Tardive dyskinesia

Common Name(s)

Tardive dyskinesia, Oral facial dyskinesia

Tardive dyskinesia is a neurological movement disorder that is caused by the long-term use of a certain type of medications called neuroleptics. Neuroleptic drugs are usually prescribed for psychiatric conditions, although they may be used to treat gastrointestinal or neurological conditions in some cases. Tardive dyskinesia is primarily characterized by repetitive involuntary movements of the jaw, lips and tongue such as grimacing; sticking out the tongue; and smacking, puckering and pursing the lips. Some affected people may also experience involuntary rapid, jerking movements (chorea) or slow, writhing movements (athetosis) of the arms and/or legs. It is unclear why some people who take neuroleptic medications develop these symptoms while others do not. Treatment for this condition varies but may include stopping or minimizing the use of neuroleptic drugs and/or taking additional medications to to reduce the severity of the symptoms
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tardive dyskinesia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tardive dyskinesia" returned 110 free, full-text research articles on human participants. First 3 results:

Randomized controlled trial of deutetrabenazine for tardive dyskinesia: The ARM-TD study.
 

Author(s): Hubert H Fernandez, Stewart A Factor, Robert A Hauser, Joohi Jimenez-Shahed, William G Ondo, L Fredrik Jarskog, Herbert Y Meltzer, Scott W Woods, Danny Bega, Mark S LeDoux, David R Shprecher, Charles Davis, Mat D Davis, David Stamler, Karen E Anderson

Journal: Neurology. 2017 May;88(21):2003-2010.

 

To determine the efficacy and safety of deutetrabenazine as a treatment for tardive dyskinesia (TD).

Last Updated: 31 Dec 1969

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Co-morbid obsessive compulsive and hypochondriac disorders complicated by tardive dyskinesia in a Nigerian man.
 

Author(s): N C Aghukwa

Journal: Niger J Clin Pract. ;19(1):145-9.

 

The objective was to report a case of obsessive-compulsive disorder (OCD) with comorbid somatic symptoms that was complicated by movement disorders. A literature search on related issues was done online with Google Scholar, followed by a chronological report of the index case. This ...

Last Updated: 31 Dec 1969

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Tardive dyskinesia occurring in a young woman after withdrawal of an atypical antipsychotic drug.
 

Author(s): Mohammed A Alblowi, Fahad D Alosaimi

Journal: Neurosciences (Riyadh). 2015 Oct;20(4):376-9.

 

Tardive dyskinesia (TD) is one of the most serious and disturbing side-effects of dopamine receptor antagonists. It affects 20-50% of patients on long-term antipsychotic therapy. The pathophysiology of TD remains poorly understood, and treatment is often challenging. Here, we present ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tardive dyskinesia" returned 23 free, full-text review articles on human participants. First 3 results:

Epidemiology, Prevention, and Assessment of Tardive Dyskinesia and Advances in Treatment.
 

Author(s): Christoph U Correll, John M Kane, Leslie L Citrome

Journal: J Clin Psychiatry. ;78(8):1136-1147.

 

​​ Tardive dyskinesia (TD) is a disorder characterized by involuntary movements, typically of the orofacial muscles and also of the extremities and other muscle groups. The condition is associated with exposure to dopamine receptor blocking agents, including antipsychotics. Because ...

Last Updated: 31 Dec 1969

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Tardive dyskinesia (syndrome): Current concept and modern approaches to its management.
 

Author(s): Paul P Lerner, Chanoch Miodownik, Vladimir Lerner

Journal: Psychiatry Clin. Neurosci.. 2015 Jun;69(6):321-34.

 

Tardive dyskinesia is a serious, disabling and potentially permanent, neurological hyperkinetic movement disorder that occurs after months or years of taking psychotropic drugs. The pathophysiology of tardive dyskinesia is complex, multifactorial and still not fully understood. A ...

Last Updated: 31 Dec 1969

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New and emerging treatments for symptomatic tardive dyskinesia.
 

Author(s): Abdul Qayyum Rana, Zishan M Chaudry, Pierre J Blanchet

Journal:

 

The aim of this review is to assess new, emerging, and experimental treatment options for tardive dyskinesia (TD). The methods to obtain relevant studies for review included a MEDLINE search and a review of studies in English, along with checking reference lists of articles. The leading ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Repetitive Transcranial Magnetic Stimulation for the Treatment of the Tardive Dyskinesia.
 

Status: Recruiting

Condition Summary: Tardive Dyskinesia

 

Last Updated: 11 Jun 2017

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Safety and Efficacy of Propranolol in the Treatment of Tardive Dyskinesia
 

Status: Recruiting

Condition Summary: Tardive Dyskinesia

 

Last Updated: 21 Sep 2017

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Efficacy and Safety of MT-5199 in Subjects With Tardive Dyskinesia
 

Status: Recruiting

Condition Summary: Tardive Dyskinesia

 

Last Updated: 8 Aug 2017

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