Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 467 free, full-text research articles on human participants. First 3 results:

Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study.
 

Author(s): Åsa D Borssén, Richard Palmqvist, Stergios Kechagias, Hanns-Ulrich Marschall, Annika Bergquist, Fredrik Rorsman, Ola Weiland, Hans Verbaan, Nils Nyhlin, Emma Nilsson, Mårten Werner

Journal: Medicine (Baltimore). 2017 Aug;96(34):e7708.

 

Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that if left untreated may lead to the development of cirrhosis. Previous studies on AIH patients have suggested that fibrosis and even cirrhosis can be reversed by medical treatment. The aim of this study was to evaluate ...

Last Updated: 23 Aug 2017

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Population-based prevalence, incidence, and disease burden of autoimmune hepatitis in South Korea.
 

Author(s): Bo Hyun Kim, Hwa Young Choi, Moran Ki, Kyung-Ah Kim, Eun Sun Jang, Sook-Hyang Jeong

Journal:

 

Little is known about population-based epidemiology and disease burden of autoimmune hepatitis (AIH). The aim of this study was to investigate the prevalence, incidence, comorbidity and direct medical cost of AIH in South Korea.

Last Updated: 3 Aug 2017

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Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy.
 

Author(s): Jana Diestelhorst, Norman Junge, Jerome Schlue, Christine S Falk, Michael P Manns, Ulrich Baumann, Elmar Jaeckel, Richard Taubert

Journal:

 

The autoimmune hepatitis (AIH) is a chronic hepatitis driven by the adaptive immunity that affects all age groups. A functional and numerical regulatory T cell (Treg) defect has been reported in pediatric AIH (pAIH), while an intrahepatic increase in adult AIH (aAIH) patients has ...

Last Updated: 12 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 83 free, full-text review articles on human participants. First 3 results:

The use of immunosuppression in autoimmune hepatitis: A current literature review.
 

Author(s): Angela Cropley, Martin Weltman

Journal: Clin Mol Hepatol. 2017 Mar;23(1):22-26.

 

Autoimmune hepatitis (AIH) is an organ specific autoimmune condition which can manifest at any age of life. The heterogeneous nature of this condition means that great variation can be seen in severity, progression of disease and response to treatment within this patient group. Since ...

Last Updated: 14 Mar 2017

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Histopathological aspects in autoimmune cutaneous manifestations associated with hepatitis C virus infection.
 

Author(s): Laura Stătescu, Dan VâŢă, Delia Ciobanu, Laura Gheucă Solovăstru, Maria Rotaru

Journal: Rom J Morphol Embryol. 2016 ;57(3):937-941.

 

Autoimmunity is characterized by activation of the immune system that attacks and destroys wrongly, the body's own structures. All body tissues can be affected (erythrocytes, leukocytes, platelets, blood vessels, muscle tissue, endocrine system, and other), including the skin. Autoimmune ...

Last Updated: 21 Dec 2016

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Immunopathogenic Mechanisms of Autoimmune Hepatitis: How Much Do We Know from Animal Models?
 

Author(s): Urs Christen, Edith Hintermann

Journal:

 

Autoimmune hepatitis (AIH) is characterized by a progressive destruction of the liver parenchyma and a chronic fibrosis. The current treatment of autoimmune hepatitis is still largely dependent on the administration of corticosteroids and cytostatic drugs. For a long time the development ...

Last Updated: 5 Dec 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 19 Dec 2016

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 11 Jul 2016

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Mindfulness - Based Stress Reduction and the Relationship on Inflammation in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 25 Apr 2017

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