Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 342 free, full-text research articles on human participants. First 3 results:

Mixed connective tissue disease associated with autoimmune hepatitis and pulmonary fibrosis.
 

Author(s): Eva Zold, Edit Bodolay, Balazs Dezső, Györgyike Soos, Britt Nakken, Peter Szodoray

Journal: Isr. Med. Assoc. J.. 2014 Nov;16(11):733-4.

 

Last Updated: 6 Jan 2015

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Presence of antibodies against self human leukocyte antigen class II molecules in autoimmune hepatitis.
 

Author(s): Satoshi Yamagiwa, Hiroteru Kamimura, Masaaki Takamura, Takuya Genda, Takafumi Ichida, Minoru Nomoto, Yutaka Aoyagi

Journal:

 

Autoimmune hepatitis (AIH) can arise de novo after liver transplantation (LT) for non-autoimmune liver diseases. Considering the identical features of de novo AIH after LT and classical AIH, as well as the importance of anti-human leukocyte antigen (HLA) antibodies in graft rejection, ...

Last Updated: 11 Jul 2014

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Clinical characteristics and corticosteroid therapy in patients with autoimmune-hepatitis-induced liver failure.
 

Author(s): Bing Zhu, Shao-Li You, Zhi-Hong Wan, Hong-Ling Liu, Yi-Hui Rong, Hong Zang, Shao-Jie Xin

Journal: World J. Gastroenterol.. 2014 Jun;20(23):7473-9.

 

To investigate the clinical features, response to corticosteroids, and prognosis of autoimmune hepatitis (AIH)-induced liver failure in China.

Last Updated: 26 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 50 free, full-text review articles on human participants. First 3 results:

Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A.
 

Author(s): Hyo Jeong Chang, Dong Hyun Sinn, Sung Gyun Cho, Tae Hoon Oh, Tae Joo Jeon, Won Chang Shin, Won Choong Choi

Journal: Clin Mol Hepatol. 2014 Jun;20(2):204-7.

 

Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-year-old female with a diagnosis of AHA presented with ...

Last Updated: 17 Jul 2014

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Useful biomarkers for assessment of hepatitis C virus infection-associated autoimmune disorders.
 

Author(s): Deng-Ho Yang, Ling-Jun Ho, Jenn-Haung Lai

Journal: World J. Gastroenterol.. 2014 Mar;20(11):2962-70.

 

During the course of chronic hepatitis C virus (HCV) infection, various extrahepatic manifestations of autoimmune disorders may occur, including arthralgia/arthritis, sicca complex, purpura, cutaneous ulcer, and thyroid dysfunction. In addition, the prevalence of circulating autoantibodies ...

Last Updated: 24 Mar 2014

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Natural killer T (NKT) cells in autoimmune hepatitis.
 

Author(s): Jochen Mattner

Journal: Curr. Opin. Immunol.. 2013 Dec;25(6):697-703.

 

Natural killer T (NKT) cells represent an innate-like lymphocyte population endowed with unique antigen recognition and tissue distribution features. Their abundance in the microvascular compartments of the liver allows NKT cells to immediately respond to lipid antigens and soluble ...

Last Updated: 6 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 20 Jan 2015

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Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 26 Jul 2010

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 20 Jan 2015

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