Spasticity

Common Name(s)

Spasticity

Spasticity is a muscular condition characterized by involuntary movements and stiffness. Affected individuals will experience resistance when attempting movements due to muscles being involuntarily contracted. This condition may make small movements, such as buttoning a shirt, very difficult. Spasticity is caused by injury to the brain, spinal cord, or nerves as a result of trauma, stroke, or neuromuscular disorders. This injury results in abnormal signaling between the brain and muscles, causing the abnormal contraction of muscles. Many stroke survivors and over 80% of individuals with multiple sclerosis are affected by spasticity.

Common signs of spasticity include abnormal posture, a clenched fist, and flexed elbows, hands, or fingers. Individuals affected by spasticity may experience symptoms ranging from minor stiffness and inflexibility to involuntary and painful spasms. Other symptoms include difficulty speaking, jerky motions, pain with movement, and very strong reflexes. When an individual has severe spasticity for a long time, their muscle may decrease in size. This may lead to reduced range of motion or the inability to move a joint from a fixed position.

Diagnosis and treatment of spasticity are important to minimize symptoms in affected individuals. Proper treatment can reduce limitations, prevent further injury, and improve quality of life. Treatment for spasticity depends on the severity of the symptoms and overall health of the affected individual. Braces are often used to keep a muscle in a desired position. Physical therapy and exercises often help to strengthen muscles, maintain full range of motion, and reduce risk of permanent muscle damage. Medications taken as pills, injections, and/or implanted devices may be used to help relax muscles. If you or your child has been diagnosed with spasticity, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spasticity" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spasticity" returned 411 free, full-text research articles on human participants. First 3 results:

Combined treatment of botulinumtoxin and robot-assisted rehabilitation therapy on poststroke, upper limb spasticity: A case report.
 

Author(s): So Young Lee, Young Tae Jeon, Bo Ryun Kim, Eun Young Han

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9468.

 

Spasticity is a major complication after stroke, and botulinumtoxin A (BoNT-A) injection is commonly used to manage focal spasticity. However, it is uncertain whether BoNT-A can improve voluntary motor control or activities of daily living function of paretic upper limbs. This study ...

Last Updated: 31 Dec 1969

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Initial psychometric validation of the questionnaire on pain caused by spasticity (QPS).
 

Author(s): Thorin L Geister, Donald M Bushnell, Jie Yang, Yuqiong Zhang, Mona L Martin, Alev Heilbronn, Zhenhuan Liu

Journal:

 

The Questionnaire on Pain caused by Spasticity (QPS) is a modular patient- and observer-reported outcome measure of spasticity-related pain (SRP) in children with cerebral palsy (CP). Originally developed for an English-speaking population, we conducted a psychometric validation of ...

Last Updated: 31 Dec 1969

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Efficacy of Cerebrolysin in the reduction of spasticity during stroke rehabilitation.
 

Author(s): R M Martinez

Journal: J Med Life. ;10(3):161-166.

 

This study assessed the efficacy of Cerebrolysin on post-stroke spasticity, motor recovery, and global functions in an outpatient rehabilitation setting.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spasticity" returned 54 free, full-text review articles on human participants. First 3 results:

Efficacy and safety of oral baclofen in the management of spasticity: A rationale for intrathecal baclofen.
 

Author(s): Per Ertzgaard, Claudia Campo, Alessandra Calabrese

Journal: J Rehabil Med. 2017 Mar;49(3):193-203.

 

Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a rationale for the use of intrathecal ...

Last Updated: 31 Dec 1969

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Efficacy and safety of botulinum toxin type A for upper limb spasticity after stroke or traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis.
 

Author(s): Yan Dong, Tao Wu, Xiaohua Hu, Tong Wang

Journal: Eur J Phys Rehabil Med. 2017 Apr;53(2):256-267.

 

Muscle spasticity is a positive symptom after stroke and traumatic brain injury. Botulinum toxin type A (BoNT-A) injection is widely used for treating post stroke and traumatic brain injury spasticity. This study aimed to evaluate efficacy and safety of BoNT-A for upper limb spasticity ...

Last Updated: 31 Dec 1969

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[Early pharmacologic treatment with botulinum toxin A in post-stroke spasticity: consensus evidence-based recommendations].
 

Author(s): L Lopez de Munain, F J Juan-Garcia, E Duarte, R Martin-Mourelle, S Rodriguez, S Moraleda-Perez

Journal: Rev Neurol. 2016 Oct;63(8):363-369.

 

Spasticity is a common complication that occurs in those patients that have suffered a stroke. To identify those patients at high risk of having post-stroke spasticity and to start treatment at early stages would probably benefit the patient. The key aspects in the early management ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Peripheral Modulation of Muscle Stiffness and Spasticity
 

Status: Not yet recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 26 Jan 2018

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Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment
 

Status: Recruiting

Condition Summary: Muscle Spasticity

 

Last Updated: 13 Dec 2016

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