Autoimmune Diseases

Common Name(s)

Autoimmune Diseases

An autoimmune disease is a disorder in which the body mistakenly attacks healthy tissues. There are over 80 different types of autoimmune diseases. Autoimmune diseases may result in fatigue, fever, destruction of one or more body tissues, abnormal growth of an organ, and changes in organ function. Several tests can be used to diagnose autoimmune diseases, including: antinuclear antibody tests, autoantibody tests, CBC, and C-reactive protein tests. Treatment typically involves medicine to control or reduce the immune systems response (meaning that the body will stop attacking itself). Other treatment varies based on the type of disease, for example, if the autoimmune disease affects your blood, you may need a blood transfusion, or you may need hormone supplements if your body is lacking hormones as a result of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Diseases" for support, advocacy or research.

American Autoimmune Related Diseases Association, Inc.

American Autoimmune Related Diseases Association is the nation's only organization dedicated to bringing a national focus to autoimmunity as a category of disease and a major women's health issue and to promoting a collaborative research effort in order to find better treatments and a cure for all autoimmune diseases.

Last Updated: 26 Nov 2014

View Details
APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

View Details
Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

View Details
National Foundation for Celiac Awareness

The National Foundation for Celiac Awareness advances widespread understanding of celiac disease as a serious genetic autoimmune condition and works to secure early diagnosis and effective management. We empower our community to live life to the fullest, and serve as a leading and trusted resource that inspires hope, accelerates innovation and forges pathways to a cure.

Last Updated: 19 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autoimmune Diseases" for support, advocacy or research.

American Autoimmune Related Diseases Association, Inc.

American Autoimmune Related Diseases Association is the nation's only organization dedicated to bringing a national focus to autoimmunity as a category of disease and a major women's health issue and to promoting a collaborative research effort in order to find better treatments and a cure for all autoimmune diseases.

http://www.aarda.org

Last Updated: 26 Nov 2014

View Details
APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

View Details
National Foundation for Celiac Awareness

The National Foundation for Celiac Awareness advances widespread understanding of celiac disease as a serious genetic autoimmune condition and works to secure early diagnosis and effective management. We empower our community to live life to the fullest, and serve as a leading and trusted resource that inspires hope, accelerates innovation and forges pathways to a cure.

http://www.CeliacCentral.org

Last Updated: 19 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

Go To URL
 
 
Top

Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autoimmune Diseases" returned 445 free, full-text research articles on human participants. First 3 results:

Taenia solium in a patient with systemic lupus erythematosus: do parasites protect against autoimmune diseases.
 

Author(s): Lior Zeller, Leonid Barski, Elena Shleyfer, Uri Netz, Vered Stavi, Mahmoud Abu-Shakra

Journal: Isr. Med. Assoc. J.. 2015 Apr;17(4):259-60.

 

Last Updated: 4 Jun 2015

Go To URL
RNASET2 tag SNP but not CCR6 polymorphisms is associated with autoimmune thyroid diseases in the Chinese Han population.
 

Author(s): Xiao-jun Chen, Xiao-hua Gong, Ni Yan, Shuai Meng, Qiu Qin, Yan-Fei Jiang, Hai-Yan Zheng, Jin-an Zhang

Journal:

 

Polymorphisms of the CC chemokine receptor 6 (CCR6) and RNASET2 tag SNP have been shown to be associated with the susceptibility to several immune-related diseases. This study was conducted to identify the association of CCR6 and RNASET2 tag SNP with autoimmune thyroid diseases (AITDs) ...

Last Updated: 1 May 2015

Go To URL
UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
 

Author(s): Myles J Lewis, Simon Vyse, Adrian M Shields, Sebastian Boeltz, Patrick A Gordon, Timothy D Spector, Paul J Lehner, Henning Walczak, Timothy J Vyse

Journal: Am. J. Hum. Genet.. 2015 Feb;96(2):221-34.

 

UBE2L3 is associated with increased susceptibility to numerous autoimmune diseases, but the underlying mechanism is unexplained. By using data from a genome-wide association study of systemic lupus erythematosus (SLE), we observed a single risk haplotype spanning UBE2L3, consistently ...

Last Updated: 9 Feb 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autoimmune Diseases" returned 305 free, full-text review articles on human participants. First 3 results:

Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.
 

Author(s): André Ballesteros-Tato

Journal: Immunotherapy. 2014 ;6(11):1207-20.

 

Low-dose IL-2 administration suppresses unwanted immune responses in mice and humans, thus evidencing the potential of IL-2 to treat autoimmune disorders. Increased Tregs activity is one of the potential mechanisms by which low-dose IL-2 immunotherapy induces immunosuppression. In ...

Last Updated: 16 Dec 2014

Go To URL
Direct and indirect pathogenic roles of autoantibodies in systemic autoimmune diseases.
 

Author(s): Takao Fujii

Journal: Allergol Int. 2014 Dec;63(4):515-22.

 

Autoantibody (autoAb) production in patients with systemic autoimmune diseases is a hallmark of disease entity, activity and prognosis. Although a large number of autoAbs have been discovered to date, there is a limited number of autoAbs whose pathogenic roles have been clearly determined. ...

Last Updated: 26 Nov 2014

Go To URL
Role of Helicobacter pylori infection in autoimmune systemic rheumatic diseases.
 

Author(s): Mislav Radić

Journal: World J. Gastroenterol.. 2014 Sep;20(36):12839-46.

 

The relationship between infection and autoimmunity has been increasingly defined over the last 20 years. The systemic rheumatic diseases are characterized by dysregulation of the immune system resulting in a loss of tolerance to self-antigen. The exact etiology for the majority of ...

Last Updated: 3 Oct 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Transcriptome Analysis of the Peripheral Blood in CIDP
 

Status: Recruiting

Condition Summary: Chronic Inflammatory Demyelinating Polyradiculoneuropathy; Autoimmune Diseases; Clarkson Syndrome; Muscular Autoimmune Disorders

 

Last Updated: 30 Mar 2015

Go to URL
Sudoscan in Patients With Autoimmune Disorders
 

Status: Recruiting

Condition Summary: Autoimmune Disease

 

Last Updated: 27 Jul 2015

Go to URL
Autologous SCT for Progressive Systemic Sclerosis: a Prospective NIS Study
 

Status: Recruiting

Condition Summary: Autoimmune Diseases

 

Last Updated: 17 Oct 2014

Go to URL