Temporal arteritis

Common Name(s)

Temporal arteritis, Giant cell arteritis

Giant cell arteritis, also known as Òtemporal arteritisÓ or ÒHorton's disease,Ó is a form of vasculitis affecting medium and large sized blood vessels, especially those of the aorta and arteries going from the aorta to the arms, legs and the head. Giant cell arteritis most frequently affects the arteries in the head, leading to narrowing and sometimes to complete blockage of the blood vessel. This results in the surrounding tissues being deprived of an adequate blood supply. When giant cell arteritis involves the arteries that supply blood to the eyes, blindness in one or both eyes may develop suddenly. Along with visual changes, the most common symptoms in giant cell arteritis include headaches, pain in the jaw or tongue muscles when eating or talking, tenderness of the scalp, fevers, and arthritis, particularly pain and stiffness of the shoulders and hips. This pain and stiffness of the shoulders and hips is called polymyalgia rheumatica. Polymyalgia rheumatica can occur without giant cell arteritis.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Temporal arteritis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Temporal arteritis" returned 145 free, full-text research articles on human participants. First 3 results:

Biopsy of the temporal artery in a patient with giant cell arteritis.
 

Author(s): Megumi Toko, Hiroshi Oiwa, Shoji Mihara, Eiji Sugiyama

Journal: Intern. Med.. 2013 ;52(18):2165.

 

Last Updated: 17 Sep 2013

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Association between histological features in temporal artery biopsies and clinical features of patients with giant cell arteritis.
 

Author(s): Gabriel S Breuer, Ronit Nesher, Konstantin Reinus, Gideon Nesher

Journal: Isr. Med. Assoc. J.. 2013 Jun;15(6):271-4.

 

In most cases of giant cell arteritis (GCA) the diagnosis is confirmed by temporal artery biopsy. Aside from the diagnostic purpose, histological parameters may serve as prognostic markers.

Last Updated: 25 Jul 2013

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Multifocal VZV vasculopathy with temporal artery infection mimics giant cell arteritis.
 

Author(s): Maria A Nagel, Jeffrey L Bennett, Nelly Khmeleva, Alexander Choe, April Rempel, Philip J Boyer, Don Gilden

Journal: Neurology. 2013 May;80(22):2017-21.

 

To address the incidence of varicella-zoster virus (VZV) infection in patients with biopsy-negative giant cell arteritis (GCA), we examined archived biopsy-negative temporal arteries from subjects with clinically suspected GCA for the presence of VZV antigen.

Last Updated: 28 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Temporal arteritis" returned 6 free, full-text review articles on human participants. First 3 results:

[Temporal arteritis: treatment controversies].
 

Author(s): J Balsalobre Aznar, J Porta-Etessam

Journal: Neurologia. 2010 Sep;25(7):453-8.

 

Although giant cell or temporal arteritis represents 5-10% of ischaemic optic neuropathies and is the most common arteritis in people over 60 years old. Currently there is no established treatment with oral glucocorticoids available.

Last Updated: 22 Oct 2010

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[Temporal arteritis and cerebrovascular complications].
 

Author(s): Hildegunn Øverlie, Emilia Kerty

Journal: Tidsskr. Nor. Laegeforen.. 2005 Nov;125(21):2936-8.

 

Giant cell (temporal) arteritis is a systemic vasculitis of large and medium sized arteries causing severe visual loss and cerebrovascular accidents. We have treated several patients who developed stroke because of giant-cell arteritis despite high-dose corticosteroid treatment.

Last Updated: 8 Nov 2005

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[Stroke as the first manifestation of temporal arteritis: three case reports and a review of its pathogenesis and treatment].
 

Author(s): A Belenguer-Benavides, C Vilar-Cambies, D Geffner-Sclarsky

Journal: Rev Neurol. ;39(3):227-32.

 

Last Updated: 30 Jul 2004

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Study of Temporal Arteritis
 

Status: Not yet recruiting

Condition Summary: Temporal Arteritis

 

Last Updated: 25 May 2010

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Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis
 

Status: Recruiting

Condition Summary: Temporal Arteritis

 

Last Updated: 22 Nov 2013

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Sensitivity and Specificity of Color Doppler Directed Temporal Artery Biopsy as Compared to Standard Random Biopsy in the Diagnosis of Temporal Arteritis
 

Status: Recruiting

Condition Summary: Temporal Arteritis; Duplex of Temporal Artery; Biopsy of Temporal Artery

 

Last Updated: 5 Dec 2006

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