Spasticity

Common Name(s)

Spasticity

Spasticity is a muscular condition characterized by involuntary movements and stiffness. Affected individuals will experience resistance when attempting movements due to muscles being involuntarily contracted. This condition may make small movements, such as buttoning a shirt, very difficult. Spasticity is caused by injury to the brain, spinal cord, or nerves as a result of trauma, stroke, or neuromuscular disorders. This injury results in abnormal signaling between the brain and muscles, causing the abnormal contraction of muscles. Many stroke survivors and over 80% of individuals with multiple sclerosis are affected by spasticity.

Common signs of spasticity include abnormal posture, a clenched fist, and flexed elbows, hands, or fingers. Individuals affected by spasticity may experience symptoms ranging from minor stiffness and inflexibility to involuntary and painful spasms. Other symptoms include difficulty speaking, jerky motions, pain with movement, and very strong reflexes. When an individual has severe spasticity for a long time, their muscle may decrease in size. This may lead to reduced range of motion or the inability to move a joint from a fixed position.

Diagnosis and treatment of spasticity are important to minimize symptoms in affected individuals. Proper treatment can reduce limitations, prevent further injury, and improve quality of life. Treatment for spasticity depends on the severity of the symptoms and overall health of the affected individual. Braces are often used to keep a muscle in a desired position. Physical therapy and exercises often help to strengthen muscles, maintain full range of motion, and reduce risk of permanent muscle damage. Medications taken as pills, injections, and/or implanted devices may be used to help relax muscles. If you or your child has been diagnosed with spasticity, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spasticity" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spasticity" returned 385 free, full-text research articles on human participants. First 3 results:

Is two better than one? Muscle vibration plus robotic rehabilitation to improve upper limb spasticity and function: A pilot randomized controlled trial.
 

Author(s): Rocco Salvatore Calabrò, Antonino Naro, Margherita Russo, Demetrio Milardi, Antonino Leo, Serena Filoni, Antonia Trinchera, Placido Bramanti

Journal:

 

Even though robotic rehabilitation is very useful to improve motor function, there is no conclusive evidence on its role in reducing post-stroke spasticity. Focal muscle vibration (MV) is instead very useful to reduce segmental spasticity, with a consequent positive effect on motor ...

Last Updated: 3 Oct 2017

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Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study).
 

Author(s): Silvia Messina, Claudio Solaro, Isabella Righini, Roberto Bergamaschi, Simona Bonavita, Roberto Bruno Bossio, Vincenzo Brescia Morra, Gianfranco Costantino, Paola Cavalla, Diego Centonze, Giancarlo Comi, Salvatore Cottone, Maura Chiara Danni, Ada Francia, Alberto Gajofatto, Claudio Gasperini, Mauro Zaffaroni, Loredana Petrucci, Elisabetta Signoriello, Giorgia Teresa Maniscalco, Gabriella Spinicci, Manuela Matta, Massimiliano Mirabella, Graziella Pedà, Letizia Castelli, Marco Rovaris, Edoardo Sessa, Daniele Spitaleri, Damiano Paolicelli, Alfredo Granata, Mario Zappia, Francesco Patti,

Journal:

 

The approval of Sativex for the management of multiple sclerosis (MS) spasticity opened a new opportunity to many patients. In Italy, the healthcare payer can be fully reimbursed by the involved pharma company with the cost of treatment for patients not responding after a 4 week (28 ...

Last Updated: 1 Aug 2017

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Gait asymmetry, ankle spasticity, and depression as independent predictors of falls in ambulatory stroke patients.
 

Author(s): Ta-Sen Wei, Peng-Ta Liu, Liang-Wey Chang, Sen-Yung Liu

Journal:

 

Falls are the leading cause of injury in stroke patients. However, the cause of a fall is complicated, and several types of risk factors are involved. Therefore, a comprehensive model to predict falls with high sensitivity and specificity is needed.

Last Updated: 25 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spasticity" returned 51 free, full-text review articles on human participants. First 3 results:

Efficacy and safety of oral baclofen in the management of spasticity: A rationale for intrathecal baclofen.
 

Author(s): Per Ertzgaard, Claudia Campo, Alessandra Calabrese

Journal: J Rehabil Med. 2017 Mar;49(3):193-203.

 

Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a rationale for the use of intrathecal ...

Last Updated: 24 Feb 2017

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Assessing and treating pain associated with stroke, multiple sclerosis, cerebral palsy, spinal cord injury and spasticity. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
 

Author(s): Stefano Paolucci, Andrea Martinuzzi, Giorgio Scivoletto, Nicola Smania, Claudio Solaro, Irene Aprile, Michela Armando, Roberto Bergamaschi, Eliana Berra, Giulia Berto, Elena Carraro, Monica Cella, Marialuisa Gandolfi, Marcella Masciullo, Marco Molinari, Emanuela Pagliano, Cristiano Pecchioli, Laura Roncari, Monica Torre, Erika Trabucco, Gabriella Vallies, Paolo Zerbinati, Stefano Tamburin,

Journal: Eur J Phys Rehabil Med. 2016 Dec;52(6):827-840.

 

Pain is a common and disabling symptom in patients with stroke, multiple sclerosis (MS), cerebral palsy (CP), spinal cord injury (SCI) and other conditions associated with spasticity, but data on its prevalence, and natural history, as well as guidelines on its assessment and treatment ...

Last Updated: 6 Sep 2016

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Baclofen in the Therapeutic of Sequele of Traumatic Brain Injury: Spasticity.
 

Author(s): Adán Pérez-Arredondo, Eduardo Cázares-Ramírez, Paul Carrillo-Mora, Marina Martínez-Vargas, Noemí Cárdenas-Rodríguez, Elvia Coballase-Urrutia, Radamés Alemón-Medina, Aristides Sampieri, Luz Navarro, Liliana Carmona-Aparicio

Journal: Clin Neuropharmacol. ;39(6):311-319.

 

Traumatic brain injury (TBI) is an alteration in brain function, caused by an external force, which may be a hit on the skull, rapid acceleration or deceleration, penetration of an object, or shock waves from an explosion. Traumatic brain injury is a major cause of morbidity and mortality ...

Last Updated: 26 Aug 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Peripheral Modulation of Muscle Stiffness and Spasticity
 

Status: Not yet recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 9 Oct 2017

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Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity
 

Status: Not yet recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 29 Apr 2016

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Last Updated: 5 Oct 2017

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