Syringomyelia

Common Name(s)

Syringomyelia

Syringomyelia is a disorder in which a cyst, called a syrinx, forms within the spinal cord. This cyst expands and elongates over time, destroying the center of the spinal cord which can result in pain, weakness, stiffness in the back, shoulders, arms, or legs, headaches, and insensitivity to temperature (especially in the hands). Symptoms vary from person to person. Syringomyelia is often related to a congenital abnormality of the brain called a Chiari I malformation, but may also occur as a complication of trauma, meningitis, hemorrhage, a tumor, or arachnoiditis. Symptoms may appear months or even years after the initial injury. Some cases of syringomyelia are familial, although this is rare. Treatment often involves surgery and avoiding activities that involve straining. Drainage of the cysts using a catheter, drainage tubes, and valves may be required in some patients. If not treated, the disorder can lead to progressive weakness in the arms and legs, loss of hand sensation, and chronic, severe pain.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Syringomyelia" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Syringomyelia" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

http://www.asap.org

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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General Resources

Vimeo Resource

Related Disorders Lecture Series

Updated 7 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Syringomyelia" returned 195 free, full-text research articles on human participants. First 3 results:

Relationship of syrinx size and tonsillar descent to spinal deformity in Chiari malformation Type I with associated syringomyelia.
 

Author(s): Jakub Godzik, Michael P Kelly, Alireza Radmanesh, David Kim, Terrence F Holekamp, Matthew D Smyth, Lawrence G Lenke, Joshua S Shimony, Tae Sung Park, Jeffrey Leonard, David D Limbrick

Journal: J Neurosurg Pediatr. 2014 Apr;13(4):368-74.

 

Chiari malformation Type I (CM-I) is a developmental abnormality often associated with a spinal syrinx. Patients with syringomyelia are known to have an increased risk of scoliosis, yet the influence of specific radiographically demonstrated features on the prevalence of scoliosis ...

Last Updated: 1 Apr 2014

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[Recurrent cold injuries of right hand as the first presentation of syringomyelia: a case report].
 

Author(s): Yin-Bo Chen, Xiao-Sheng Hao, Bo Zhang, Yun-Peng Hao, Dong Liang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 Jan;16(1):91.

 

Last Updated: 27 Jan 2014

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[Adhesive arachnoiditis and dorsal syringomyelia secondary to subarachnoid haemorrhage].
 

Author(s): Rafael Galiano, Arantxa Navarré-Gimeno, Vicente Miranda-Gonzalbo, Miguel García--Escrig, Iratxe Jiménez, Luis Aznar

Journal: Rev Neurol. 2013 Jun;56(12):639-40.

 

Last Updated: 7 Jun 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Syringomyelia" returned 12 free, full-text review articles on human participants. First 3 results:

Syringomyelia and arachnoid cysts associated with spinal arachnoiditis following subarachnoid hemorrhage.
 

Author(s): Shunsuke Ishizaka, Kentaro Hayashi, Munehiro Otsuka, Shuji Fukuda, Keishi Tsunoda, Ryujiro Ushijima, Naoki Kitagawa, Kazuhiko Suyama, Izumi Nagata

Journal: Neurol. Med. Chir. (Tokyo). 2012 ;52(9):686-90.

 

A 66-year-old woman with primary Sjogren syndrome developed syringomyelia following two episodes of subarachnoid hemorrhage (SAH) due to the rupture of basilar artery aneurysms. Gait disturbance and abnormal sensation with pain over the foot and abdomen appeared 3 years after the ...

Last Updated: 25 Sep 2012

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Foramen magnum arachnoid cyst induces compression of the spinal cord and syringomyelia: case report and literature review.
 

Author(s): Haiyan Huang, Yuanqian Li, Kan Xu, Ye Li, Limei Qu, Jinlu Yu

Journal: Int J Med Sci. 2011 ;8(4):345-50.

 

It is very rare that a foramen magnum arachnoid cyst induces compression of the spinal cord and syringomyelia, and currently there are few treatment experiences available. Here we reported the case of a 43-year-old male patient who admitted to the hospital due to weakness and numbness ...

Last Updated: 7 Jun 2011

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Malformations of the craniocervical junction (Chiari type I and syringomyelia: classification, diagnosis and treatment).
 

Author(s): Alfredo Avellaneda Fernández, Alberto Isla Guerrero, Maravillas Izquierdo Martínez, María Eugenia Amado Vázquez, Javier Barrón Fernández, Ester Chesa i Octavio, Javier De la Cruz Labrado, Mercedes Escribano Silva, Marta Fernández de Gamboa Fernández de Araoz, Rocío García-Ramos, Miguel García Ribes, Carmen Gómez, Joaquín Insausti Valdivia, Ramón Navarro Valbuena, José R Ramón

Journal:

 

Chiari disease (or malformation) is in general a congenital condition characterized by an anatomic defect of the base of the skull, in which the cerebellum and brain stem herniate through the foramen magnum into the cervical spinal canal. The onset of Chiari syndrome symptoms usually ...

Last Updated: 18 Dec 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Prospective Natural History Study of Patients With Syringomyelia
 

Status: Recruiting

Condition Summary: Syringomyelia; Arnold Chiari Deformity

 

Last Updated: 14 Mar 2014

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Genetic Analysis of the Chiari I Malformation
 

Status: Recruiting

Condition Summary: Syringomyelia; Type I Arnold Chiari Malformation

 

Last Updated: 14 Mar 2014

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The Genetics of Chiari Type I Malformation
 

Status: Recruiting

Condition Summary: Chiari Type I Malformation

 

Last Updated: 11 Sep 2014

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