Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 442 free, full-text research articles on human participants. First 3 results:

Protocol of a prospective study for the combination treatment of Shu-Gan-jian-Pi decoction and steroid standard therapy in autoimmune hepatitis patients.
 

Author(s): Xiao-Ling Chi, Huan-Ming Xiao, Yu-Bao Xie, Gao-Shu Cai, Jun-Min Jiang, Guang-Jun Tian, Mei-Jie Shi, Shu-Duo Wu, Peng-Tao Zhao, Hui-Jun Chen

Journal:

 

Prednisone plus azathioprine is considered the mainstay of therapy in the current recommendations for autoimmune hepatitis (AIH). However, it does not provide good benefits for AIH patients because of its serious side effects. Therefore, more and more AIH patients prefer to seek for ...

Last Updated: 7 Dec 2016

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Familial occurrence of autoimmune liver disease with overlapping features of primary biliary cholangitis and autoimmune hepatitis in a mother and her daughter.
 

Author(s): Kaoru Omori, Kanako Yoshida, Masaki Yokota, Tsutomu Daa, Masahiro Kan

Journal: Clin J Gastroenterol. 2016 Oct;9(5):312-8.

 

We encountered two patients with overlapping features of primary biliary cholangitis and autoimmune hepatitis within the same family. A 68-year-old woman presented at our hospital from a previous medical institution because of the diagnosis of primary biliary cholangitis. Her 49-year-old ...

Last Updated: 24 Sep 2016

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SEQUENCE SIMILARITY BETWEEN THYROID SELF-PROTEIN AND HEPATITIS C VIRUS POLYPROTEIN: possible triggering mechanism of autoimmune thyroiditis.
 

Author(s): Maristella de Araújo Carvalho Sousa, Raymundo Paraná, Luís Jesuíno de Oliveira Andrade

Journal: Arq Gastroenterol. ;53(3):185-91.

 

- Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus and human proteins can activate autoimmune disease.

Last Updated: 21 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 76 free, full-text review articles on human participants. First 3 results:

De novo autoimmune hepatitis in liver transplant: State-of-the-art review.
 

Author(s): Ranka Vukotic, Giovanni Vitale, Antonia D'Errico-Grigioni, Luigi Muratori, Pietro Andreone

Journal: World J. Gastroenterol.. 2016 Mar;22(10):2906-14.

 

In the two past decades, a number of communications, case-control studies, and retrospective reports have appeared in the literature with concerns about the development of a complex set of clinical, laboratory and histological characteristics of a liver graft dysfunction that is compatible ...

Last Updated: 14 Mar 2016

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Diagnosis and Management of Autoimmune Hepatitis: Current Status and Future Directions.
 

Author(s): Albert J Czaja

Journal: Gut Liver. 2016 Mar;10(2):177-203.

 

Autoimmune hepatitis is characterized by autoantibodies, hypergammaglobulinemia, and interface hepatitis on histological examination. The features lack diagnostic specificity, and other diseases that may resemble autoimmune hepatitis must be excluded. The clinical presentation may ...

Last Updated: 3 Mar 2016

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Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child. Case report and review of the literature.
 

Author(s): Katarina Sedej, Nataša Toplak, Marina Praprotnik, Boštjan Luzar, Jernej Brecelj, Tadej Avčin

Journal:

 

Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described.

Last Updated: 11 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 19 Dec 2016

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 11 Jul 2016

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Mindfulness - Based Stress Reduction and the Relationship on Inflammation in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 14 Feb 2017

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