Takayasu arteritis

Common Name(s)

Takayasu arteritis, Takayasu's arteritis, TAK, Pulseless disease, Aortic arch syndrome

Takayasu’s arteritis is a rare form of blood vessel inflammation (vasculitis) that typically affects the large artery that carries blood from your heart to the rest of your body (the aorta), as well as the artery that carries blood from the heart to the lungs (pulmonary artery). Signs and symptoms of Takayasu’s arteritis often occur in two stages. The first stage (systemic stage) may include symptoms such general fatigue, fever, headache, fast and unintentional weight loss, joint pain and sore muscles. The second stage (occlusive stage) develops when inflammation causes the affected arteries to narrow. This narrowing can cause a decrease in blood flow along with a decrease in the amount of oxygen and nutrients that can reach tissues and organs. Symptoms of the second stage can include dizziness, visual problems, shortness of breath, chest or abdominal pain, weakness, change in limb color, fainting, stroke, seizure, or high blood pressure. Symptoms depend on which arteries are inflamed.

The exact cause of Takayasu’s arteritis is not known. The inflamed arteries are believed to be caused by an autoimmune disease, which means the body’s immune cells attack the tissue in the arteries, mistaking it for something foreign (from outside the body). To diagnose the condition, a doctor will collect a medical history, conduct a physical exam, perform blood tests and collect images of the heart, chest and arteries. In some cases, Takayasu’s arteritis can be managed by medication. However, if it becomes severe enough, surgery may be necessary. If you are diagnosed with Takayasu’s arteritis, talk with your doctor to discuss the right treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Takayasu arteritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Takayasu arteritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Takayasu arteritis" returned 160 free, full-text research articles on human participants. First 3 results:

[Chronic periodontitis with Takayasu arteritis: a case report].
 

Author(s): Wei Gao, Qing-xian Luan

Journal: Beijing Da Xue Xue Bao. 2015 Oct;47(5):875-7.

 

This case report concerns a 23-year-old woman with chronic periodontitis who had been previously diagnosed with Takayasu arteritis (TA). Her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level were decreased before and 3 months after non-surgical periodontal therapy ...

Last Updated: 17 Oct 2015

Go To URL
Takayasu arteritis and ulcerative cutaneous sarcoidosis.
 

Author(s): Gangji Ri, Emi Yoshikawa, Tarou Shigekiyo, Rui Ishii, Yusuke Okamoto, Ken Kakita, Toshihiro Otsuka, Hideaki Morita, Motomu Tsuji, Shinichi Moriwaki, Masahiro Daimon, Takahiro Katsumata, Koichi Sohmiya, Masaaki Hoshiga, Nobukazu Ishizaka

Journal: Intern. Med.. 2015 ;54(9):1075-80.

 

A 67-year-old woman was referred to our hospital due to a refractory lower extremity ulcer. Occlusion of the bilateral superficial femoral arteries and a difference (>50 mmHg) in blood pressure between the bilateral upper limbs were noted. In addition to occlusion of the left subclavian ...

Last Updated: 7 May 2015

Go To URL
Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom.
 

Author(s): Despina Eleftheriou, Giulia Varnier, Pavla Dolezalova, Anne-Marie McMahon, Muthana Al-Obaidi, Paul A Brogan

Journal:

 

Takayasu arteritis (TA) is an idiopathic large-vessel vasculitis affecting the aorta and its major branches. Although the disease rarely affects children, it does occur, even in infants. The objective of this study was to evaluate the clinical features, disease activity, treatment ...

Last Updated: 17 Apr 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Takayasu arteritis" returned 13 free, full-text review articles on human participants. First 3 results:

Aortic rupture during aortoplasty in Takayasu arteritis--a rare complication: case report and review of literature.
 

Author(s): Vimal Mehta, Bhagya Narayan Pandit, Jamal Yusuf, Saibal Mukhopadhyay, Jagdeep Yadav, Vijay Trehan, Sanjay Tyagi

Journal: Indian Heart J. ;66(3):350-4.

 

Balloon angioplasty of the stenosed aorta is usually a relatively simple, yet potentially a catastrophic procedure. Aortic rupture during aortoplasty, though uncommon, carries a high mortality. We report case of a 39-year-old female with aortoarteritis with multiple arterial stenoses ...

Last Updated: 30 Jun 2014

Go To URL
Takayasu arteritis in a 4-year-old girl: case report and brief overview of the pediatric literature.
 

Author(s): Ebru Aypar, Ash Celebi-Tayfur, Melike Keser, Dursun Odabaş, Fatih Ozaltin, Yahya Paksoy, Seza Ozen

Journal: Turk. J. Pediatr.. ;54(5):536-9.

 

Takayasu arteritis (TA) is a large vessel vasculitis that involves the aorta, its major branches and pulmonary arteries. Diagnosis of TA during childhood remains challenging due to the non-specific symptoms. We report a four-year-old girl presenting with fever, fatigue, weight loss, ...

Last Updated: 22 Feb 2013

Go To URL
Takayasu arteritis as a cause of arterial hypertension. Case report and literature review.
 

Author(s): Elżbieta Sadurska, Renata Jawniak, Marek Majewski, Elżbieta Czekajska-Chehab

Journal: Eur. J. Pediatr.. 2012 May;171(5):863-9.

 

We report a 16-year-old girl in whom Takayasu arteritis (TA) was manifested mainly by severe arterial hypertension on her right arm, which was detected during a routine examination at school. Her systolic blood pressure on the right arm was significantly higher than that on the left ...

Last Updated: 1 Jun 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy and Tolerance of Tocilizumab In Takayasu Arteritis
 

Status: Not yet recruiting

Condition Summary: TAKAYASU ARTERITIS

 

Last Updated: 27 Mar 2014

Go to URL
Determining Disease Activity Biomarkers in Individuals With Takayasu's Arteritis
 

Status: Recruiting

Condition Summary: Takayasu's Arteritis

 

Last Updated: 4 Sep 2015

Go to URL
Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu Arteritis
 

Status: Recruiting

Condition Summary: Takayasu's Arteritis

 

Last Updated: 26 May 2015

Go to URL