medium sized arteries causing severe visual loss and cerebrovascular accidents. We have treated several patients who developed stroke because of giant-cell arteritis despite high-dose corticosteroid treatment.

Last Updated: 8 Nov 2005

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[Stroke as the first manifestation of temporal arteritis: three case reports and a review of its pathogenesis and treatment].
 

Author(s): A Belenguer-Benavides, C Vilar-Cambies, D Geffner-Sclarsky

Journal: Rev Neurol. ;39(3):227-32.

 

Last Updated: 30 Jul 2004

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Aetiology of TemporaL Arteritis Study
 

Status: Not yet recruiting

Condition Summary: Temporal Arteritis

 

Last Updated: 21 Oct 2015

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Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis
 

Status: Recruiting

Condition Summary: Temporal Arteritis

 

Last Updated: 11 Nov 2016

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Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis
 

Status: Recruiting

Condition Summary: Giant Cell Arteritis

 

Last Updated: 17 Nov 2016

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