Autoimmune Myocarditis

Common Name(s)

Autoimmune Myocarditis

Autoimmune Myocarditis is an inflammation of the myocardium, the middle layer of the heart wall. Autoimmune myocarditis occurs when the body mistakingly used its own immune system to attack healthy heart cells. Signs and symptoms of myocarditis include chest pain, heart failure, abnormal heart rhythms, and shortness of breath during exercise. If myocarditis becomes severe, the pumping action of the heart weakens, and the heart won't be able to supply the rest of the body with enough blood. Clots also could form in the heart, leading to a stroke or heart attack. Several thousand people in the United Sates are diagnosed with myocarditis each year (but not necessarily autoimmune myocarditis). Diagnosis may include several different tests, including: EEG (to measure electrical activity of the heart), chest X-ray, heart biopsy, and cardiac MRI. Treatment typically involves medications to prevent heart failure. In addition, rest and low-salt diets are recommended, and steroids can be used to reduce inflammation.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Myocarditis" for support, advocacy or research.

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The Myocarditis Foundation

The Myocarditis Foundation is dedicated to providing information and support related to the causes, symptoms, diagnosis, and treatment of myocarditis. The Myocarditis Foundation's mission is to educate physicians and the public about this disease, support the patients and their families who have been affected by myocarditis, and ultimately fund research to find ways to better diagnose, treat, and prevent myocarditis.

Last Updated: 29 Nov 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Myocarditis" for support, advocacy or research.

Logo
The Myocarditis Foundation

The Myocarditis Foundation is dedicated to providing information and support related to the causes, symptoms, diagnosis, and treatment of myocarditis. The Myocarditis Foundation's mission is to educate physicians and the public about this disease, support the patients and their families who have been affected by myocarditis, and ultimately fund research to find ways to better diagnose, treat, and prevent myocarditis.

http://www.myocarditisfoundation.org

Last Updated: 29 Nov 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Myocarditis" returned 27 free, full-text research articles on human participants. First 3 results:

Biopsy-proven autoimmune myocarditis in HIV-associated dilated cardiomyopathy.
 

Author(s): Andrea Frustaci, Nicola Petrosillo, Marco Francone, Romina Verardo, Giuseppe Ippolito, Cristina Chimenti

Journal:

 

Dilated cardiomyopathy occurring in HIV-infected patients raises both diagnostic and therapeutic challenging problems. Indeed myocardial involvement in HIV infection has been variously attributed to several causes, including viral, toxic, nutritional and autoimmune, but no specific ...

Last Updated: 14 Jul 2015

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Autoimmune myocarditis, valvulitis, and cardiomyopathy.
 

Author(s): Jennifer M Myers, DeLisa Fairweather, Sally A Huber, Madeleine W Cunningham

Journal: Curr Protoc Immunol. 2013 ;Chapter 15():Unit 15.14.1-51.

 

Myocarditis and valvulitis are inflammatory diseases affecting myocardium and valve. Myocarditis, a viral-induced disease of myocardium, may lead to dilated cardiomyopathy and loss of heart function. Valvulitis leads to deformed heart valves and altered blood flow in rheumatic heart ...

Last Updated: 8 Apr 2013

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Mononuclear cell secretome in autoimmune myocarditis.
 

Author(s): Carsten Skurk, Heinz-Peter Schultheiss

Journal: Eur. Heart J.. 2015 Mar;36(11):650-2.

 

Last Updated: 16 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Myocarditis" returned 5 free, full-text review articles on human participants. First 3 results:

Unresolved issues in theories of autoimmune disease using myocarditis as a framework.
 

Author(s): Robert Root-Bernstein, DeLisa Fairweather

Journal: J. Theor. Biol.. 2015 Jun;375():101-23.

 

Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander ...

Last Updated: 2 May 2015

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Experimental drugs for treatment of autoimmune myocarditis.
 

Author(s): Lina Han, Shuli Guo, Yutang Wang, Liming Yang, Siyu Liu

Journal: Chin. Med. J.. 2014 ;127(15):2850-9.

 

To review the experimental drugs for the treatment of autoimmune myocarditis.

Last Updated: 22 Aug 2014

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Genetic complexity of autoimmune myocarditis.
 

Author(s): Haiyan S Li, Davinna L Ligons, Noel R Rose

Journal: Autoimmun Rev. 2008 Jan;7(3):168-73.

 

Autoimmune myocarditis, a chronic stage of myocardial inflammation, occurs in a small subset of patients after acute cardiotropic viral infection and can lead to dilated cardiomyopathy (DCM). This disease can be recapitulated in susceptible mouse strains by infection with coxsackievirus ...

Last Updated: 14 Jan 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Myocardial Inflammation in Systemic Lupus Erythematosus
 

Status: Recruiting

Condition Summary: SLE

 

Last Updated: 23 Jan 2014

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