Tardive dyskinesia

Common Name(s)

Tardive dyskinesia, Oral facial dyskinesia

Tardive dyskinesia is a neurological movement disorder that is caused by the long-term use of a certain type of medications called neuroleptics. Neuroleptic drugs are usually prescribed for psychiatric conditions, although they may be used to treat gastrointestinal or neurological conditions in some cases. Tardive dyskinesia is primarily characterized by repetitive involuntary movements of the jaw, lips and tongue such as grimacing; sticking out the tongue; and smacking, puckering and pursing the lips. Some affected people may also experience involuntary rapid, jerking movements (chorea) or slow, writhing movements (athetosis) of the arms and/or legs. It is unclear why some people who take neuroleptic medications develop these symptoms while others do not. Treatment for this condition varies but may include stopping or minimizing the use of neuroleptic drugs and/or taking additional medications to to reduce the severity of the symptoms
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tardive dyskinesia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tardive dyskinesia" returned 109 free, full-text research articles on human participants. First 3 results:

Efficacy of aripiprazole in antidepressants-induced tardive dystonia and tardive dyskinesia: a case report.
 

Author(s): Lyang Huh, Bong Ju Lee

Journal: Psychiatr Danub. 2015 Jun;27(2):195-7.

 

Last Updated: 10 Jun 2015

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[Tardive dyskinesia in patients with schizophrenia treated with olanzapine - results from a 20-month, prospective, open study under naturalistic conditions].
 

Author(s): Tomasz Szafrański

Journal: Psychiatr. Pol.. ;48(6):1155-65.

 

The objective of the study was to assess the prevalence and incidence of tardive dyskinesia in patients treated with olanzapine during the follow-up period of 20 months.

Last Updated: 26 Feb 2015

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Tardive dyskinesia in relation to estimated dopamine D2 receptor occupancy in patients with schizophrenia: analysis of the CATIE data.
 

Author(s): Kazunari Yoshida, Robert R Bies, Takefumi Suzuki, Gary Remington, Bruce G Pollock, Yuya Mizuno, Masaru Mimura, Hiroyuki Uchida

Journal: Schizophr. Res.. 2014 Mar;153(1-3):184-8.

 

The objective of this study was to evaluate the relationship between antipsychotic-induced tardive dyskinesia (TD) and estimated dopamine D2 receptor occupancy levels in patients with schizophrenia, using the dataset from the Clinical Antipsychotic Trials in Intervention Effectiveness (CATIE).

Last Updated: 17 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tardive dyskinesia" returned 12 free, full-text review articles on human participants. First 3 results:

New and emerging treatments for symptomatic tardive dyskinesia.
 

Author(s): Abdul Qayyum Rana, Zishan M Chaudry, Pierre J Blanchet

Journal:

 

The aim of this review is to assess new, emerging, and experimental treatment options for tardive dyskinesia (TD). The methods to obtain relevant studies for review included a MEDLINE search and a review of studies in English, along with checking reference lists of articles. The leading ...

Last Updated: 15 Nov 2013

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Globus pallidus interna deep brain stimulation for tardive dyskinesia: case report and review of the literature.
 

Author(s): Meredith A Spindler, Nicholas B Galifianakis, Jayne R Wilkinson, John E Duda

Journal: Parkinsonism Relat. Disord.. 2013 Feb;19(2):141-7.

 

Tardive dyskinesia (TD) can be a disabling condition and is frequently refractory to medical therapy. Over the past decade there have been many reports of TD patients experiencing significant benefit with deep brain stimulation (DBS) of the globus pallidus interna (GPi). The growing ...

Last Updated: 12 Feb 2013

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Relevance of animal models to human tardive dyskinesia.
 

Author(s): Pierre J Blanchet, Marie-Thérèse Parent, Pierre H Rompré, Daniel Lévesque

Journal:

 

Tardive dyskinesia remains an elusive and significant clinical entity that can possibly be understood via experimentation with animal models. We conducted a literature review on tardive dyskinesia modeling. Subchronic antipsychotic drug exposure is a standard approach to model tardive ...

Last Updated: 30 Apr 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Deep Brain Stimulation for Patients With Tardive Dyskinesia and or Dystonia
 

Status: Recruiting

Condition Summary: Tardive Dyskinesia; Tardive Dystonia

 

Last Updated: 13 Aug 2015

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Efficacy of Docosahexaenoic Acid on Tardive Dyskinesia
 

Status: Recruiting

Condition Summary: Tardive Dyskinesia

 

Last Updated: 21 Feb 2008

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D-Serine Treatment For Tardive Dyskinesia
 

Status: Recruiting

Condition Summary: Schizophrenia and Schizoaffective Disorder; Tardive Dyskinesia

 

Last Updated: 23 Aug 2015

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