Streptococcal Group B invasive disease

Common Name(s)

Streptococcal Group B invasive disease

Streptococcal Group B invasive disease is a bacterial infection caused by the streptococcus bacteria type B (strep B). Strep B normally lives without causing problems inside our digestive system and, in women, the vagina or birthing canal. While the rates of serious group B strep infections are much higher among newborns than among any other age group, serious group B strep infections occur in other age groups in both men and women. The rate is highest among adults 65 years of age and older. Most adult group B strep disease occurs in adults who have other medical conditions. These include: diabetes mellitus; cardiovascular disease; congestive heart failure; history of cancer; and obesity. The most common problems caused by group B strep in adults are bloodstream infections, pneumonia (infection in the lungs), skin and soft-tissue infections, and bone and joint infections. Rarely in adults, group B strep can cause meningitis (infection of the fluid and lining surrounding the brain). Depending on the area infected with the bacteria the symptoms varies. The common symptoms shared with all types of this disease include, fever, headache, malaise (feeling of uneasiness), localized pain. The source of infection for adults is unknown. If doctors suspect an adult has an invasive group B strep infection, they will take a sample of sterile body fluids, such as blood or spinal fluid. Group B strep disease is diagnosed when the bacteria are grown in the laboratory from samples of those fluids. Samples take a few days to grow. Sometimes group B strep can cause mild disease in adults, such as urinary tract infections (UTIs, also called bladder infections), which also can be diagnosed in the lab with a sample of urine. roup B strep infections are usually treated with penicillin or other common antibiotics. Sometimes soft tissue and bone infections may need surgery. Treatment will vary according to the kind of infection with group B strep someone has, and patients

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Condition Specific Organizations

Following organizations serve the condition "Streptococcal Group B invasive disease" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Streptococcal Group B invasive disease" returned 10 free, full-text research articles on human participants. First 3 results:

Invasive bacterial disease trends and characterization of group B streptococcal isolates among young infants in southern Mozambique, 2001-2015.
 

Author(s): Betuel Sigaúque, Miwako Kobayashi, Delfino Vubil, Ariel Nhacolo, Alberto Chaúque, Benild Moaine, Sérgio Massora, Inácio Mandomando, Tacilta Nhampossa, Quique Bassat, Fabiana Pimenta, Clara Menéndez, Maria da Gloria Carvalho, Eusebio Macete, Stephanie J Schrag

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Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease ...

Last Updated: 31 Dec 1969

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Epidemiology of invasive group B streptococcal disease in infants from urban area of South China, 2011-2014.
 

Author(s): Xiaoshan Guan, Xiaoping Mu, Wenjing Ji, Chunlei Yuan, Ping He, Lian Zhang, Yanfen Huang, Juan Li, Jianfeng Chen, Huamin Zhong, Shuyin Pang, Nan Tan, Qiulian Deng, Kankan Gao, Yu-Ping Huang, Chien-Yi Chang, Haiying Liu

Journal:

 

Group B Streptococcus (GBS) is a leading cause of morbidity and mortality in infants in both developed and developing countries. To our knowledge, only a few studies have been reported the clinical features, treatment and outcomes of the GBS disease in China. The severity of neonatal ...

Last Updated: 31 Dec 1969

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Immune Responses to Invasive Group B Streptococcal Disease in Adults.
 

Author(s): Morven S Edwards, Marcia A Rench, C Daniela Rinaudo, Monica Fabbrini, Giovanna Tuscano, Giada Buffi, Erika Bartolini, Stefano Bonacci, Carol J Baker, Immaculada Margarit

Journal: Emerging Infect. Dis.. 2016 11;22(11):1877-1883.

 

Immunization of nonpregnant adults could help prevent invasive group B Streptococcus (GBS) infections, but adult immune responses have not been investigated. We defined capsular polysaccharide (CPS) and pilus island (PI) surface antigen distribution and expression and immune responses ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Streptococcal Group B invasive disease" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Burden of Invasive Group B Streptococcal Disease in Infants and Resistance Surveillance in China
 

Status: Recruiting

Condition Summary: Invasive Group B Streptococcal Disease

 

Last Updated: 21 Jun 2016

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