Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 491 free, full-text research articles on human participants. First 3 results:

Comparison of Concanavalin a-Induced Murine Autoimmune Hepatitis Models.
 

Author(s): Tinghong Ye, Tingting Wang, Xiaoxue Yang, Xiaoli Fan, Maoyao Wen, Yi Shen, Xiaotan Xi, Ruoting Men, Li Yang

Journal: Cell. Physiol. Biochem.. 2018 ;46(3):1241-1251.

 

Autoimmune hepatitis (AIH) is a chronic necroinflammatory disease of the liver whose pathogenic mechanisms have not yet been elucidated. Moreover, the current treatment used for the vast majority of AIH patients is largely dependent on immunosuppressant administration and liver transplantation. ...

Last Updated: 31 Dec 1969

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Evaluation of classical and novel autoantibodies for the diagnosis of Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome (PBC-AIH OS).
 

Author(s): Henry H Nguyen, Abdel Aziz Shaheen, Natalia Baeza, Ellina Lytvyak, Stefan J Urbanski, Andrew L Mason, Gary L Norman, Marvin J Fritzler, Mark G Swain

Journal:

 

Up to 20% of Primary Biliary Cholangitis (PBC) patients are estimated to have features that overlap with Autoimmune Hepatitis (AIH). Patients with PBC-AIH overlap syndrome (PBC-AIH OS) have been reported to exhibit suboptimal responses to ursodeoxycholic acid therapy, and are more ...

Last Updated: 31 Dec 1969

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Primary cutaneous amyloidosis associated with autoimmune hepatitis-primary biliary cirrhosis overlap syndrome and Sjögren syndrome: A case report.
 

Author(s): Xin Yan, Jinglan Jin

Journal: Medicine (Baltimore). 2018 Feb;97(8):e0004.

 

Primary cutaneous amyloidosis (PCA) is a localized skin disorder characterized by the abnormal deposition of amyloid in the extracellular matrix of the dermis. The association between PCA and other diseases, although rare, has been documented for various autoimmune diseases. PCA associated ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 85 free, full-text review articles on human participants. First 3 results:

Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments.
 

Author(s): Benedetta Terziroli Beretta-Piccoli, Giorgina Mieli-Vergani, Diego Vergani

Journal: World J. Gastroenterol.. 2017 Sep;23(33):6030-6048.

 

Autoimmune hepatitis is a rare chronic inflammatory liver disease, affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis at liver histology and good response to immunosuppressive treatment. If untreated, ...

Last Updated: 31 Dec 1969

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Autoimmune Hepatitis in the Liver Transplant Graft.
 

Author(s): Eliza W Beal, Sylvester M Black, Anthony Michaels

Journal: Clin Liver Dis. 2017 May;21(2):381-401.

 

Recurrent autoimmune hepatitis (AIH) and de novo AIH are 2 important causes of late graft failure after liver transplantation (LT). Recurrent AIH occurs in patients who undergo LT for AIH. De novo AIH occurs in patients who are transplanted for etiologies other than AIH. Although ...

Last Updated: 31 Dec 1969

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The use of immunosuppression in autoimmune hepatitis: A current literature review.
 

Author(s): Angela Cropley, Martin Weltman

Journal: Clin Mol Hepatol. 2017 Mar;23(1):22-26.

 

Autoimmune hepatitis (AIH) is an organ specific autoimmune condition which can manifest at any age of life. The heterogeneous nature of this condition means that great variation can be seen in severity, progression of disease and response to treatment within this patient group. Since ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 8 Jan 2018

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 8 Jan 2018

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Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 18 Apr 2018

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