Stomach cancer

Common Name(s)

Stomach cancer, Gastric cancer, Stomach carcinoma

Stomach cancer is a type of cancer that begins in the lining of the stomach. Stomach cancer occurs when cells in the stomach develop mutations that result in the cells dividing rapidly and resisting death. Those cells form a tumor.

Early signs of stomach cancer include indigestion, bloating, heartburn, nausea, and loss of appetite. As the cancer develops, symptoms may include stomach pain, vomiting, weight loss, stomach swelling, difficulty swallowing, diarrhea, constipation, bloody stool, yellowing of the skin or eyes (jaundice), weakness, and exhaustion.

Risk factors for stomach cancer include having long-term iron deficiency (anemia), being infected with the bacteria H. pylori, Epstein-Barr virus infection, having stomach growths called polyps, having stomach surgery to remove ulcers, having type-A blood, smoking, obesity, being exposed to chemicals or asbestos, and eating foods that have been smoked or are high in sodium. Certain genes also increase one’s risk of developing stomach cancer.

There are several tests used to diagnose stomach cancer. In a procedure called an endoscopy, a doctor puts a narrow tube with a camera down the patient’s throat to view the stomach. Blood tests, X-ray imaging (upper GI series test), and computed tomography (CT) scans can also be used to diagnose stomach cancer. A procedure called a biopsy can be used to collect and analyze a tissue sample from the stomach to check for cancer cells. Additional tests may be performed to determine the stage of the disease.

Treatment for stomach cancer often involves surgical removal of parts of the stomach and surrounding tissues. Chemotherapy, radiation therapy, or targeted drugs may also be used. If you have been diagnosed with stomach cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Stomach cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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No Stomach For Cancer

Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.

Last Updated: 7 Jan 2016

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Stomach cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
No Stomach For Cancer

Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.

http://www.nostomachforcancer.org

Last Updated: 7 Jan 2016

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Stomach cancer" returned 440 free, full-text research articles on human participants. First 3 results:

Analysis of Relationships between Altitude and Distance from Volcano with Stomach Cancer Incidence Using a Geographic Information System.
 

Author(s): F Amani, S Sadeghieh Ahari, S Barzegari, B Hassanlouei, M Sadrkabir, Esmaeil Farzaneh

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(16):6889-94.

 

Gastric cancer (GC) is the fifth most common cancer in the world, with a wide variation in incidence rates across different geographical areas. In Iran GC is the most common cancer in males and it is reported to be the third most prevalent after breast and colorectal in females. A ...

Last Updated: 30 Oct 2015

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XRCC1 Gene Polymorphism, Clinicopathological Characteristics and Stomach Cancer Survival in Thailand.
 

Author(s): Nuntiput Putthanachote, Supannee Promthet, Krittika Suwanrungruan, Peechanika Chopjitt, Surapon Wiangnon, Li-Sheng Chen, Ming-Fang Yen, Tony Hsiu-Hsi Chen

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(14):6111-6.

 

Stomach cancer is one of leading causes of death worldwide. In Thailand, the incidence and mortality of stomach cancer are in the top ten for cancers. Effects of DNA repair gene X-ray repair cross complementary protein 1 (XRCC1) polymorphisms and clinicopathological characteristics ...

Last Updated: 31 Aug 2015

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Co-Expression of NEU2 and GBA3 Causes a Drastic Reduction in Cytosolic Sialyl Free N-glycans in Human MKN45 Stomach Cancer Cells-Evidence for the Physical Interaction of NEU2 and GBA3.
 

Author(s): Li Wang, Junichi Seino, Haruna Tomotake, Yoko Funakoshi, Hiroto Hirayama, Tadashi Suzuki

Journal:

 

It is well known that the "free" form of glycans that are structurally related to asparagine (N)-linked glycans ("free N-glycans") are found in a wide variety of organisms. The mechanisms responsible for the formation/degradation of high mannose-type free N-glycans have been extensively ...

Last Updated: 21 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Stomach cancer" returned 25 free, full-text review articles on human participants. First 3 results:

ACR Appropriateness Criteria® Resectable Stomach Cancer.
 

Author(s): Parima Daroui, Salma K Jabbour, Joseph M Herman, May Abdel-Wahab, Nilofer Azad, A William Blackstock, Prajnan Das, Karyn A Goodman, Theodore S Hong, William E Jones, Harmeet Kaur, Andre A Konski, Albert C Koong, Rachit Kumar, Timothy M Pawlik, William Small, Charles R Thomas, W Warren Suh

Journal: Oncology (Williston Park, N.Y.). 2015 Aug;29(8):595-602, C3.

 

For resectable gastric cancer, perioperative chemotherapy or adjuvant chemoradiation with chemotherapy are standards of care. The decision making for adjuvant therapeutic management can depend on the stage of the cancer, lymph node positivity, and extent of surgical resection. After ...

Last Updated: 18 Aug 2015

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The role of three-dimensional multidetector CT gastrography in the preoperative imaging of stomach cancer: emphasis on detection and localization of the tumor.
 

Author(s): Jin Woong Kim, Sang Soo Shin, Suk Hee Heo, Hyo Soon Lim, Nam Yeol Lim, Young Kyu Park, Yong Yeon Jeong, Heoung Keun Kang

Journal: Korean J Radiol. ;16(1):80-9.

 

Multidetector CT (MDCT) gastrography has been regarded as a promising technique for the preoperative imaging of gastric cancer. It has the ability to produce various three-dimensional (3D) images. Because 3D reconstruction images are more effective and intuitive for recognizing abnormal ...

Last Updated: 19 Jan 2015

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Gastric cancer arising from the remnant stomach after distal gastrectomy: a review.
 

Author(s): Shinsuke Takeno, Tatsuya Hashimoto, Kenji Maki, Ryosuke Shibata, Hironari Shiwaku, Ippei Yamana, Risako Yamashita, Yuichi Yamashita

Journal: World J. Gastroenterol.. 2014 Oct;20(38):13734-40.

 

Gastric stump carcinoma was initially reported by Balfore in 1922, and many reports of this disease have since been published. We herein review previous reports of gastric stump carcinoma with respect to epidemiology, carcinogenesis, Helicobacter pylori (H. pylori) infection, Epstein-Barr ...

Last Updated: 16 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study Comparing Billroth II With Roux-en-Y Reconstruction for Gastric Cancer
 

Status: Recruiting

Condition Summary: Gastric Cancer; Stomach Cancer; Gastrectomy

 

Last Updated: 13 Apr 2012

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Prognosis and Risk Factors of Gastric Cancer in Patients With Intestinal Metaplasia
 

Status: Recruiting

Condition Summary: Stomach Cancer

 

Last Updated: 19 Dec 2014

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Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer
 

Status: Recruiting

Condition Summary: Gastric Cancer; Stomach Cancer; Esophageal Cancer

 

Last Updated: 6 May 2016

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