Spondyloarthritis

Common Name(s)

Spondyloarthritis, Spondyloarthropathy

Spondyloarthritis (or spondyloarthropathy) is a group of inflammatory diseases that cause arthritis in the sites where tendons and ligaments attach to bones (entheses). There are six forms of spondyloarthritis. The most common is ankylosing spondylitis, which mainly affects the spine. Other diseases in the spondyloarthritis family include axial spondyloarthritis (which affects mainly the spine and pelvic joints), peripheral spondyloarthritis (which affects mostly the arms and legs), reactive arthritis (Reiter’s syndrome), psoriatic arthritis, and enteropathic arthritis/spondylitis associated with inflammatory bowel diseases.

Signs and symptoms of spondyloarthritis varies depending on the disease. However, symptoms typically present with redness and swelling (inflammation) that causes pain and stiffness, usually in the spine. Some forms can affect the hands, feet, arms and legs. Another symptom includes destruction of bone that causes spine abnormalities (deformity). Additional complications of spondyloarthritis may include eye inflammation, compression fractures and heart problems. Symptoms usually begin around late adolescence or early adulthood. The exact cause of the spondyloarthritis group of diseases is unknown. They are believed to be due to a combination of genetic and environmental factors. Individuals with the HLA-B27 form of the HLA-B gene are at greater risk of developing ankylosing spondylitis, the most common type of spondyloarthritis.

To diagnose spondyloarthritis, your doctor will gather a medical history and perform a physical exam. In addition, they may collect images of the affected areas. There is no cure for spondyloarthritis, but treatment can include medications to decrease pain. If you or your child has been diagnosed with spondyloarthritis, talk with your doctor to discuss the current treatment options. Support groups can provide additional information and connect you with others.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spondyloarthritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spondyloarthritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spondyloarthritis" returned 191 free, full-text research articles on human participants. First 3 results:

Does evaluation of the ligamentous compartment enhance diagnostic utility of sacroiliac joint MRI in axial spondyloarthritis?
 

Author(s): Ulrich Weber, Walter P Maksymowych, Stanley M Chan, Kaspar Rufibach, Susanne J Pedersen, Zheng Zhao, Veronika Zubler, Mikkel Østergaard, Robert G W Lambert

Journal:

 

Inflammation of the sacroiliac joints (SIJ) is a fundamental clinical feature of axial spondyloarthritis (SpA). The anatomy of the irregularly shaped SIJ is complex with an antero-inferior cartilaginous compartment containing central hyaline and peripheral fibrocartilage, and a dorso-superior ...

Last Updated: 14 Sep 2015

Go To URL
[A brief magnetic resonance imaging protocol for spondyloarthritis].
 

Author(s): Giancarlo Schiappacasse F, Jorge Díaz J, Pablo Alvayay Q

Journal: Rev Med Chil. 2015 Jul;143(7):905-12.

 

Spondyloarthritis is a group of diseases that seriously hampers quality of life. Diagnostic criteria, in which images play an important role, have evolved over time. The most recent diagnostic criteria, published in 2009, included magnetic resonance imaging (MRI) of the sacroiliac ...

Last Updated: 12 Sep 2015

Go To URL
Acute anterior uveitis and other extra-articular manifestations of spondyloarthritis.
 

Author(s): T C Mitulescu, C Popescu, A Naie, D Predeţeanu, V Popescu, C Alexandrescu, L M Voinea

Journal: J Med Life. ;8(3):319-25.

 

Spondyloarthritis (SpA) is associated with an array of peripheral manifestations. Our study aims to evaluate extra-articular manifestations of SpA in a Romanian academic clinical setting and to observe their associations with different disease measures.

Last Updated: 9 Sep 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spondyloarthritis" returned 48 free, full-text review articles on human participants. First 3 results:

Non-Radiographic Axial Spondyloarthritis.
 

Author(s): Gleb Slobodin, Iris Eshed

Journal: Isr. Med. Assoc. J.. 2015 Dec;17(12):770-6.

 

The term non-radiographic axial spondyloarthritis (nrAxSpA) was coined for patients who have a clinical picture of ankylosing spondylitis (AS) but do not exhibit radiographic sacroiliitis. The ASAS classification criteria for nrAxSpA, ensuring the recruitment of homogenous study cohorts, ...

Last Updated: 22 Feb 2016

Go To URL
Clinical Tools to Assess and Monitor Spondyloarthritis.
 

Author(s): Robert Landewé, Astrid van Tubergen

Journal: Curr Rheumatol Rep. 2015 Jul;17(7):47.

 

Assessment and monitoring is important in diseases affecting multiple sites and organs, such as axial spondyloarthritis (axSpA) that may have several signs and symptoms, and for which several treatments are available. Instruments for assessment and monitoring should be appropriately ...

Last Updated: 11 Jun 2015

Go To URL
Development of an ASAS-endorsed recommendation for the early referral of patients with a suspicion of axial spondyloarthritis.
 

Author(s): Denis Poddubnyy, Astrid van Tubergen, Robert Landewé, Joachim Sieper, Désirée van der Heijde,

Journal: Ann. Rheum. Dis.. 2015 Aug;74(8):1483-7.

 

The aim of this work was to develop a consensual recommendation under the auspices of the Assessment of SpondyloArthritis international Society (ASAS) for early referral of patients with a suspicion of axial spondyloarthritis by non-rheumatologists. The development of a referral recommendation ...

Last Updated: 10 Jul 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 May 2016

Go to URL

Last Updated: 17 Mar 2015

Go to URL

Last Updated: 10 May 2016

Go to URL