Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the bodyÕs immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Logo
American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 320 free, full-text research articles on human participants. First 3 results:

Severe autoimmune hemolytic anemia in a patient with chronic hepatitis C during treatment with Peg interferon alfa-2a and ribavirin.
 

Author(s): Rym Ennaifer, Myriam Cheikh, Hayfa Romdhane, Rania Hefaiedh, Houda Ben Nejma, Najet Bel Hadj

Journal: Tunis Med. 2014 Jan;92(1):42-3.

 

Last Updated: 2 Jun 2014

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Autoimmune-associated hemophagocytic syndrome originating from autoimmune hepatitis with a successful response to therapy.
 

Author(s): Masaya Saito, Yoshihiko Yano, Akihiro Minami, Kenji Momose, Hirotaka Hirano, Takashi Yamasaki, Tomoo Itoh, Masaru Yoshida, Takeshi Azuma

Journal: Intern. Med.. 2014 ;53(2):103-7.

 

The patient was a 15-year-old girl with severe acute hepatitis. A liver biopsy showed the typical findings of autoimmune hepatitis (AIH). Subsequently, two lineages of cytopenia were found in the patient's peripheral blood. Hemophagocytosis by macrophages was observed in the bone ...

Last Updated: 16 Jan 2014

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Co-development of autoimmune hepatitis and Sjögren's syndrome triggered by the administration of herbal medicines.
 

Author(s): Hyo Jeong Oh, Young Mi Mok, Moon Seong Baek, Ji Kyeong Lee, Bong Soo Seo, Tae Hyeon Kim, Keum Ha Choi, In Kyeom Hwang, Ji Eun Ra, Yong-Reol Oh, Yong Sung Kim, Eun Young Cho, Haak Cheoul Kim, Young Woo Sohn

Journal: Clin Mol Hepatol. 2013 Sep;19(3):305-8.

 

Autoimmune hepatitis (AIH) has been reported in association with Sjögren's syndrome (SS). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and SS in a 53-year-old woman after the consumption of herbal medicines is described. After admission, the ...

Last Updated: 17 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 47 free, full-text review articles on human participants. First 3 results:

Challenges in the diagnosis and management of autoimmune hepatitis.
 

Author(s): Albert J Czaja

Journal: Can. J. Gastroenterol.. 2013 Sep;27(9):531-9.

 

Autoimmune hepatitis has diverse clinical phenotypes and outcomes that challenge current diagnostic criteria and management algorithms.

Last Updated: 30 Sep 2013

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Autoimmune hepatitis in childhood: the role of genetic and immune factors.
 

Author(s): Priscila Menezes Ferri Liu, Débora Marques de Miranda, Eleonora Druve Tavares Fagundes, Alexandre Rodrigues Ferreira, Ana Cristina Simões e Silva

Journal: World J. Gastroenterol.. 2013 Jul;19(28):4455-63.

 

Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies ...

Last Updated: 31 Jul 2013

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Diagnosis and management of the overlap syndromes of autoimmune hepatitis.
 

Author(s): Albert J Czaja

Journal: Can. J. Gastroenterol.. 2013 Jul;27(7):417-23.

 

Autoimmune hepatitis may have cholestatic features that are outside the classical phenotype and that resemble findings in other immune-mediated liver diseases. These cholestatic phenotypes have been designated 'overlap syndromes'.

Last Updated: 17 Jul 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 28 Jan 2014

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 24 Feb 2014

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Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 26 Jul 2010

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