Splenomegaly

Common Name(s)

Splenomegaly

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Splenomegaly" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Splenomegaly" returned 137 free, full-text research articles on human participants. First 3 results:

Treatment of suspected hyper-reactive malarial splenomegaly (HMS) in pregnancy with mefloquine.
 

Author(s): Juthamas Jaroensuk, Nicole Stoesser, Mara L Leimanis, Podjanee Jittamala, Nicholas J White, Francois H Nosten, Rose McGready

Journal: Am. J. Trop. Med. Hyg.. 2014 Apr;90(4):609-11.

 

Malaria infections in pregnancy are associated with adverse outcomes for both mother and child. There are few data on hyper-reactive malarial splenomegaly, an aberrant immunological response to chronic or recurrent malaria in pregnancy. This retrospective assessment reviewed the impact ...

Last Updated: 3 Apr 2014

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A case of liver fibrosis with splenomegaly after oxaliplatin-based adjuvant chemotherapy for colon cancer.
 

Author(s): Gu Hyum Kang, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong, Heon Young Lee, Dae Young Kang

Journal: J. Korean Med. Sci.. 2013 Dec;28(12):1835-8.

 

Previous studies reported that oxaliplatin is associated with sinusoidal obstruction syndrome. However few reports on oxaliplatin induced liver fibrosis are found in the literature. Furthermore pathogenesis of liver fibrosis is not well known. We report a case of 45-yr-old Korean ...

Last Updated: 16 Dec 2013

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The learning curve for laparoscopic splenectomy for massive splenomegaly: a single surgeon's experience.
 

Author(s): Zhong Wu, Jin Zhou, Yun-qiang Cai, Shi-an Liu, Bing Peng

Journal: Chin. Med. J.. 2013 ;126(11):2103-8.

 

Laparoscopic splenectomy (LS) for massive splenomegaly is more technically challenging than for a normal-sized spleen. The purpose of this study was to determine the effect of operative experience on perioperative outcomes of LS for massive splenomegaly.

Last Updated: 17 Jun 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Splenomegaly" returned 5 free, full-text review articles on human participants. First 3 results:

[Drug--induced splenomegaly].
 

Author(s): Andy Petroianu

Journal: Acta Med Port. 2011 Dec;24 Suppl 4():977-82.

 

The diagnosis of splenomegaly due to drugs is based on a recent history of exposure to a drug before the spleen enlargement. The purpose of this paper is to review studies of the literature on drugs that may induce to splenomegaly. Drugs may provoke the enlargement of spleen by direct ...

Last Updated: 6 Aug 2012

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Splenomegaly in myelofibrosis--new options for therapy and the therapeutic potential of Janus kinase 2 inhibitors.
 

Author(s): Jasleen Randhawa, Alen Ostojic, Radovan Vrhovac, Ehab Atallah, Srdan Verstovsek

Journal:

 

Splenomegaly is a common sign of primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), and post-essential thrombocythemia myelofibrosis (post-ET MF) that is associated with bothersome symptoms, which have a significant negative impact on patients' quality ...

Last Updated: 13 Sep 2012

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How I treat symptomatic splenomegaly in patients with myelofibrosis.
 

Author(s): Ruben A Mesa

Journal: Blood. 2009 May;113(22):5394-400.

 

Managing patients with myelofibrosis (MF), either those with primary MF or those whose MF has evolved from antecedent polycythemia vera or essential thrombocythemia, presents many challenges to the hematologist. MF patients have a range of debilitating disease manifestations (eg, ...

Last Updated: 29 May 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of the Impact of Hypersplenism and Splenectomy on Hepatocarcinogenesis in Patients With Posthepatitic Cirrhosis
 

Status: Recruiting

Condition Summary: Liver Cirrhosis; Carcinoma, Hepatocellular; Splenomegaly; Laparotomy

 

Last Updated: 13 Sep 2010

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Oral Pacritinib Versus Best Available Therapy to Treat Myelofibrosis With Thrombocytopenia
 

Status: Recruiting

Condition Summary: Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis

 

Last Updated: 28 Aug 2014

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Hemolysis in Patients With Hereditary Spherocytosis (HS)
 

Status: Not yet recruiting

Condition Summary: Hereditary; Hemolysis

 

Last Updated: 13 Sep 2010

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