Spasticity

Common Name(s)

Spasticity

Spasticity is a muscular condition characterized by involuntary movements and stiffness. Affected individuals will experience resistance when attempting movements due to muscles being involuntarily contracted. This condition may make small movements, such as buttoning a shirt, very difficult. Spasticity is caused by injury to the brain, spinal cord, or nerves as a result of trauma, stroke, or neuromuscular disorders. This injury results in abnormal signaling between the brain and muscles, causing the abnormal contraction of muscles. Many stroke survivors and over 80% of individuals with multiple sclerosis are affected by spasticity.

Common signs of spasticity include abnormal posture, a clenched fist, and flexed elbows, hands, or fingers. Individuals affected by spasticity may experience symptoms ranging from minor stiffness and inflexibility to involuntary and painful spasms. Other symptoms include difficulty speaking, jerky motions, pain with movement, and very strong reflexes. When an individual has severe spasticity for a long time, their muscle may decrease in size. This may lead to reduced range of motion or the inability to move a joint from a fixed position.

Diagnosis and treatment of spasticity are important to minimize symptoms in affected individuals. Proper treatment can reduce limitations, prevent further injury, and improve quality of life. Treatment for spasticity depends on the severity of the symptoms and overall health of the affected individual. Braces are often used to keep a muscle in a desired position. Physical therapy and exercises often help to strengthen muscles, maintain full range of motion, and reduce risk of permanent muscle damage. Medications taken as pills, injections, and/or implanted devices may be used to help relax muscles. If you or your child has been diagnosed with spasticity, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spasticity" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spasticity" returned 341 free, full-text research articles on human participants. First 3 results:

Early prediction of long-term upper limb spasticity after stroke: part of the SALGOT study.
 

Author(s): Arve Opheim, Anna Danielsson, Margit Alt Murphy, Hanna C Persson, Katharina Stibrant Sunnerhagen

Journal: Neurology. 2015 Sep;85(10):873-80.

 

To identify predictors and the optimal time point for the early prediction of the presence and severity of spasticity in the upper limb 12 months poststroke.

Last Updated: 8 Sep 2015

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Factors influencing goal attainment in patients with post-stroke upper limb spasticity following treatment with botulinum toxin A in real-life clinical practice: sub-analyses from the Upper Limb International Spasticity (ULIS)-II Study.
 

Author(s): Klemens Fheodoroff, Stephen Ashford, Jorge Jacinto, Pascal Maisonobe, Jovita Balcaitiene, Lynne Turner-Stokes

Journal:

 

In this post-hoc analysis of the ULIS-II study, we investigated factors influencing person-centred goal setting and achievement following botulinum toxin-A (BoNT-A) treatment in 456 adults with post-stroke upper limb spasticity (ULS). Patients with primary goals categorised as passive ...

Last Updated: 10 Apr 2015

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Color Doppler ultrasound-guided botulinum toxin type A injection combined with an ankle foot brace for treating lower limb spasticity after a stroke.
 

Author(s): X-D Ding, G-B Zhang, H-X Chen, W Wang, J-H Song, D-G Fu

Journal: Eur Rev Med Pharmacol Sci. 2015 ;19(3):406-11.

 

To explore the effectiveness of the color Doppler ultrasound-guided botulinum toxin type A (BTX-A) injection combined with an ankle foot brace (AFO) for treating lower limb spasticity after a stroke.

Last Updated: 27 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spasticity" returned 46 free, full-text review articles on human participants. First 3 results:

Spasticity and its contribution to hypertonia in cerebral palsy.
 

Author(s): Lynn Bar-On, Guy Molenaers, Erwin Aertbeliën, Anja Van Campenhout, Hilde Feys, Bart Nuttin, Kaat Desloovere

Journal: Biomed Res Int. 2015 ;2015():317047.

 

Spasticity is considered an important neural contributor to muscle hypertonia in children with cerebral palsy (CP). It is most often treated with antispasticity medication, such as Botulinum Toxin-A. However, treatment response is highly variable. Part of this variability may be due ...

Last Updated: 4 Feb 2015

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Pathophysiology of spasticity: implications for neurorehabilitation.
 

Author(s): Carlo Trompetto, Lucio Marinelli, Laura Mori, Elisa Pelosin, Antonio Currà, Luigi Molfetta, Giovanni Abbruzzese

Journal: Biomed Res Int. 2014 ;2014():354906.

 

Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex. It is only one of the several components of the upper motor neuron syndrome (UMNS). The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory ...

Last Updated: 22 Dec 2014

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Data condensed synthesis regarding kinesiotherapeutic procedures used in spasticity therapy.
 

Author(s): E Moraru, G Onose

Journal: J Med Life. 2014 Sep;7(3):317-21.

 

Spasticity represents an important feature of the upper motoneuron syndrome (UMNS). The clinical signs, such as the abnormal movement models, the unwanted muscular co-contractions, the muscular and joint rigidity with a consecutive deformity can be signs of spasticity and, also of ...

Last Updated: 21 Nov 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Energy Costs of Spasticity in Spinal Cord Injury: A Pilot Investigation
 

Status: Recruiting

Condition Summary: Basal Energy Expenditure; Spasticity

 

Last Updated: 1 Jul 2010

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Developing and Testing a Comprehensive MS Spasticity Management Program
 

Status: Not yet recruiting

Condition Summary: Multiple Sclerosis; Spasticity

 

Last Updated: 15 May 2015

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