Autoimmune Hepatitis

Common Name(s)

Autoimmune Hepatitis

Autoimmune hepatitis is a disease in which the body’s immune system attacks liver cells. This immune response causes inflammation of the liver, also called hepatitis. The disease can be quite serious and, if not treated, gets worse over time, leading to cirrhosis of the liver and/or liver failure.  Autoimmune hepatitis sometimes occurs in relatives of people with autoimmune diseases, suggesting a genetic cause. This disease is most common in young girls and women
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Hepatitis" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Hepatitis" returned 449 free, full-text research articles on human participants. First 3 results:

Autoimmune hepatitis in patients with human immunodeficiency virus (HIV): Case reports of a rare, but important diagnosis with therapeutic implications.
 

Author(s): Leila Kia, Adam Beattie, Richard M Green

Journal: Medicine (Baltimore). 2017 Feb;96(7):e6011.

 

Chronic liver disease is a major cause of morbidity and mortality in patients with HIV. However, autoimmune hepatitis (AIH) in patients with HIV has rarely been reported. Our aim was to evaluate a cohort of patients with HIV and AIH and identify clinical presentations and outcomes.

Last Updated: 16 Feb 2017

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Innumerable Liver Masses in a Patient with Autoimmune Hepatitis and Primary Sclerosing Cholangitis Overlap Syndrome.
 

Author(s): Alireza Gharibpoor, Fariborz Mansour-Ghanaei, Mahbobe Sadeghi, Faeze Gharibpoor, Farahnaz Joukar, Sara Mavaddati

Journal:

 

BACKGROUND In patients with the diagnosis of autoimmune hepatitis (AIH), the presence of cholestatic features raise the possibility of an overlap syndrome with primary sclerosing cholangitis (PSC). Here, we present a unique case with AIH-PSC overlap syndrome and innumerable liver ...

Last Updated: 7 Feb 2017

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Autoimmune Hepatitis Associated with Immune Thrombocytopenic Purpura.
 

Author(s): Akihiro Ito, Kaname Yoshizawa, Kazuya Fujimori, Susumu Morita, Takashi Shigeno, Toshitaka Maejima

Journal: Intern. Med.. 2017 ;56(2):143-147.

 

Although autoimmune hepatitis (AIH) is frequently complicated with chronic thyroiditis or other autoimmune disorders, reports on its association with immune thrombocytopenic purpura (ITP) are scarce. We herein describe a case of AIH associated with ITP. A 75-year-old Japanese woman ...

Last Updated: 16 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Hepatitis" returned 78 free, full-text review articles on human participants. First 3 results:

Immunopathogenic Mechanisms of Autoimmune Hepatitis: How Much Do We Know from Animal Models?
 

Author(s): Urs Christen, Edith Hintermann

Journal:

 

Autoimmune hepatitis (AIH) is characterized by a progressive destruction of the liver parenchyma and a chronic fibrosis. The current treatment of autoimmune hepatitis is still largely dependent on the administration of corticosteroids and cytostatic drugs. For a long time the development ...

Last Updated: 5 Dec 2016

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Autoimmune Hepatitis: Progress from Global Immunosuppression to Personalised Regulatory T Cell Therapy.
 

Author(s): Nwe Ni Than, Hannah C Jeffery, Ye H Oo

Journal: Can J Gastroenterol Hepatol. 2016 ;2016():7181685.

 

Autoimmune hepatitis (AIH) is an immune mediated liver injury. The precise aetiology of AIH is still unknown but current evidence suggests both genetic and environmental factors are involved. Breakdown in peripheral self-tolerance, and impaired functions of FOXP3(+) regulatory T cell ...

Last Updated: 22 Jul 2016

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De novo autoimmune hepatitis in liver transplant: State-of-the-art review.
 

Author(s): Ranka Vukotic, Giovanni Vitale, Antonia D'Errico-Grigioni, Luigi Muratori, Pietro Andreone

Journal: World J. Gastroenterol.. 2016 Mar;22(10):2906-14.

 

In the two past decades, a number of communications, case-control studies, and retrospective reports have appeared in the literature with concerns about the development of a complex set of clinical, laboratory and histological characteristics of a liver graft dysfunction that is compatible ...

Last Updated: 14 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Sodium Chloride and the Treg/Th17 Axis in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 19 Dec 2016

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De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation
 

Status: Recruiting

Condition Summary: De Novo Autoimmune Hepatitis

 

Last Updated: 11 Jul 2016

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Mindfulness - Based Stress Reduction and the Relationship on Inflammation in Autoimmune Hepatitis
 

Status: Recruiting

Condition Summary: Autoimmune Hepatitis

 

Last Updated: 14 Feb 2017

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