T cell immunodeficiency primary

Common Name(s)

T cell immunodeficiency primary

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "T cell immunodeficiency primary" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "T cell immunodeficiency primary" returned 46 free, full-text research articles on human participants. First 3 results:

Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection.
 

Author(s): Heather A Prentice, Hailin Lu, Matthew A Price, Anatoli Kamali, Etienne Karita, Shabir Lakhi, Eduard J Sanders, Omu Anzala, Susan Allen, Paul A Goepfert, Eric Hunter, Jill Gilmour, Jianming Tang

Journal:

 

In individuals with HIV-1 infection, depletion of CD4(+) T cells is often accompanied by a malfunction of CD8(+) T cells that are persistently activated and/or exhausted. While the dynamics and correlates of CD4 counts have been well documented, the same does not apply to CD8 counts. ...

Last Updated: 15 Sep 2016

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T-cell activation discriminates subclasses of symptomatic primary humoral immunodeficiency diseases in adults.
 

Author(s): Marie-Quitterie Picat, Rodolphe Thiébaut, François Lifermann, Xavier Delbrel, Daniel Adoue, Linda Wittkop, Anne-Laure Fauchais, Patrick Rispal, Jean-François Moreau, Jean-François Viallard

Journal:

 

Symptomatic Primary Humoral Immunodeficiency Diseases (PHID) constitute a highly heterogeneous group of diseases characterized by a shared hypogammaglobulinemia, resulting in increased risk of recurrent or severe infections. Associations have been described with a variety of immunological ...

Last Updated: 25 Mar 2014

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α- and β-papillomavirus infection in a young patient with an unclassified primary T-cell immunodeficiency and multiple mucosal and cutaneous lesions.
 

Author(s): Manuela M Landini, Cinzia Borgogna, Alberto Peretti, Enrico Colombo, Elisa Zavattaro, Renzo Boldorini, Umberto Miglio, John Doorbar, Paolo Ravanini, Rajesh Kumar, Daniele Moratto, Raffaele Badolato, Marco De Andrea, Marisa Gariglio

Journal: J. Am. Acad. Dermatol.. 2014 Jul;71(1):108-15.e1.

 

Correlating human papillomavirus (HPV) type with the clinical and histopathological features of skin lesions (from genital and nongenital sites) can present a diagnostic challenge.

Last Updated: 20 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "T cell immunodeficiency primary" returned 2 free, full-text review articles on human participants. First 3 results:

Loss of MAGT1 abrogates the Mg2+ flux required for T cell signaling and leads to a novel human primary immunodeficiency.
 

Author(s): Feng-Yen Li, Michael J Lenardo, Benjamin Chaigne-Delalande

Journal: Magnes Res. 2011 Sep;24(3):S109-14.

 

Although Mg(2+) has a well-recognized role as an essential cofactor for all ATP-binding enzymes, its role as a signaling ion, like Ca(2+), has been controversial. A requirement for Mg(2+)for optimal T lymphocyte stimulation was demonstrated more than 30 years ago, but the mechanism ...

Last Updated: 19 Oct 2011

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Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency--lessons learned from monogenic disorders in mice and men.
 

Author(s): Lisa S Westerberg, Christoph Klein, Scott B Snapper

Journal: Curr. Opin. Immunol.. 2008 Dec;20(6):646-54.

 

A key feature of the immune system is the capacity to monitor and control infections from non-self pathogens while maintaining tolerance to self-antigens. Primary immunodeficiencies (PID) are characterized by an increased susceptibility to infections, often associated with aberrant ...

Last Updated: 28 Nov 2008

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pilot Trial of Allogeneic Blood or Marrow Transplanation for Primary Immunodeficiencies
 

Status: Recruiting

Condition Summary: Primary T-cell Immunodeficiency Disorders; Common Variable Immunodeficiency; Immune System Diseases; Autoimmune Lymphoproliferative; Lymphoproliferative Disorders

 

Last Updated: 12 May 2017

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Multivirus-specific Cytotoxic T Lymphocytes (mCTL)
 

Status: Recruiting

Condition Summary: Refractory Viral Infections

 

Last Updated: 19 Oct 2016

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Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases
 

Status: Recruiting

Condition Summary: Primary Immune Deficiency Disorders; Hemophagocytic Lymphohistiocytosis; Inherited Bone Marrow Failure Syndrome; Hemoglobinopathies; Metabolic Disorders

 

Last Updated: 31 Mar 2017

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