Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 425 free, full-text research articles on human participants. First 3 results:

[Pharmaceutical care for a patient with warfarin-induced autoimmune hepatitis].
 

Author(s): Wei Liu, Lu Li, Jie Xu, Chao Zhang

Journal: Beijing Da Xue Xue Bao. 2016 Feb;48(1):183-6.

 

Here we reported a patient with warfarin-induced autoimmune hepatitis (AIH), and explored new concerns for the pharmaceutical care of warfarin. A 57- year-old woman was admitted to hospital for repeated anorexia, abdominal pain and abnormal liver function. She received prosthetic ...

Last Updated: 18 Feb 2016

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Exploring the Role of Killer Cell Immunoglobulin-Like Receptors and Their HLA Class I Ligands in Autoimmune Hepatitis.
 

Author(s): Roberto Littera, Luchino Chessa, Simona Onali, Francesco Figorilli, Sara Lai, Luca Secci, Giorgio La Nasa, Giovanni Caocci, Marcella Arras, Maurizio Melis, Sara Cappellini, Cinzia Balestrieri, Giancarlo Serra, Maria Conti, Teresa Zolfino, Michele Casale, Stefania Casu, Maria Cristina Pasetto, Lucia Barca, Claudia Salustro, Laura Matta, Rosetta Scioscia, Fausto Zamboni, Gavino Faa, Sandro Orrù, Carlo Carcassi

Journal:

 

Natural killer cells are involved in the complex mechanisms underlying autoimmune diseases but few studies have investigated their role in autoimmune hepatitis. Killer immunoglobulin-like receptors are key regulators of natural killer cell-mediated immune responses.

Last Updated: 9 Jan 2016

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Circulating microRNA Profiles in Patients with Type-1 Autoimmune Hepatitis.
 

Author(s): Kiyoshi Migita, Atsumasa Komori, Hideko Kozuru, Yuka Jiuchi, Minoru Nakamura, Michio Yasunami, Hiroshi Furukawa, Seigo Abiru, Kazumi Yamasaki, Shinya Nagaoka, Satoru Hashimoto, Shigemune Bekki, Hiroshi Kamitsukasa, Yoko Nakamura, Hajime Ohta, Masaaki Shimada, Hironao Takahashi, Eiji Mita, Taizo Hijioka, Haruhiro Yamashita, Hiroshi Kouno, Makoto Nakamuta, Keisuke Ario, Toyokichi Muro, Hironori Sakai, Kazuhiro Sugi, Hideo Nishimura, Kaname Yoshizawa, Takeaki Sato, Atsushi Naganuma, Tatsuji Komatsu, Yukio Oohara, Fujio Makita, Minoru Tomizawa, Hiroshi Yatsuhashi

Journal:

 

Recent studies have demonstrated that micro (mi)RNA molecules can be detected in the circulation and can serve as potential biomarkers of various diseases. This study used microarray analysis to identify aberrantly expressed circulating miRNAs in patients with type 1 autoimmune hepatitis ...

Last Updated: 20 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 72 free, full-text review articles on human participants. First 3 results:

Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis.
 

Author(s): Pascal Lapierre, Alain Lamarre

Journal: J Immunol Res. 2015 ;2015():479703.

 

In both autoimmune liver disease and chronic viral hepatitis, the injury results from an immune-mediated cytotoxic T cell response to liver cells. As such, it is not surprising that CD4(+) regulatory T cells, a key regulatory population of T cells able to curb immune responses, could ...

Last Updated: 24 Jun 2015

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Autoimmune hepatitis: recent advances in the pathogenesis and new diagnostic guidelines in Japan.
 

Author(s): Hiromasa Ohira, Kazumichi Abe, Atsushi Takahashi, Hiroshi Watanabe

Journal: Intern. Med.. 2015 ;54(11):1323-8.

 

Autoimmune hepatitis (AIH) is thought to be associated with various genetic and immunological abnormalities. Concerning the pathogenesis of AIH, increasing attention has been paid to genome-wide association studies, toll-like receptors and Treg/Th17 balance. For Japanese patients ...

Last Updated: 1 Jun 2015

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Autoimmune hepatitis--Update 2015.
 

Author(s): Michael P Manns, Ansgar W Lohse, Diego Vergani

Journal: J. Hepatol.. 2015 Apr;62(1 Suppl):S100-11.

 

Last Updated: 29 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 6 Jan 2016

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Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 26 Jul 2010

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 6 Jan 2016

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