Spastic paraparesis

Common Name(s)

Spastic paraparesis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Spastic paraparesis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Spastic paraparesis" returned 144 free, full-text research articles on human participants. First 3 results:

Proprioceptive neuromuscular facilitation in HTLV-I-associated myelopathy/tropical spastic paraparesis.
 

Author(s): Vera LĂșcia Santos de Britto, Rosalie Correa, Maurice Borges Vincent

Journal: Rev. Soc. Bras. Med. Trop.. ;47(1):24-9.

 

Human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) can impact the independence and motricity of patients. The aims of this study were to estimate the effects of physiotherapy on the functionality of patients with HAM/TSP during the ...

Last Updated: 7 Mar 2014

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CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis.
 

Author(s): Tomoo Sato, Ariella Coler-Reilly, Atae Utsunomiya, Natsumi Araya, Naoko Yagishita, Hitoshi Ando, Junji Yamauchi, Eisuke Inoue, Takahiko Ueno, Yasuhiro Hasegawa, Kusuki Nishioka, Toshihiro Nakajima, Steven Jacobson, Shuji Izumo, Yoshihisa Yamano

Journal:

 

Human T-lymphotropic virus type 1 (HTLV-1) -associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. Since the disease course of HAM/TSP varies among patients, there is a dire need for biomarkers capable of predicting the rate of disease ...

Last Updated: 16 Oct 2013

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Therapeutic benefits of an oral vitamin B1 derivative for human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
 

Author(s): Jun-Ichi Kira

Journal:

 

Prosultiamine, a vitamin B1 derivative, has long been used for beriberi neuropathy and Wernicke's encephalopathy. Based on the finding that prosultiamine induces apoptosis in human T lymphotropic virus type I (HTLV-I)-infected T cells, Nakamura et al. conducted a clinical trial of ...

Last Updated: 17 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Spastic paraparesis" returned 9 free, full-text review articles on human participants. First 3 results:

Treatment of HTLV-I-associated myelopathy/tropical spastic paraparesis: toward rational targeted therapy.
 

Author(s): Unsong Oh, Steven Jacobson

Journal: Neurol Clin. 2008 Aug;26(3):781-97, ix-x.

 

The treatment of HAM/TSP is a challenge. No agent has shown to significantly modify the long-term disability associated with HAM/TSP. Advances in our understanding of the pathogenesis of HAM/TSP have led to the identification of several biomarkers and therapeutic targets. Clinical ...

Last Updated: 28 Jul 2008

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Adrenomyeloneuropathy as a cause of primary adrenal insufficiency and spastic paraparesis.
 

Author(s): Monika Spurek, Regina Taylor-Gjevre, Stan Van Uum, Hasnain M Khandwala

Journal: CMAJ. 2004 Oct;171(9):1073-7.

 

Adrenomyeloneuropathy is a varient of adrenoleukodystrophy, both of which are rare inherited disorders of peroxisomes characterized by the accumulation of very-long-chain fatty acids in plasma, the central and peripheral nervous systems, adrenal glands and testes, which leads to dysfunction ...

Last Updated: 26 Oct 2004

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Possible etiologies for tropical spastic paraparesis and human T lymphotropic virus I-associated myelopathy.
 

Author(s): V Zaninovic'

Journal: Braz. J. Med. Biol. Res.. 2004 Jan;37(1):1-12.

 

The epidemiology of tropical spastic paraparesis/human T lymphotropic virus I (HTLV-I)-associated myelopathy (TSP/HAM) is frequently inconsistent and suggests environmental factors in the etiology of these syndromes. The neuropathology corresponds to a toxometabolic or autoimmune ...

Last Updated: 22 Dec 2003

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Patients With HAM/TSP
 

Status: Recruiting

Condition Summary: HTLV-I Infection; Tropical Spastic Paraparesis

 

Last Updated: 14 Mar 2014

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Raltegravir for HAM/TSP
 

Status: Recruiting

Condition Summary: HAM/TSP; HTLV-1

 

Last Updated: 19 Mar 2014

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