Still's disease adult onset

Common Name(s)

Still's disease adult onset

Adult-onset Still's disease is an inflammatory condition characterized by high fevers, rash, sore throat, and joint pain. As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications.  Still's disease was named after an English doctor named George Still, who described the condition in children in 1896. Still's disease which occurs in children (those under the age of 16) is now known as systemic onset juvenile rheumatoid arthritis (JRA). In 1971, the term "adult Still's disease" was used to describe adults who had a condition similar to systemic onset JRA.  The cause of adult-onset Still's disease is unknown. No risk factors for the disease have been identified. There's no cure for adult-onset Still's disease; however, treatment may offer symptom relief and help prevent complications.

 

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Still's disease adult onset" for support, advocacy or research.

International Still's Disease Foundation, Inc.

The purpose and Mission Statement of the International Still's Disease Foundation is to: * Provide support to those who live with Still’s Disease. * Encourage and facilitate communication between people living with, and those impacted by, Still’s Disease. * Provide up-to-date information on Still’s Disease research, treatments and related studies to those with the disease, their families, friends, and health care workers. * Increase general awareness of Still’s to the public.

Last Updated: 8 May 2014

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The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

Last Updated: 16 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Still's disease adult onset" for support, advocacy or research.

International Still's Disease Foundation, Inc.

The purpose and Mission Statement of the International Still's Disease Foundation is to: * Provide support to those who live with Still’s Disease. * Encourage and facilitate communication between people living with, and those impacted by, Still’s Disease. * Provide up-to-date information on Still’s Disease research, treatments and related studies to those with the disease, their families, friends, and health care workers. * Increase general awareness of Still’s to the public.

http://www.stillsdisease.org

Last Updated: 8 May 2014

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The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

http://www.nomidalliance.org

Last Updated: 16 Aug 2013

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General Support Organizations

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General Resources

Still's Disease Video Series

This four part video series can be viewed on our website without being downloaded. It is a free informational series presented by Dr. John J. Cush, on the History, Manifestations, Diagnosis and Management of Still's disease.

Updated 8 Feb 2014

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Still's Disease Free Informational Brochure

Free informational brochure about Adult-onset Still's disease, it's symptoms, medications and helpful information. Will be mailed via USPS to all addresses Internationally.

Updated 8 Feb 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Still's disease adult onset" returned 101 free, full-text research articles on human participants. First 3 results:

Demyelinating encephalopathy in adult onset Still's disease: case report and review of the literatures.
 

Author(s): Wang Jie, Li Miao, Shao Yankun, Yang Hong, Xu Zhongxin

Journal: Clin Neurol Neurosurg. 2013 Oct;115(10):2213-6.

 

Last Updated: 23 Sep 2013

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N2010 adult-onset Still's disease complicated by hemophagocytic syndrome and catastrophic antiphospholipid syndrome resulting in four limb amputation.
 

Author(s): Sarah Sacks, James Finn, Giovanni Sanna, Munther A Khamashta, Fatts Chowdhury, Beverley J Hunt, Rachel Bell, David P D'Cruz

Journal: Isr. Med. Assoc. J.. 2013 Apr;15(4):192-4.

 

Last Updated: 20 Jun 2013

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Prurigo pigmentosa-like persistent papules and plaques in a patient with adult-onset Still's disease.
 

Author(s): Yung-Tsu Cho, Yi-Hua Liao

Journal: Acta Derm. Venereol.. 2014 Jan;94(1):102-3.

 

Last Updated: 9 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Still's disease adult onset" returned 10 free, full-text review articles on human participants. First 3 results:

Adult onset Still's disease as a paraneoplastic syndrome--a case report and review of the literature.
 

Author(s): Sedat Yilmaz, Ahmet Karakas, Muhammet Cinar, Omer Coskun, Ismail Simsek, Hakan Erdem, Can Polat Eyigun, Salih Pay

Journal: Bull Hosp Jt Dis (2013). 2013 ;71(2):156-60.

 

Adult onset Still's disease (AOSD) is a systemic inflammatory disease with unknown etiology and characterized by evanescent salmon pink rash, sore throat, liver dysfunction, lymphadenopathy, hepatosplenomegaly, arthritis, and leukocytosis. It is a diagnosis of exclusion; however, ...

Last Updated: 16 Sep 2013

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Adult-onset Still's disease complicated by autoimmune hepatitis: successful treatment with infliximab.
 

Author(s): Kenji Fujii, Ryo Rokutanda, Yasuhiro Osugi, Yoshinobu Koyama, Toshiyuki Ota

Journal: Intern. Med.. 2012 ;51(9):1125-8.

 

A 17-year-old woman was previously diagnosed with autoimmune hepatitis (AIH) by liver biopsy. Adult-onset Still's disease (AOSD) was subsequently diagnosed on the basis of high fever, arthralgia, erythema, leukocytosis (>80% granulocytes), cervical lymph node swelling, splenomegaly, ...

Last Updated: 11 May 2012

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[Simultaneous relapse of Basedow's disease in a patient with adult-onset Still's disease].
 

Author(s): Masataka Torigoe, Tomoya Miyamura, Masataka Nakamura, Yoshirou Hourai, Yoshie Hirata, Jin Ando, Soichiro Takahama, Rumi Minami, Masahiro Yamamoto, Eiichi Suematsu

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2011 ;34(5):426-30.

 

This report describes a 50-year-old woman with coexisting Basedow's disease and adult-onset Still's disease (AOSD) that relapsed simultaneously. She was diagnosed with Basedow's disease in 1999, and treatment with antithyroid agents was started. However, the treatment was soon stopped ...

Last Updated: 1 Nov 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Canakinumab for Treatment of Adult Onset Still's Disease
 

Status: Recruiting

Condition Summary: Adult-Onset Still´s Disease

 

Last Updated: 29 Jul 2014

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Efficacy and Safety of Tocilizumab in Adult's Still Disease
 

Status: Not yet recruiting

Condition Summary: Adult's Still Disease

 

Last Updated: 26 Oct 2009

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Glycosylated Ferritin in Macrophagic Activation Syndromes
 

Status: Recruiting

Condition Summary: Still's Disease, Adult-Onset; Sepsis; Macrophagic Activation Syndrome

 

Last Updated: 20 May 2014

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