Susac syndrome

Common Name(s)

Susac syndrome

Susac syndrome is an autoimmune condition that affects very fine blood vessels in the brain, retina, and cochlea (inner ear). It is characterized by three main symptoms: encephalopathy (which can cause headache, mild memory loss, personality changes, and confusion); sensorineural hearing loss; and vision loss. Most people do not have all the symptoms of Susac syndrome at the beginning of their illness but develop symptoms over the course of several years. Susac syndrome affects women more than men and the age of onset is usually between 20 and 40 years. The cause of this condition is still unknown. Corticosteroids, antiplatelets, anticoagulation, and cyclophosphamide have been used to treat Susac syndrome. However, the extent to which individuals respond to treatment is not clear. Improvement may occur spontaneously although in some cases there may be residual dysfunction.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Susac syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Susac syndrome" returned 28 free, full-text research articles on human participants. First 3 results:

Susac syndrome.
 

Author(s): Fernando Freua, Leandro Tavares Lucato, Flávio Villela, Getúlio Daré Rabello

Journal: Arq Neuropsiquiatr. 2014 Oct;72(10):812-3.

 

Last Updated: 23 Oct 2014

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Susac syndrome: diverse clinical findings and treatment.
 

Author(s): Ricardo Canto Bardal, Emmerson Badaro, Jayme Arana, Fabio Alves, Eduardo Cunha de Souza, Pedro Paulo Bonomo, Ezequiel Portella, Mauricio Maia

Journal: Arq Bras Oftalmol. ;77(3):188-90.

 

We report a case of a 19-year-old woman presenting bilateral neurosensorial hearing loss, mental abnormalities, and loss of visual field in the left eye. Visual acuity was 20/20 in OD and 20/25 in OS. Patient was examined systemically. Audiometry showed sensorineural hearing loss ...

Last Updated: 9 Oct 2014

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Author reply: central retinal artery occlusion in a young female: Sneddon's syndrome versus Susac syndrome?
 

Author(s): Hyun Beom Song, Se Joon Woo

Journal: Korean J Ophthalmol. 2014 Feb;28(1):113-4.

 

Last Updated: 21 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Susac syndrome" returned 4 free, full-text review articles on human participants. First 3 results:

Diagnosis and classification of Susac syndrome.
 

Author(s): Mario García-Carrasco, Claudia Mendoza-Pinto, Ricard Cervera

Journal: Autoimmun Rev. ;13(4-5):347-50.

 

Susac syndrome (SS) is an autoimmune disease characterized by the clinical triad of encephalopathy, branch retinal artery occlusions and neuro-sensorial hearing loss; it is due to a microangiopathy affecting the precapillary arterioles of the brain, retina and inner ear. SS is characterized ...

Last Updated: 11 Mar 2014

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Susac syndrome as an example of a rare vasculopathy.
 

Author(s): Magdalena Olszanecka-Glinianowicz, Antoni Hrycek

Journal: Pol. Arch. Med. Wewn.. ;119(1-2):80-2.

 

Susac syndrome is a rare vasculopathy affecting small vessels of the brain, the retina and the cochlea. The pathogenesis of this syndrome is unknown. It is characterized by a triad of clinical symptoms, i.e. encephalopathy, visual disorders and hearing disorders. The aim of this work ...

Last Updated: 3 Apr 2009

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[Susac syndrome as a cause of sensorineural hearing loss].
 

Author(s): J D Cubillana Herrero, A Soler Valcárcel, I Albaladejo Devis, B Rodríguez González-Herrero, N Minguez Merlos, J A Jiménez Cervantes-Nicolás

Journal: Acta Otorrinolaringol Esp. 2002 May;53(5):379-83.

 

Susac's syndrome is an extremely rare clinical manifestation characterized by the triad of fluctuating sensorineural hearing loss, sudden visual loss and encephalopathy. Probably underdiagnosed, it affects young women who start the clinical history with headache, visual and hearing ...

Last Updated: 20 Aug 2002

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome
 

Status: Recruiting

Condition Summary: SUSAC's Syndrome; Encephalopathy; Hearing Loss; Retinal Artery Branch Occlusions

 

Last Updated: 13 Aug 2013

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Investigation of Biomarkers in Susac Syndrome
 

Status: Recruiting

Condition Summary: Susac Syndrome

 

Last Updated: 11 Feb 2013

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