Synovial Chondromatosis

Common Name(s)

Synovial Chondromatosis

Synovial chondromatosis is a type of non-cancerous tumor that arises in the lining of a joint. The knee is most commonly affected, however it can affect any joint. The tumors begin as small nodules of cartilage. These nodules can separate and become loose within the joint. Some tumors may be no larger than a grain of rice.  Synovial chondromatosis most commonly occurs in adults ages 20 to 50. Signs and symptoms may include pain, swelling, a decreased range of motion, and locking of the joint. The cause of the condition is unknown. Treatment may involve surgery to remove the tumor. Recurrences are common.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Synovial Chondromatosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Synovial Chondromatosis" returned 50 free, full-text research articles on human participants. First 3 results:

A neglected case of giant synovial chondromatosis in knee joint.
 

Author(s): Sancar Serbest, Ugur Tiftikçi, Fatih Karaaslan, Haci Bayram Tosun, Hüseyin Fatih Sevinç, Mahi Balci

Journal:

 

Synovial chondromatosis is a rare benign condition arising from the synovial membrane of the joints, synovial sheaths or bursae around the joints. Primary synovial chondromatosis typically affects the large joints in the third to fifth decade of life. The purpose of this case report ...

Last Updated: 25 Nov 2015

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Uncalcified Synovial Chondromatosis in the Pisotriquetral Joint.
 

Author(s): Hyo-Kon Kim, Sung-Han Ha, Gi-Jun Lee, Sun-O Yu, Jung-Rae Kim

Journal: Clin Orthop Surg. 2015 Sep;7(3):414-7.

 

Synovial chondromatosis is a rare lesion in the wrist, but some cases in the distal radioulnar joint have been reported and previous case reports emphasize joint calcifications, shown on preoperative plain radiographs. We report an extremely uncommon case of synovial chondromatosis ...

Last Updated: 2 Sep 2015

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Transforming growth factor beta 3 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint.
 

Author(s): Yingjie Li, Loaye Abdelaziz El Mozen, Hengxing Cai, Wei Fang, Qinggong Meng, Jian Li, Mohong Deng, Xing Long

Journal:

 

Synovial chondromatosis (SC) of temporomandibular joint is rare proliferative disorder featured by the formation of cartilaginous nodules in synovium and joint space. Transforming growth factor beta 3 (TGF-β3) is closely related to chondrogenic differentiation, and might participate ...

Last Updated: 6 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Synovial Chondromatosis" returned 3 free, full-text review articles on human participants. First 3 results:

Synovial chondromatosis of the temporomandibular joint.
 

Author(s): Juan Francisco Reyes Macías, Martín Sánchez Prieto

Journal:

 

Synovial Chondromatosis (SC) is a disease whose etiology is unknown, can be defined as a benign synovial process characterized by the formation of metaplastic cartilaginous nodes inside connective tissue of articular surfaces, is considered an active metaplastic phenomenon better ...

Last Updated: 1 Jan 2007

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Recurrent synovial chondromatosis of the knee after radical synovectomy and arthrodesis.
 

Author(s): J S Church, W H Breidahl, G C Janes

Journal: J Bone Joint Surg Br. 2006 May;88(5):673-5.

 

We describe a case of highly refractory synovial chondromatosis, which recurred despite four arthroscopic synovectomies, a chemical synovectomy, two open synovectomies and an arthrodesis. A review of the literature revealed one similar case. Both presented with marked joint stiffness ...

Last Updated: 28 Apr 2006

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[Isolated synovial chondromatosis of the subacromial bursa: report of a new case and review of the literature].
 

Author(s): M H Bouhaouala, W Saïd, M Haj Salah, N Bouaziz, S Mourali, S Chaabane

Journal: J Radiol. 2006 Jan;87(1):65-8.

 

Synovial chondromatosis is a rare metaplasia of the synovium of unknown etiology that may involve occasionally the subacromial bursa. We report a new case diagnosed by ultrasound in a 30-year-old man and we present pathogenetic, diagnostic and therapeutic features of this disease ...

Last Updated: 17 Jan 2006

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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