Takayasu arteritis

Common Name(s)

Takayasu arteritis, Aortic arch syndrome, Takayasu's arteritis, TAK, Pulseless disease

Takayasu’s arteritis is a rare form of blood vessel inflammation (vasculitis) that typically affects the large artery that carries blood from your heart to the rest of your body (the aorta), as well as the artery that carries blood from the heart to the lungs (pulmonary artery). Signs and symptoms of Takayasu’s arteritis often occur in two stages. The first stage (systemic stage) may include symptoms such general fatigue, fever, headache, fast and unintentional weight loss, joint pain and sore muscles. The second stage (occlusive stage) develops when inflammation causes the affected arteries to narrow. This narrowing can cause a decrease in blood flow along with a decrease in the amount of oxygen and nutrients that can reach tissues and organs. Symptoms of the second stage can include dizziness, visual problems, shortness of breath, chest or abdominal pain, weakness, change in limb color, fainting, stroke, seizure, or high blood pressure. Symptoms depend on which arteries are inflamed.

The exact cause of Takayasu’s arteritis is not known. The inflamed arteries are believed to be caused by an autoimmune disease, which means the body’s immune cells attack the tissue in the arteries, mistaking it for something foreign (from outside the body). To diagnose the condition, a doctor will collect a medical history, conduct a physical exam, perform blood tests and collect images of the heart, chest and arteries. In some cases, Takayasu’s arteritis can be managed by medication. However, if it becomes severe enough, surgery may be necessary. If you are diagnosed with Takayasu’s arteritis, talk with your doctor to discuss the right treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Takayasu arteritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Takayasu arteritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Takayasu arteritis" returned 176 free, full-text research articles on human participants. First 3 results:

Inflammation Is Associated With Platelet Coagulation Function Rather Than Enzymatic Coagulation Function in Patients With Takayasu Arteritis.
 

Author(s): Xiao Wang, Aimin Dang, Naqiang Lv, Nan Cheng, Xuesen Cheng

Journal: Int Heart J. 2017 Aug;58(4):589-592.

 

The integral changes of coagulation and fibrinolysis, and their relationships with inflammation in patients with Takayasu arteritis (TA) remain undetermined. The purpose of this study was to analyze the changes of coagulation and fibrinolysis process in patients with TA by thrombelastography ...

Last Updated: 13 Jul 2017

Go To URL
An unrecognised presentation of Takayasu arteritis: superficial femoral artery involvement.
 

Author(s): Hui Dong, Wuqiang Che, Xiongjing Jiang, Meng Peng, Yubao Zou, Huimin Zhang, Bo Xu, Yuejin Yang, Runlin Gao

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 103(1):83-87.

 

Superficial femoral artery (SFA) involvement in Takayasu arteritis (TAK) has rarely been reported. The purpose of this study was to investigate the clinical characteristic and clinical outcomes of endovascular therapy in such patients.

Last Updated: 2 Dec 2016

Go To URL
Association of FCGR2A/FCGR3A variant rs2099684 with Takayasu arteritis in the Han Chinese population.
 

Author(s): Si Chen, Xiaoting Wen, Jing Li, Yuan Li, Liubing Li, Xinping Tian, Hui Yuan, Fengchun Zhang, Yongzhe Li

Journal: Oncotarget. 2017 Mar;8(10):17239-17245.

 

Takayasu arteritis (TA) is a chronic large-vessel vasculitis of unclear pathogenesis. A recent genome-wide association study (GWAS) has revealed that the FCGR2A/FCGR3A, EEFSEC, RPS9/LILRB3, RIPPLY2 and MLX genes confer susceptibility to TA. We investigated the linkage between presumptive ...

Last Updated: 21 Oct 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Takayasu arteritis" returned 11 free, full-text review articles on human participants. First 3 results:

Endovascular balloon angioplasty versus stenting in patients with Takayasu arteritis: A meta-analysis.
 

Author(s): Han Saem Jeong, Jae Hyun Jung, Gwan Gyu Song, Sung Jae Choi, Soon Jun Hong

Journal: Medicine (Baltimore). 2017 Jul;96(29):e7558.

 

Symptomatic or significant vascular lesions of Takayasu arteritis (TA) need interventions. Although percutaneous transluminal angioplasty with balloon is a less invasive and safe method, stent implantation in TA can be an alternative option. However, superiority between balloon angioplasty ...

Last Updated: 20 Jul 2017

Go To URL
Aortic rupture during aortoplasty in Takayasu arteritis--a rare complication: case report and review of literature.
 

Author(s): Vimal Mehta, Bhagya Narayan Pandit, Jamal Yusuf, Saibal Mukhopadhyay, Jagdeep Yadav, Vijay Trehan, Sanjay Tyagi

Journal: Indian Heart J. ;66(3):350-4.

 

Balloon angioplasty of the stenosed aorta is usually a relatively simple, yet potentially a catastrophic procedure. Aortic rupture during aortoplasty, though uncommon, carries a high mortality. We report case of a 39-year-old female with aortoarteritis with multiple arterial stenoses ...

Last Updated: 30 Jun 2014

Go To URL
Takayasu arteritis as a cause of arterial hypertension. Case report and literature review.
 

Author(s): Elżbieta Sadurska, Renata Jawniak, Marek Majewski, Elżbieta Czekajska-Chehab

Journal: Eur. J. Pediatr.. 2012 May;171(5):863-9.

 

We report a 16-year-old girl in whom Takayasu arteritis (TA) was manifested mainly by severe arterial hypertension on her right arm, which was detected during a routine examination at school. Her systolic blood pressure on the right arm was significantly higher than that on the left ...

Last Updated: 1 Jun 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

China Takayasu Arteritis Registry (CTA Registry)
 

Status: Recruiting

Condition Summary: TAKAYASU ARTERITIS

 

Last Updated: 13 Nov 2016

Go to URL
Registration Study of Takayasu's Arteritis in China
 

Status: Not yet recruiting

Condition Summary: Takayasu Arteritis

 

Last Updated: 23 Jun 2017

Go to URL
Takayasu Arteritis Clinical Trial in China
 

Status: Recruiting

Condition Summary: Takayasu Arteritis

 

Last Updated: 9 Sep 2017

Go to URL